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81
Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
Published 2021“…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …”
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The mechanisms of resistance of anthrax lethal toxin (LeTx)-induced cytotoxicity in AML cells. (c2018)
Published 2018“…Our results indicate that vertical inhibition by SCH772984 rendered the resistant cell lines sensitive to the inhibition of the MAPK-pathway and showed an increased cytotoxic effect once used in combination with anthrax lethal toxin compared to the use of anthrax lethal toxin alone.…”
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masterThesis -
84
The July war and its effects on Lebanon’s power-sharing
Published 2007“…On a broader scale, this article helps shed light on the dilemma of power-sharing systems on stormy seas when external conflicts overlap with internal conflict lines.…”
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85
Effectiveness of communication processes in Agile Project Management Approach in the UAE Utility Sector
Published 2023“…Team members should have a voice in the agile project management process, maintain open lines of communication with stakeholders, and discuss problems in a timely manner to increase tolerance and acceptance.…”
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87
Effect of Construction Void Defects on Flexural and Axial Load Capacity of Reinforced Concrete Members
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doctoralThesis -
88
Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes
Published 2011“…The percent reduction in proliferation was very significant, and was dose-, and time-dependent. In both cell lines, kefir exhibited its antiproliferative effect by downregulating TGF-α and upregulating TGF-β1 mRNA expression. …”
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89
Anticancer and antioxidant effects of tragopogon porrifolius extract. (c2011)
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masterThesis -
90
The Effect of Indoor Air Quality on Occupants’ Health and Performance in Office Buildings in Dubai
Published 2013“…As people spend most of their time indoors, enough attention should be given to the indoor environment conditions including the air quality. …”
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91
The Russia-Ukraine war, soaring food prices, and the Turkish economy: insights from computable general equilibrium
Published 2023“…Türkiye, as a neighboring country and a major player in the region, maintains close ties with Ukraine and Russia and heavily relies on agricultural imports from both countries making it susceptible to market shocks caused by the war. …”
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92
The Anti-Tumor Effect of Flaxseed Lignan Derivatives on Different Acute Myeloid Leukemia Cancer Cells
Published 2020“…Moreover, Cell Death ELISA analysis showed a dose-dependent increase in apoptosis, as revealed by an increase in DNA fragmentation. …”
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masterThesis -
93
The Impact of Sporting Events on Air Pollution: An Empirical Examination of National Football League Games
Published 2023“…From this, multiple regression analysis was utilized to estimate whether the number of fans was related to changes in air pollution. (3) Results: The regression models found that Ozone and Nitrogen Dioxide levels increased as more individuals attended NFL games. Additional robustness checks and falsification tests suggest that the average NFL event results in an approximately two-percent increase in Ozone levels. (4) Conclusions: The findings from this study contribute to the literature by providing evidence that highly attended sporting events increase pollution levels in the areas near stadiums. …”
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94
Parallel multi-voltage power minimization in VLSI circuits. (c2013)
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masterThesis -
95
Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015)
Published 2016“…Furthermore, we have attempted to examine the photochemical potential of our metal-organic compound model by combining L-II and L-III in the same metal complex, thus generating four final complexes with differing net charges (from +2 to -4), and examining their activities on a panel of AML cell lines with or without exposure to blue light. Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …”
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masterThesis -
96
Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells
Published 2015“…In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. …”
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97
Impacts of On-Grid Solar PV on Distribution Networks and Potential Solutions: A Case Study in the Region of Zahle
Published 2025“…Recent years have witnessed an increase in the installation of solar photovoltaic-based distributed generators or PV DGs mainly in countries with high solar potential such as Lebanon. …”
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masterThesis -
98
Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
Published 2016“…The pro-apoptotic effect upon combination of topotecan with andrographolide was further observed using annexin V/PI staining; even though andrographolide alone did not alter cell survival, however, when applied to the cells prior to topotecan treatment, the number of apoptotic cells increased from 16% to 57%. Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…”
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99
On Single Source Reachability Improvement
Published 2022“…The problem of augmenting a given network, or graph, via edge-additions for improved reachability from a given source node is considered. …”
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masterThesis -
100
Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells
Published 2013“…In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. …”
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