G9a-mediated repression of CDH10 in hypoxia enhances breast tumour cell motility and associates with poor survival outcome حسب Francesco Casciello (18557613)

"…CDH10 overexpression significantly reduces cellular movements in breast cancer cell lines and prevents the hypoxia-mediated increase in cell motility. …"

The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function حسب MUBARAK, ALIA MARJAN

"…These mega-projects may include the construction of major buildings, roads, railway lines and airports. The success of these public initiatives may create the course for the government to decrease its reliance on other sectors. …"
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Control of TGFβ signalling by ubiquitination independent function of E3 ubiquitin ligase TRIP12 حسب Kripa S Keyan (10644815)

"…Instead, <i>TRIP12</i> recruits SMURF2 to SMAD4, which is most likely responsible for inhibitory monoubiquitination of SMAD4, since SMAD4 monoubiquitination and its interaction with SMURF2 were dramatically downregulated in <i>TRIP12</i>^<em>-</em>^/- cells. …"

Patients’ Perspectives About Factors Affecting Their Use of Electronic Personal Health Records in England: Qualitative Analysis حسب Alaa Abd-Alrazaq (17430900)

"…There are practical considerations that, if incorporated into the system, are likely to improve its adoption rate: Patient Online should be useful, easy to use, secure, and easy to access. …"

The Study of Maternal Factors and Their Association with Risk of Preterm Birth حسب Alaa Al-Naama (17075063)

"…We hypothesize that certain maternal factors increase the risk of PTBs.</p> <h3>Design</h3> <p>A retrospective study recruiting women in labor at WWRC from June 2022 until February 2023.…"

Impact of the COVID-19 lockdown on lifestyle behaviors and their association with personality among adults in Qatar: A cross-sectional study حسب Tamara Al-Abdi (8710488)

"…Openness was positively associated with all PA (<i>p </i>= 0.027), including walking (<i>p </i> = 0.026), and negatively associated with sitting (<i>p </i> = 0.038) before lockdown, while participants with high scores for neuroticism were less likely to be sitting during lockdown (<i>p </i> = 0.042). …"

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co... حسب Alize J, Ferrari

"…Globally between 2010 and 2021, the age-standardised DALY rates for HIV/AIDS decreased by 47·8% (43·3–51·7) and for diarrhoeal diseases decreased by 47·0% (39·9–52·9). …"
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Computed tomography-detected hemothorax after blunt chest trauma: Does everyone need an intervention? A retrospective analysis حسب Ismail Mahmood (14150352)

"…Patients with larger hemothorax volumes were significantly more likely to require tube thoracostomy (<i>p</i> = 0.001) and had significantly longer hospital stays (<i>p</i> = 0.021). …"

Investigating the incidence, nature, severity and potential causality of medication errors in hospital settings in Qatar حسب Binny Thomas (5801969)

"…Effort is required to increase the effectiveness and efficiency of the reporting system. …"

Hurdling the Challenges of the 2019 IAAF World Championships حسب Olivier Girard (409080)

"…In particular, athletes are likely to encounter challenging hot temperatures and potentially high humidity levels that may eventually impair performance during middle and long distance events and increase the risk of exertional heat. …"

A single-institution review of 157 patients presenting with benign and malignant tumors of the ampulla of Vater حسب Azar, Riad

"…We anticipate that the debate on the roles of surgery and endoscopy in the treatment of small cancerous tumors will likely increase as experience with endoscopic resection increases. …"
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Road deaths and injuries in India: Action required on the five pillars of road safety حسب Gopalakrishna Gururaj (19807233)

"…While urban deaths account for nearly a fifth of total deaths and injuries, Indian highways account for more than 50% of deaths and injuries and are likely to increase with further growth in infrastructure (1). …"

Genomic architecture of autism spectrum disorder in Qatar: The BARAKA-Qatar Study حسب Mona Abdi (10196665)

"…Moreover, homozygous variants were found in 7 families (25.9%), with a sixfold increase in homozygous burden in consanguineous versus non-consanguineous families (13.6% and 1.8%, respectively). …"

Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) حسب Azar, Daniel Fadi

"…Furthermore, we have attempted to examine the photochemical potential of our metal-organic compound model by combining L-II and L-III in the same metal complex, thus generating four final complexes with differing net charges (from +2 to -4), and examining their activities on a panel of AML cell lines with or without exposure to blue light. Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …"
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Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019 حسب Hedyeh Ebrahimi (7321358)

"…Global age-standardised incidence rates of tracheal, bronchus, and lung cancer decreased by 7·4% (−16·8 to 1·6) and age-standardised incidence rates of larynx cancer decreased by 3·0% (−10·5 to 5·0) in males over the past decade; however, during the same period, age-standardised incidence rates in females increased by 0·9% (−8·2 to 10·2) for tracheal, bronchus, and lung cancer and decreased by 0·5% (−8·4 to 8·1) for larynx cancer. …"

Holistic Transitional Approach of Humanitarian Shelters Through The Implementation of Adaptable Design Strategies. حسب ALSHALABI, WASEEM

"…The issue of forcibly displaced portions of a population has become an emerging global trend that is driven by significantly increased numbers of displaced people. This is caused by increases in natural disasters due to global warming, war, and other conflicts. …"
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Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 حسب Natalia V, Bhattacharjee

"…The share of livebirths was projected to decline between 2021 and 2100 in most of the six other super-regions—decreasing, for example, in south Asia from 24·8% (23·7–25·8) in 2021 to 16·7% (14·3–19·1) in 2050 and 7·1% (4·4–10·1) in 2100—but was forecast to increase modestly in the north Africa and Middle East and high-income super-regions. …"
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New media and new practices of exploitation حسب Uzunoglu, Sarphan

"…Today, in new media sphere, tracking technologies replaced rating systems and data about consumer is being sold. Increasing use of new media and increasing Internet penetration through rising sales numbers of mobile devices caused a necessity for a new debate. …"
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Global, regional, and national prevalence of adult overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021 حسب Marie, Ng

"…Assuming the continuation of historical trends, by 2050, we forecast that the total number of adults living with overweight and obesity will reach 3·80 billion (95% UI 3·39–4·04), over half of the likely global adult population at that time. While China, India, and the USA will continue to constitute a large proportion of the global population with overweight and obesity, the number in the sub-Saharan Africa super-region is forecasted to increase by 254·8% (234·4–269·5). …"
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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... حسب Michael, Brauer

"…For younger demographics (ie, those aged 0–4 years and 5–14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …"
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