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941
Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway
Published 2021“…SNG treatment increased Bax/Bcl-2 ratio, which contributed to a leaky mitochondrial membrane leading to cytochrome c release accompanied by caspase activation. …”
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942
A possible culprit for refractory angina
Published 2015“…</p><p>This may implicate lipoprotein(a) as having a causal role in refractory angina, but the findings still need to be confirmed by testing a control group of patients who have coronary heart disease but not refractory angina.</p><p>An increased lipoprotein(a) level is known to be highly heritable, and is believed to promote hardening of the arteries by trapping cholesterol in the inner linings of blood vessels, promoting clot formation, recruiting inflammatory cells, or binding pro-inflammatory phospholipids.…”
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943
High fractional excretion of glycation adducts is associated with subsequent early decline in renal function in type 1 diabetes
Published 2020“…<div><p>Increased protein glycation, oxidation and nitration is linked to the development of diabetic nephropathy. …”
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944
Exploring the Effect of [HuArgI (Co)-PEG5000]-Induced Autophagy on the Migration, Adhesion, and Invasion of A172 Glioblastoma Cells
Published 2024“…Our results show that arginine deprivation significantly activates autophagy in A172 cells, as evidenced by increased autophagosome formation and LC3-II/LC3-I ratios. …”
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945
The Influence of Risks on the Success of the Development and Installation of Temporary Structure in Event Projects in Dubai
Published 2017“…The number of events in Dubai is getting increased and the temporary structures have been widely used as a mandatory element to support the event’s venue whether to expand the capability of the venue or to create the ambience for the event. …”
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946
Struvite Recovery from Anaerobically Digested Dairy Manure: A Review of Application Potential and Hindrances
Published 2016“…Struvite formation and purity is likely a function of all the interfering variables, rather than just a single factor with digested dairy manure. …”
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947
A new method for broad‐scale modeling and projection of plant assemblages under climatic, biotic, and environmental cofiltering
Published 2023“…<p></p><div> <p>There is increasing interestin broad-scale analysis, modeling, and prediction of the distribution and composition of plant species assemblages under climatic, environmental, and biotic change, particularly for conservation purposes. …”
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948
Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice
Published 2015“…Throughout the 14 weeks of the model, tumor burden increased in homozygous Mmp8-null mice compared to Mmp8-wild-type and -heterozygote animals. …”
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949
Impact of timing and severity of COVID-19 infection in pregnancy on intrauterine fetal growth- a registry-based study from Doha-Qatar
Published 2023“…<h3>Background</h3> <p>The novel coronavirus disease (COVID-19) pandemic has impacted pregnant women, increasing maternal and neonatal morbidity. The placenta is a potential target for the pathophysiological processes due to the increased thrombotic inflammatory activation and inadequate uteroplacental perfusion and oxygenation, potentially causing intrauterine growth restriction. …”
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950
Postprandial Insulin and Triglyceride Concentrations Are Suppressed in Response to Breaking Up Prolonged Sitting in Qatari Females
Published 2019“…Additionally, there was a most likely “moderate” lower tAUC (-0.63 ± 0.37), iAUC (-0.91 ± 0.49), and positive AUC (-0.91 ± 0.49) for triglycerides in WALK compared to SIT. …”
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951
Epidemiology of extended-spectrum beta-lactamase producing Enterobacteriaceae in Qatar: A 3-year hospital-based study
Published 2022“…<h3>Background</h3><p dir="ltr">The incidence of ESBL infections is exponentially increasing with variable prevalence among geographical areas and treatment settings. …”
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952
The SREBP-dependent regulation of cyclin D1 coordinates cell proliferation and lipid synthesis
Published 2022“…Consequently, inactivation of SREBP1 in human liver and breast cancer cell lines reduces the expression of cyclin D1 and attenuates Rb phosphorylation. …”
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953
Optimizing microgrid efficiency: Coordinating commercial and residential demand patterns with shared battery energy storage
Published 2024“…Moreover, considering DTR for transmission lines, instead of fixed thermal rating, improves the PAR and DPS up to 28.52 % and 41.06 % respectively. …”
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954
Knowledge gap hypothesis and pandemics: Covid-19 knowledge, communication inequality, and media literacy in Lebanon
Published 2023“…The evidence shows a widening of the knowledge gap for those more likely to post on social media and a narrowing of the knowledge gap for those more exposed to social media news, but the observed narrowing of the knowledge gap for television exposure was not statistically generalizable. …”
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955
Conflict in Ukraine and the unsettling ripples: implications on food systems and development in North Africa
Published 2024“…Algeria) will likely be able to mitigate the adverse effects on their citizens. …”
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956
An exploration of intelligence management opportunities for organizations in the UAE: Possible challenges for culture
Published 2017“…The aim of this paper was to explore the intelligence management opportunities available to Organizations operating within the UAE market, and the likely impact of the UAE culture on Such businesses. …”
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957
Effect of Surgical Margin Status on Survival and Site of Recurrence After Hepatic Resection for Colorectal Metastases
Published 2005“…Patients with positive margins were more likely to have surgical margin recurrence (P = 0.003). …”
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958
In search of immune cellular sources of abnormal cytokines in the blood in autism spectrum disorder: A systematic review of case-control studies
Published 2022“…Cytokines IFN-<b>γ</b>, TGF-β, RANTES, and IL-8 were increased in the plasma/serum of subjects with autism, and IFN-<b>γ</b> was likely produced by CD4+ T cells and natural killer (NK) cells, although conflicting evidence is present for IFN-<b>γ</b> and TGF-β. …”
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959
The ras/cAMP-dependent protein kinase signaling pathway regulates an early step of the autophagy process in saccharomyces cerevisiae
Published 2004“…Quantitative assays indicate that these increased levels of Ras/PKA signaling activity result in an essentially complete block to autophagy. …”
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960
Roles of the pharmacist in the use of safe and highly effective long‐acting reversible contraception
Published 2014“…Women are more likely to use LARC methods when barriers such as access and cost are removed. …”
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