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1661
The Prevalence and Factors Associated with Low Back Pain Among People with Flat Feet
منشور في 2021"…Results The prevalence of LBP among participants with flat feet was 65.9%, among whom 51.6% suffered ALBP and 48.4% suffered from CLBP. Flat feet increased the chances of having ALBP by 3.28 times and CLBP by 4.5 times. …"
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article -
1662
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
منشور في 2020"…We computed healthy life expectancy (HALE) using years lived with disability (YLDs) per capita, life tables, and standard demographic methods. …"
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1663
Crosstalk between aryl hydrocarbon receptor (AhR) and BCL-2 pathways suggests the use of AhR antagonist to maintain normal differentiation state of mammary epithelial cells during...
منشور في 2022"…ResultsActivation of the AhR/CYP1A1 pathway in mice increased EpCAMHigh/CD49fLow CD61+ luminal progenitor-like cells in early tumor formation but not in advanced tumors. …"
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article -
1664
The mechanisms of resistance of anthrax lethal toxin (LeTx)-induced cytotoxicity in AML cells. (c2018)
منشور في 2018"…Our results indicate that vertical inhibition by SCH772984 rendered the resistant cell lines sensitive to the inhibition of the MAPK-pathway and showed an increased cytotoxic effect once used in combination with anthrax lethal toxin compared to the use of anthrax lethal toxin alone.…"
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masterThesis -
1665
Association of single nucleotide polymorphisms with dyslipidemia and risk of metabolic disorders in the State of Qatar
منشور في 2023"…Finally, males were three times more likely to have dyslipidemia in comparison with females, hypertension was two times more likely to be present in the dyslipidemia group, and diabetes was six times more likely to be in the dyslipidemia group.…"
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1666
Unravelling the predictors of late cancer presentation and diagnosis in Jordan: a cross-sectional study of patients with lung and colorectal cancers
منشور في 2023"…For lung cancer, Jordanians living in rural areas were 9.29 (95% CI 2.46 to 35.1) times more likely to report late diagnosis. Jordanians who did not screen for cancer in the past were 7.02 (95% CI 1.69 to 29.18) times more likely to report late diagnosis. …"
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article -
1667
Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Bur...
منشور في 2020"…Global ambitions to accelerate progress on UHC service coverage are increasingly unlikely unless concerted action on non-communicable diseases occurs and countries can better translate health spending into improved performance. …"
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1668
WEB BASED ENGINEERING EDUCATION
منشور في 2020"…The use of Internet for distance education has received increasing attention over the past few years. But the real challenge of adapting this technology for engineering education is to facilitate the laboratory experiments via Internet. …"
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article -
1669
Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway
منشور في 2023"…Our study investigated NSP‐B's antitumor effects on MM cell lines (U266 and RPMI8226) and the involved molecular mechanisms. …"
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1670
Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy
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doctoralThesis -
1671
From past famines to present crises: The epigenetic impact of maternal malnutrition on offspring health in Gaza
منشور في 2024"…Moreover, the association between early gestational famine exposure and increased risk of psychiatric disorders like schizophrenia aligns with similar findings from the Chinese Famine of 1959–1961, reinforcing the necessity to address the psychiatric implications of prenatal environmental stressors (Susser et al., 1996, Xu et al., 2009).…"
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1672
Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
منشور في 2024"…In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). …"
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1673
Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres
منشور في 2024"…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …"
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article -
1674
Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1
منشور في 2021"…Third-dose polio vaccine (Pol3) coverage also increased, from 42·6% (41·4–44·1) in 1980 to 79·8% (78·4–81·1) in 2019, and global coverage of newer vaccines increased rapidly between 2000 and 2019. …"
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1675
Friction Reduction in Elastohydrodynamic Contacts by Thin Layer Thermal Insulation
منشور في 2014"…The results of the investigation show that the addition of thin insulating layers could lead to substantial performance increases in many applications. On a component level, the contact friction coefficient in some common machine components like gears, rolling element bearings, and cam followers can potentially be reduced by more than 40 %. …"
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article -
1676
Awareness of primary health care physicians about human papilloma virus infection and its vaccination: a cross sectional survey from multiple clinics in Saudi Arabia
منشور في 2018"…Compared to males, females were 3.1 times more likely to recommend HPV vaccines, adjusted P=0.015. …"
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article -
1677
Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
منشور في 2020"…Exposure levels for dichotomous, polytomous, and continuous risk factors were summarised with use of the summary exposure value to facilitate comparisons over time, across location, and across risks. Because the entire time series from 1990 to 2019 has been re-estimated with use of consistent data and methods, these results supersede previously published GBD estimates of attributable burden. …"
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1678
Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1
منشور في 2015"…PrAgU2/LF was cytotoxic to five out of nine AML cell lines. Cytotoxicity of PrAgU2/LF appeared to be nonapoptotic and was associated with MAPK activation and urokinase activity because all the PrAgU2/LF-sensitive cell lines showed both uPAR expression and high levels of MEK1/2 phosphorylation. …"
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article -
1679
Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia
منشور في 2019"…Curcumin induces apoptosis in B-Pre-ALL cell lines via activation of caspase-8 and truncation of BID. …"
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1680
Precision meets repurposing: Innovative approaches in human papillomavirus and Epstein-Barr virus-driven cancer therapy
منشور في 2024"…HPV and EBV are known to be increasingly involved in the pathogenesis of various classes of cancers like cervical, head and neck, colorectal, breast, oral and anogenitial. …"
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article