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The Anti-Proliferative and Pro-apoptotic Effect of Topotecan in Combination With Thymoquinone in Acute Myelogenous Leukemia
Published 2014“…Topotecan (a novel topoisomerase I inhibitor and a water-soluble camptothecin analog) is active against numerous human tumor cell lines, and has shown promising antineoplastic activity in solid tumors and acute leukemia. …”
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RFX3 is essential for the generation of functional human pancreatic islets from stem cells
Published 2025“…</p><h3>Methods</h3><p dir="ltr">We generated <i>RFX3 </i> knockout (<i>RFX3 KO</i>) iPSC lines using CRISPR/Cas9 and differentiated them into pancreatic islet organoids. …”
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Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
Published 2020“…However, when accounting for ageing and population growth, declines were observed in age-standardised prevalence (14·3% decrease), age-standardised death rates (42·6%), and age-standardised DALY rates (38·2%). …”
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“Your taste in fashion is bad”: The role of state of anger in aggressive behavior using the hot sauce paradigm
Published 2020“…<p dir="ltr">This study investigates a mediator of the link between anger induction and subsequent aggressive behavior: the state of anger. …”
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INTEGRATING TRADITIONAL AND UNCONVENTIONAL CSR THEORIES AND MODELS – A THEORETICAL
Published 2020“…The surge in financial scandals, widening gaps in social inequality, increasing political and financial muscle by MNC’s, global uncertainties as well as environmental degradation has put the spotlight on firms to strengthen their involvement and be sensitive to socially responsible activities. …”
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Enterprise risk management in healthcare organizations
Published 2021“…Organizational Risk Management (ERM) emerged as a new approach for managing organizational risks, concentrating on mechanisms to increase corporate governance and risk management in a holistic manner across many enterprise domains. …”
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Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches
Published 2018“…Periodic based automatic cleaning showed decreases in improvement of between 164.64% to 245.34%. …”
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Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults
Published 2022“…Objective: According to the World Health Organization (WHO), depression is the main cause of disability worldwide and high risk was noticed in Saudi Arabia. The link between nutrition and mental health has been extensively studied in recent years. …”
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The Candida albicans Hwp2 is necessary for proper adhesion, biofilm formation and oxidative stress tolerance
Published 2011“…It appears that Hwp2 is necessary for proper oxidative stress tolerance, adhesion and biofilm formation as an hwp2 null is more susceptible to increasing doses of hydrogen peroxide, unable to adhere efficiently to epithelial and endothelial cell lines and unable to form wild type biofilm levels.…”
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Occupational exposure assessment for power frequencyelectromagnetic fields
Published 1997“…The agents of interest in this case are the electric and magnetic fields (EMF) in the extreme low frequency range that includes the power frequency of 50/60 Hz. There are an increasing concern that exposure to EMF may be associated with biological and health effects. …”
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Assessing Struvite Formation Potential at Wastewater Treatment Plants
Published 2012“…Wastewater treatment plants, especially those employing secondary treatment and anaerobic sludge digestion, have historically encountered phosphate precipitates, one of the commonest being struvite, that foul and encrust the sludge return lines, and the associated pumps and valves. This growth of ‘uncontrolled’ struvite increases pumping and maintenance cost, as well as reduces the overall capacity of the plant piping system in terms of lost hydraulic capacity and lowered biological treatment capacity. …”
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336
Supplementation of retrobulbar block with clonidine in vitreoretinal surgery
Published 2011“…The median number of postoperative analgesic requests per patient during the first 24 hours was higher in the control group than the clonidine group [2 (0-3) vs. 1 (0-3); P < 0.001]. …”
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Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function
Published 2017“…Over-expression of MMP-8 WT but not MMP-8 EA in β6-1089 cells increased adhesion to ECM proteins and reduced migration. …”
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The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe
Published 2023“…This research indicates a positive correlation between living alone and loneliness, with a greater effect on males, and identifies loneliness as an independent factor decreasing QoL. …”
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Carotid artery revascularization through a radiated field
Published 2003“…Follow-up duplex scans showed asymptomatic recurrent stenosis greater than 60% in 3 patients, 2 of whom with stenosis greater than 80% underwent repeat operation. …”
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