PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer by Reem Saleh (3513056)

“…In this study, we investigated the molecular mechanisms by which the human TNBC cell line MDA-MB-231, expressing PD-L1, responds to atezolizumab, using RNA-Seq. …”

Prevalence and global trends of polypharmacy in patients with chronic kidney disease: A systematic review and meta-analysis by Lina Naseralallah (14146465)

“…In line with the therapeutic guidelines, managing CKD and its complications necessitates prescribing multiple medications, which predisposes patients to polypharmacy. …”

Need for Affect, Problematic Social Media Use and the Mediating Role of Fear of Missing Out in European and Arab Samples by Areej Babiker (17032314)

“…<h3>Purpose </h3><p dir="ltr">The growing awareness and concern about the excessive use of social media have led to an increasing number of studies investigating the underlying factors contributing to this behavior. …”

The impact of cultural diversity on project management communication by HUSSEIN, ALAA BASSAM FUAD

“…The results of the study are in line with some previous research, who said that when examined in terms of age, gender, and ethnicity, having a diverse workforce has a positive impact on the organization's performance. …”
Get full text

Colon cancer classification using microarray data by Tariq Khan, Saima

“…In treating cancer time is of the essence and early detection can dramatically increase the chances of survival. Imaging techniques, which are the prevalent method of detection and diagnosis, are only useful once the cancerous growth has become visible.However, if techniques that detect cancerous processes at a genetic level are utilized then the cancerous tissues could be identified, and the disease diagnosed much earlier, thus giving a far better prognosis.Therefore, the aim of this thesis is to evaluate the performance of a variety of different classification methods with a particular dataset containing genetic samples of both normal and cancerous biopsies of the colon tissue.A classifier will be recommended which is able to learn the patterns within the microarray data that best determines the classification of the samples.…”
Get full text

Effects of selenium in comparison to exendin-4 on the expression of GLP-1R, IRS-1 and preproinsulin in the pancreas of diabetic rats by Rizk, Sandra

“…It binds and activates GLP-1R with greater potency than GLP-1 and is used in the treatment of diabetes mellitus. …”
Get full text
Get full text
Get full text

Trends in criminal convictions in Japan for vehicle collisions where one driver suffers from an epileptic seizure by Mineko Baba (19774386)

“…To reduce collisions to an even greater degree, this type of collision should be prevented. …”

The synthetic cathinones MDPHP and MDPV: Comparison of the acute effects in mice, in silico ADMET profiles and clinical reports by Marta, Bassi

“…Our results substantiated that MDPHP and MDPV similarly affect sensorimotor and behavioural responses in mice, importantly increased locomotion and induced aggressive behaviour, and, at higher dosage, increased heart rate and blood pressure. …”
Get full text
Get full text
Get full text

Vitamin D Association With Macrophage-Derived Cytokines in Polycystic Ovary Syndrome: An Enhanced Risk of COVID-19 Infection? by Abu Saleh Md Moin (6189512)

“…Vitamin D deficiency was associated with decreased CD80 and IFN-γ in PCOS and IL-12 in both groups (p<0.05). …”

Effects of COVID-19 on Autism Spectrum Disorder in Qatar by Fouad A. Alshaban (17281108)

“…Parents also reported decreased access to family and social support networks, as well as decreased quality of clinical and community support. …”

Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death by Tohme, Sara

“…This is followed by an increase in lipid peroxidation which peaks at later timepoints and varies between different cell lines. …”
Get full text
Get full text
Get full text

The Triple “S” Impact of COVID-19: Nationwide Evidence of the Impact of the Stress Associated With Restrictive Measures on Substance Use, Sleep, and Social Connectedness in Qatar... by Muna Abed Alah (18171346)

“…Of tobacco users in our sample, 36% reported increased tobacco use since the start of home confinement, while 41.6% of alcohol users reported decreased alcohol use. Concerning sleep, 46.1% reported an increase in average sleep duration per day (0.77 h mean increase, 95% CI: 0.66-0.88, P<0.001), and a third of participants reported poorer sleep quality. …”

Independent and Combined Effects of Antioxidant Supplementation and Circuit Resistance Training on Selected Adipokines in Postmenopausal Women by Ayoub Saeidi (17331085)

“…Participants in experimental groups either performed CRT (3 sessions per week with intensity at 55% of one-repetition maximum) or supplemented with Zataria Multiflora (500 mg every day after breakfast with 100 ml of water), or their combination, for 8 weeks. …”

Do Older Adults with Multimorbidity Meet the Recommended Levels of Physical Activity? An Analysis of Scottish Health Survey by Ahmad Salman (3173418)

“…Also, meeting recommended PA decreased with age [OR 0.92 (95% CI 0.90–0.94)] and body mass index [OR 0.93 (95% CI 0.91–0.95]; but increased per additional portion of fruit and vegetables taken [OR 1.19 (95% CI 1.12–1.25)] and with increase in well-being scale score [OR 1.05 (95% CI 1.03 to 1.06)]. …”

EVALUATION OF MATERIAL NONLINEARITY IN FATIGUED SAMPLES USING AN IMPROVED LAMB-WAVE NONLINEAR PARAMETER by A. Masurkar, Faeez

“…The material nonlinearity is also evaluated using a Physics based nonlinear parameter that depends on the second and third order nonlinear elastic constants and is independent of the propagation distance thereby giving the global material nonlinearity. It is found that for a pristine state, the peak of amplitude-based parameter equals the physics based one and for a fatigued state, the amplitude-based parameter keeps increasing with an increase in fatigue damage. …”
Get full text

The Global Economic crisis & organisation change: case studies in the UAE by Al Hashemi, Khalid

“…All of these elements should tie together in order to assure the existence of the company as a main target & then the expansion of the operation which means an increase in the profit. …”
Get full text

Clinical characteristics and outcome of children with acute cryptorchid testicular torsion: A single-center, retrospective case series study by Zlatan Zvizdic (9212371)

“…Preoperative color Doppler ultrasonography revealed absent or decreased testicular blood flow in the affected testes in 7/8 of patients. …”

COVID-19 biomarkers for severity mapped to polycystic ovary syndrome by Abu Saleh Md Moin (6189512)

“…These protein panels target biological processes involved in vessel damage, platelet degranulation, the coagulation cascade and the acute phase response [1], with greater protein changes dependent on the COVID-19 severity. …”

Chronic reduction of store operated Ca²⁺ entry is viable therapeutically but is associated with cardiovascular complications by Fang Yu (156838)

“…The hypertension is not due to increased vascular smooth muscle contractility or vascular remodelling.…”

Hypothetical high-surface-area carbons with exceptional hydrogen storage capacities by Kuchta, Bodgan

“…(iv) Additional increase of hydrogen uptake could potentially be achieved by chemical substitution and/or intercalation of OCF structures, in order to increase the energy of adsorption. …”
Get full text
Get full text
Get full text
Get full text