Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases by Glazer, Evan

“…For example, a few years ago an extrahepatic metastasis effectively eliminated surgical resection, but a combination of chemotherapeutic options and surgical techniques has expanded the indications for resection and increased the population of patients who may benefit.1,2 Neoadjuvant chemotherapy has increased the resectability rate by 11% to 37%.1 Unfortunately, greater than 80% of patients undergoing hepatic resection will have recurrences, mostly within the first 2 years.2 Nonetheless, the only hope for cure is resection, and prior surgical dogma based on the number of lesions, size of the tumor-free resection margin, and presence of resectable extrahepatic disease must be questioned.3- 5 The current standard approach to surgical planning is contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) for specific tumor characteristics or contraindications to CT.6 Several series showed that focal extrahepatic disease, an isolated pulmonary lesion, can be safely resected, with 5-year survival rates of 29% to 58%.7,8 In 1 series,7 17 of 30 patients required 3 or more resections. …”
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A marking technique for intraoperative localization of small liver metastases before systemic chemotherapy by Zalinski, Stephanie

“…Preoperative chemotherapy is increasingly used prior to resection of colorectal liver metastases (CLM). …”
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Repeat hepatectomy for recurrent colorectal liver metastases is associated with a high survival rate by Andreou, Andreas

“…Background:  The outcome after a repeat hepatectomy for recurrent colorectal liver metastases (CLM) is not well defined. The present study examined the morbidity, mortality and long-term survivals after a repeat hepatectomy for recurrent CLM. …”
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Body surface area and body weight predict total liver volume in Western adults by Vauthey, Jean-Nicolas

“…Computed tomography (CT) is used increasingly to measure liver volume in patients undergoing evaluation for transplantation or resection. …”
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Artificial Intelligence for Detecting and Quantifying Fatty Liver in Ultrasound Images: A Systematic Review by Fahad Muflih Alshagathrh (18427950)

“…Conclusion: AI-supported systems show potential performance increases in detecting and quantifying steatosis, NASH, and liver fibrosis in NAFLD patients. …”

Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines by Najlah, Mohammad

“…The zeta potential of linoleic had a greater negative value than that of Intralipid.Loading efficiencies for paclitaxel were 70.4–80.2% and 44.2–57.4% for Clinoleic and Intralipid formulations, respectively. …”
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From Waste Reduction to Worker Comfort: Leveraging Lean Manufacturing and Ergonomics in Textiles Sewing Industries in UAE by ALAM, SAUD AMIR

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Metformin Induces Different Responses in Clear Cell Renal Cell Carcinoma Caki Cell Lines by Mazhar Pasha (11197767)

“…Our findings demonstrate a differential response between the two ccRCC cell lines studied, with Caki-2 cells being more sensitive to metformin compared to Caki-1 cells, which could be linked to the differential expression of HIF-1 despite both cell lines carrying a wild-type VHL. …”

Bound by barriers: demystifying the constraints on an elevated Kuwait-Türkiye co-operation in the defence realm by Ali Bakir (17917703)

“…First, Kuwait is less inclined to enhance its security and defence ties with Türkiye compared to the UAE, Qatar, and Saudi Arabia. …”

Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model by Haissam Abou-Saleh (497840)

“…Although no single sign of cardiotoxicity was observed upon exposure to 200 mg/L of ChNPs, as judged by heartbeat rate, the corrected QT interval (QTc, which measures the time between the start of the Q wave and the end of the T wave in the heart's electrical cycle), maximum cardiac arrest, and ejection fraction assays, the same dosage elicited the impairment of both liver size (decreased liver size, but without steatosis and lipid yolk retention) and neurobehavioral activity (increased movement under different light conditions). …”

Novel Platinum II and Platinum IV Complexes Exhibit An Anti-Neoplastic Potential Against A549 Cancer Cell Line by Baz, Joy

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Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles by El Maarri, Osman

“…However, the previously reported increase of LINE-1 methylation in males was reconfirmed. …”
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Assessment of tropospheric NO₂ concentrations over greater Doha using Sentinel-5 TROPOspheric monitoring instrument (TROPOMI) satellite data: Temporal analysis, 2018–202... by Yasir E. Mohieldeen (22155901)

“…<p dir="ltr">This study presents a temporal evaluation of the tropospheric NO₂ column densities over Greater Doha using TROPOMI satellite data from May 2018 to December 2023, and an assessment of the impact of the preparations and hosting of the FIFA Football World Cup Qatar 2022, on NO₂ levels before, during and after the tournament over Greater Doha. …”

Effects of lipid administration on liver apoptotic signals in a mouse model of total parenteral nutrition (TPN) by Btaiche, Imad

“…Interestingly, we have recently observed an increase in hepatocyte apoptosis with administration of TPN. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells by Shebaby, Wassim N.

“…Methods and results Using the WST assay, the pentane fraction (F1) and 1:1 pentane:diethyl ether fraction (F2) were shown to possess the highest cytotoxicity against both cell lines. Flow cytometric analysis revealed that both fractions induced the accumulation of cells in the sub-G1 phase, increase in apoptotic cell death and chromatin condensation. …”
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A comparative study of the antiproliferative effect of kohlrabi and green cabbage on colorectal cancer cell lines. (c2012) by Zarzour, Valia M.

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The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis by Mroueh, MA

“…PI/Annexin staining also showed an increase in apoptosis in cells treated with PF. Western blot analysis of several apoptotic proteins also proved a direct activation of PF of the apoptotic pathway in cancer cells. …”
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Performance analysis of power line communication systems with diversity combining under correlated lognormal fading and Nakagami noise by Abou-Rjeily, Chadi

“…In this study, the authors evaluate the bit error rate (BER) performance of multichannel power line communication (PLC) systems under lognormal fading and Nakagami-m background noise. …”
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Efficacy and safety of aldafermin in non-alcoholic steatohepatitis: A systematic review and meta-analysis of randomized controlled trials by Mohamed Mahmoud Marey (18560902)

“…<h3>Background</h3><p dir="ltr">Non-alcoholic steatohepatitis (NASH) is an advanced subtype of non-alcoholic fatty liver disease (NAFLD). NASH prevalence is increasing exponentially and carries a high risk for disease progression, cirrhosis, and liver-related mortality. …”

Novel proteins implicated in lipid metabolism disorders by Nature Research (16552612)

“…</p><p>ANGPTL3 is a protein secreted by the liver, belonging to the angiopoietin-like family of eight proteins. …”