يعرض 221 - 240 نتائج من 2,051 نتيجة بحث عن '(( greater decrease ) OR ((( (time OR (like OR lines)) increase ) OR ( per decrease ))))*', وقت الاستعلام: 0.14s تنقيح النتائج
  1. 221
  2. 222

    Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute... حسب Farhat, Mirna

    منشور في 2023
    "…Finally, while IMC/LF treatment did not affect the expression of any of the proteases tested (uPAR, MMP2, and MMP9), treatment with IMC/FP59 did affect their expression with significant cytotoxic responses seen only in cells whose uPAR expression was not affected at any time point post-treatment. In this study, we showed for the first time the potency of IMC PrAg variant on AML cell lines, its mode of action, as well as its mechanism of cell death.…"
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    masterThesis
  3. 223
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    Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) حسب El Jawhari, Yassmine

    منشور في 2018
    "…The addition of chloroquine, an autophagy inhibitor, increased the sensitivity of cells to [HuArgI (Co)-PEG5000]-mediated arginine depletion at earlier time points. …"
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    masterThesis
  5. 225

    The Anti-Tumor Effect of Flaxseed Lignan Derivatives on Different Acute Myeloid Leukemia Cancer Cells حسب Tannous, Stephanie

    منشور في 2020
    "…Cytotoxicity assays, using WST-1, revealed dose- and time- dependent effects in various AML cell lines with the most prominent cytotoxicity exhibited by ENL. …"
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    masterThesis
  6. 226

    Characterizing the dynamics of climate and native desert plants in Qatar حسب Meshal Abdullah (17746950)

    منشور في 2024
    "…Optimal rainfall events per year ranged from 10 to 15, with 70 mm being the threshold for healthy vegetation growth. …"
  7. 227

    Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes حسب Rizk, Sandra

    منشور في 2011
    "…The percent reduction in proliferation was very significant, and was dose-, and time-dependent. In both cell lines, kefir exhibited its antiproliferative effect by downregulating TGF-α and upregulating TGF-β1 mRNA expression. …"
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    article
  8. 228
  9. 229

    Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) حسب Azar, Daniel Fadi

    منشور في 2016
    "…Furthermore, we have attempted to examine the photochemical potential of our metal-organic compound model by combining L-II and L-III in the same metal complex, thus generating four final complexes with differing net charges (from +2 to -4), and examining their activities on a panel of AML cell lines with or without exposure to blue light. Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …"
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  10. 230

    Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 حسب Letourneau, Ian D

    منشور في 2024
    "…Although the global age-standardised incidence rate of appendicitis has steadily decreased between 1990 and 2021, almost half of GBD regions saw an increase of greater than 10% in their age-standardised incidence rates. …"
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    article
  11. 231

    Modeling circadian clock–cell cycle interaction effects on cell population growth rates حسب El Khatib, N.

    منشور في 2014
    "…Particularly, we show that Cry 1, Cry 2 mutations decrease the growth rate of cells, Per 2 mutation enhances it and Bmal 1 knockout increases it for autonomous periods of the cell cycle less than 21 h and decreases it elsewhere. …"
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  12. 232

    Trade Flow and Nation Brand Distance: A Structural Gravity Model Approach حسب AL BESHER, HUDA ISMAIL

    منشور في 2021
    "…The results on the impact of NBD on FTA and trade flows provides some interesting insights as the there is a negative and significant moderation impact of NBD on the relationship between FTA and both export and import volume which suggest that a decrease of NBD will increase the effect of FTA on trade flow. …"
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  13. 233

    Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes حسب Maryam Aghadi (17128819)

    منشور في 2022
    "…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …"
  14. 234

    Impacts of On-Grid Solar PV on Distribution Networks and Potential Solutions: A Case Study in the Region of Zahle حسب Korkmaz, Jessica

    منشور في 2025
    "…Recent years have witnessed an increase in the installation of solar photovoltaic-based distributed generators or PV DGs mainly in countries with high solar potential such as Lebanon. …"
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    masterThesis
  15. 235

    Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro حسب Rizk, Sandra

    منشور في 2016
    "…The pro-apoptotic effect upon combination of topotecan with andrographolide was further observed using annexin V/PI staining; even though andrographolide alone did not alter cell survival, however, when applied to the cells prior to topotecan treatment, the number of apoptotic cells increased from 16% to 57%. Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…"
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    article
  16. 236

    ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] حسب Abdel Khalek, Maya

    منشور في 2021
    "…Secondly, the results also showed in both U251 and A172 cells, an increase in the percentage of the survival of cells co-treated with HuArgI (Co)-PEG5000 and chloroquine; indicating that autophagy is contributing to cell death at late time points in GBM cells. …"
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  17. 237
  18. 238

    Minimization of the amplitude of the entire span of beams using mass dampers حسب Issa, Jimmy S.

    منشور في 2017
    "…Since minimizing the amplitude at one point of the beam might increase it at another point, in this work the maximum amplitude along the entire beam span is minimized. …"
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    conferenceObject
  19. 239

    Do high energy-efficient buildings increase overheating risk in cold climates? Causes and mitigation measures required under recent and future climates حسب Mutasim Baba, Fuad

    منشور في 2022
    "…While without adequate ventilation, the overheating risk in high-energy-efficient buildings can be higher than old buildings, where decreasing wall and window U-values and infiltration rate has a greater contribution to the increase of indoor temperature, while decreasing window SHGC has a lower contribution to the decrease in indoor temperature compared to the case with adequate ventilation. …"
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  20. 240