The mechanisms of resistance of anthrax lethal toxin (LeTx)-induced cytotoxicity in AML cells. (c2018) حسب Abou Harb, Monica

"…Our results indicate that vertical inhibition by SCH772984 rendered the resistant cell lines sensitive to the inhibition of the MAPK-pathway and showed an increased cytotoxic effect once used in combination with anthrax lethal toxin compared to the use of anthrax lethal toxin alone.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The role of methanolic extract of Quercus infectoria bark in lipemia, glycemia, gastric ulcer and bacterial growth حسب Khouzami, L.

"…After one month of chronic extract (0.5% w/v) intake via drinking water, there was a significant increase in serum HDL-cholesterol level. This was accompanied with an increase in both serum glucose and insulin levels. …"
احصل على النص الكامل
احصل على النص الكامل

The July war and its effects on Lebanon’s power-sharing حسب Fakhoury, Tamirace

"…On a broader scale, this article helps shed light on the dilemma of power-sharing systems on stormy seas when external conflicts overlap with internal conflict lines.…"
احصل على النص الكامل

Effectiveness of communication processes in Agile Project Management Approach in the UAE Utility Sector حسب AFIFI, MUTASIM ABDALLA HASSAN

"…Team members should have a voice in the agile project management process, maintain open lines of communication with stakeholders, and discuss problems in a timely manner to increase tolerance and acceptance.…"
احصل على النص الكامل

The effects of Salvia Officinalis leave on hyperlipidemia, glycemia, ulcer, inflammation, and bactericidal activity. (c2006) حسب Alayan, Iman

احصل على النص الكامل
احصل على النص الكامل

Economic Diplomacy And Its Effect On Trade حسب Al Hajri, Rashid Ghanem

احصل على النص الكامل

Effect of Construction Void Defects on Flexural and Axial Load Capacity of Reinforced Concrete Members حسب Al Moukdad, Mohammad Mustafa

احصل على النص الكامل

Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes حسب Rizk, Sandra

"…The percent reduction in proliferation was very significant, and was dose-, and time-dependent. In both cell lines, kefir exhibited its antiproliferative effect by downregulating TGF-α and upregulating TGF-β1 mRNA expression. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The Russia-Ukraine war, soaring food prices, and the Turkish economy: insights from computable general equilibrium حسب Ozcan Ozturk (14606326)

"…Türkiye, as a neighboring country and a major player in the region, maintains close ties with Ukraine and Russia and heavily relies on agricultural imports from both countries making it susceptible to market shocks caused by the war. …"

Exercise-induced a-ketoglutarate enhances spatial learning by modulating hippocampal levels of BDNF in a sex-specific manner حسب Al Ahmad, Perla

"…Exercise promotes the release of proteins and metabolites known as exercise factors from the muscles, liver, and bones into the blood. The exercise factors increase hippocampal levels of brain-derived neurotrophic factor (BDNF) which mediates the benefits of exercise on cognition. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Environmental enrichment and cafeteria diet synergistically modify the response to chronic variable stress in rats حسب Zeeni, Nadine

"…The effects of stress, EE and diet on animal adiposity, serum lipids, and stress hormones were analyzed. Results showed increases in liver weight and intra-abdominal fat associated with the CAF diet and an increase in bodyweight gain associated with both the CAF diet and EE. …"
احصل على النص الكامل
احصل على النص الكامل

The Anti-Tumor Effect of Flaxseed Lignan Derivatives on Different Acute Myeloid Leukemia Cancer Cells حسب Tannous, Stephanie

"…Moreover, Cell Death ELISA analysis showed a dose-dependent increase in apoptosis, as revealed by an increase in DNA fragmentation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The Impact of Sporting Events on Air Pollution: An Empirical Examination of National Football League Games حسب Nicholas Watanabe (19450285)

"…From this, multiple regression analysis was utilized to estimate whether the number of fans was related to changes in air pollution. (3) Results: The regression models found that Ozone and Nitrogen Dioxide levels increased as more individuals attended NFL games. Additional robustness checks and falsification tests suggest that the average NFL event results in an approximately two-percent increase in Ozone levels. (4) Conclusions: The findings from this study contribute to the literature by providing evidence that highly attended sporting events increase pollution levels in the areas near stadiums. …"

Parallel multi-voltage power minimization in VLSI circuits. (c2013) حسب Younes, Rabih Halim

احصل على النص الكامل
احصل على النص الكامل

Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) حسب Azar, Daniel Fadi

"…Furthermore, we have attempted to examine the photochemical potential of our metal-organic compound model by combining L-II and L-III in the same metal complex, thus generating four final complexes with differing net charges (from +2 to -4), and examining their activities on a panel of AML cell lines with or without exposure to blue light. Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …"
احصل على النص الكامل
احصل على النص الكامل

Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells حسب Tawil, Mirna

"…In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute... حسب Farhat, Mirna

"…However, given that MMP9 was found not to be expressed in the sensitive cell lines, we were able to exclude its expression as a requirement for cytotoxicity. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The effects of daucus carota extracts on different body functions, inflammation, induced gastric ulcer in rats and bacterial growth. (c2005) حسب Abdallah, Katia Wehbe

احصل على النص الكامل
احصل على النص الكامل

Impacts of On-Grid Solar PV on Distribution Networks and Potential Solutions: A Case Study in the Region of Zahle حسب Korkmaz, Jessica

"…Recent years have witnessed an increase in the installation of solar photovoltaic-based distributed generators or PV DGs mainly in countries with high solar potential such as Lebanon. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…The pro-apoptotic effect upon combination of topotecan with andrographolide was further observed using annexin V/PI staining; even though andrographolide alone did not alter cell survival, however, when applied to the cells prior to topotecan treatment, the number of apoptotic cells increased from 16% to 57%. Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل