Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation حسب Shilpa Kuttikrishnan (3520079)

"…Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …"

Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3 حسب Harshita Shailesh (14779408)

"…<p></p><div> <p>Protein arginine methyltransferase 5 (PRMT5) activity is dysregulated in many aggressive cancers and its enhanced levels are associated with increased tumour growth and survival. However, the role of PRMT5 in breast cancer remains underexplored. …"

Inositol 1,4,5-Trisphosphate Receptors in Hypertension حسب Ali H. Eid (5461829)

"…This involves a phenotypic switch of VSMCs as well as an alteration of cytoplasmic Ca²⁺ signaling machinery, a phenomena tightly related to the aging process. Several lines of evidence implicate changes in expression/function levels of IP₃R isoforms in the development of hypertension, VSMC phenotypic switch, and vascular aging. …"

Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway حسب Kirti.S. Prabhu (17191231)

"…SNG treatment increased Bax/Bcl-2 ratio, which contributed to a leaky mitochondrial membrane leading to cytochrome c release accompanied by caspase activation. …"

Emergency ultrasound training needs review حسب Nature Research (16552612)

"…Residents’ level of confidence also increased with increased years of experience for all types of sonography except for scanning first trimester pregnancies. …"

Solar syngas production via methanothermal reduction of strontium oxide حسب Rahul R. Bhosale (6467102)

"…Application of heat recuperation considerably decreased the requirement of solar energy input, and hence the process efficiency is further amplified. …"

Potent anti-tumor promoting effects of Daucus carota oil extract in mice حسب Abou Zeinab, RM

"…Inraperitoneal treatment inhibited tumor yield by 43%, and decreased the tumor volume by 85% at week 20. Gavage treatment failed to inhibit the promotion of tumors but decreased tumor volume by 20%. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The global, regional, and national burden of colorectal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global B... حسب Saeid Safiri (3713035)

"…Globally, colorectal cancer accounted for 896 000 (876 300–915 700) deaths in 2017, with an age-standardised death rate of 11·5 (11·3–11·8) per 100 000 person-years, which decreased between 1990 and 2017 (−13·5% [–18·4 to −10·0]). …"

Effect of chronic and non-chronic moderate wine consumption upon rat lipoprotein profile in the blood. (c2002) حسب Slaiby, Rita

احصل على النص الكامل
احصل على النص الكامل

Ultrasound‑triggered herceptin liposomes for breast cancer therapy حسب Elamir, Amal

"…Exposing the liposomes to low-frequency ultrasound (LFUS) triggered drug release which increased with the increase in power density. Trastuzumab conjugation resulted in enhancing the sensitivity of the liposomes to LFUS. …"
احصل على النص الكامل

Assessment of High-resolution Local Emissions and Land-use in Air Quality Forecasting at an Urban, Coastal, Desert Environment حسب Christos Fountoukis (4722963)

"…The model’s forecast accuracy was assessed against measurement data from five ground air quality monitoring stations in the greater metropolitan area of Doha over a one-month period. …"

The Effects of Online Formative and Summative Assessment on Test Anxiety and Performance: A Study Among First-Year Undergraduate Students at A Higher Education Institution in Abu D... حسب ALSUWAIDI, MUNA

"…The presented study was conducted to provide greater insight into the potential positive, neutral and/or negative effects of online formative and summative assessment on test anxiety and performance. …"
احصل على النص الكامل

Brucellosis in older person: a case report from Qatar حسب Hanadi Khamis Al Hamad (21406964)

"…Anemia and raised CRP and liver enzymes were the most prominent laboratory abnormalities in our patients. …"

Composite hydrogels from carrageenan-cl-carboxymethyl chitosan–PVA incorporated ZiF-8 as dressing material for wound healing applications حسب Tooba Yasin (19131382)

"…The biocompatibility of the composite hydrogels has been evaluated using fibroblast cell lines (<i>3T3</i>) after different time intervals (24–72 h), and it was found that increasing ZiF-8 caused the mature and spread cell morphology with increasing cell viability and proliferation under controlled in vitro conditions. …"

Optimizing microgrid efficiency: Coordinating commercial and residential demand patterns with shared battery energy storage حسب Mohammadreza Gholami (17032317)

"…In response to the increasing integration of BESS in modern energy systems, this study investigates the implications of incorporating BESS within connected residential-commercial Microgrids (MGs). …"

Developing a Hybrid Model for Network Planning in Abu Dhabi Distribution Company Subsidiary of Adwea حسب Al Haddabi, Aseya Mohammed

احصل على النص الكامل

Effect of nickel loading on hydrogen production and chemical oxygen demand (COD) destruction from glucose oxidation and gasification in supercritical water حسب Youssef, Emhemmed A.

"…Results also showed that the presence of Ni increased the total gas yield increased in the 7.5–18 wt Ni/Al2O3 catalyst. …"
احصل على النص الكامل

Type 2 Diabetes Mellitus Automated Risk Detection Based on UAE National Health Survey Data: A Framework for the Construction and Optimization of Binary Classification Machine Learn... حسب Mohamed, AlShuweihi

"…This research motivated by the unprecedented increase in diabetes and specifically Type 2 Diabetes Miletus (T2DM), proposes two significant contributions. …"
احصل على النص الكامل

Associating learning technology to sustain the environment through green mobile applications حسب Haraty, Ramzi A.

"…With “quality education” a major issue for the UN 2030 Sustainable Development Agenda, it is a must that we loop together the “quality education” with education per se. It is imperative that we engage the youth in attaining this objective, for it is not enough that we empower them with the tools, we must encourage them to look at the current issues outside the box, through a worldwide view, where the focus nowadays is on the environment, be it in reducing fuel usage, decreasing air and water pollution, and recycling, in brief, being environment friendly. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Acute pain management and assessment حسب Zeitoun, Abeer A.

"…Appropriateness of pain management was determined as per World Health Organization guidelines. Institutional Review Board approvals were obtained from each hospital. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل