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261
Impact of abiraterone on patient-related outcomes in metastatic castration-resistant prostate cancer
منشور في 2017"…Abiraterone acetate has established a major role in the treatment paradigm of metastatic castration-resistant prostate cancer ever since pivotal trials, COU-AA-301 and COU-AA-302, have shown benefit in both the second-line and first-line (post- and pre-chemotherapy) setting, respectively, with improvement in overall survival as well as secondary end points such as prostate-specific antigen (PSA) and radiographic response rates, time to PSA progression, and progression-free survival. …"
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article -
262
Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021
منشور في 2024"…The mortality rate of URIs in 2021 was 0·2 per 100 000 (0·1 to 0·5), a decrease of 64·2% (–84·6 to –43·4) from 1990, when the mortality rate was 0·7 per 100 000 (0·2 to 1·1). …"
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article -
263
Targeting deregulated oxidative stress in skin inflammatory diseases: An update on clinical importance
منشور في 2022"…However, research obtained over the last few decades has revolutionized the understanding of cutaneous disease pathogenesis and therapeutic developments. In this line, increasing data from pre-clinical and clinical studies implicates the crucial role of oxidative stress in pathogenesis and complications of cutaneous inflammatory diseases, including atopic dermatitis and psoriasis. …"
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264
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"
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265
An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im...
منشور في 2020"…Zayed University-Dubai had greater STEM majors’ enrolments compared to Zayed University-Abu Dhabi. …"
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266
Catalytic Transformation Of C-7-C9 Methyl Benzenes Over USY-Based FCC Zeolite Catalyst
منشور في 2020"…The sequence of reactivity of the three alkyl benzenes was found to decrease as the number of methyl group per benzene ring decreases, as follows: 1,2,4-trimethylbenzene > m-xylene > toluene. …"
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article -
267
Solar water heating in Lebanon
منشور في 2006"…Simplified initial estimates indicate a payback period of 4–5 years while advanced mathematical models (RETScreen) indicate that the most advanced evacuated tube technology has a payback period of less than 9 years at current market prices. With decreasing cost per square meter of installed collectors, payback periods are expected to rapidly decrease. …"
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article -
268
The effects of a change in the point system on immigration
منشور في 2016"…The explicit objective was to increase the number of French-speaking immigrants, with no deterioration in overall labor market performance. …"
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article -
269
Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
منشور في 2020"…Deaths due to chronic respiratory diseases numbered 3 914 196 (95% UI 3 790 578–4 044 819) in 2017, an increase of 18·0% since 1990, while total DALYs increased by 13·3%. …"
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270
Trade Flow and Nation Brand Distance: A Structural Gravity Model Approach
منشور في 2021"…The results on the impact of NBD on FTA and trade flows provides some interesting insights as the there is a negative and significant moderation impact of NBD on the relationship between FTA and both export and import volume which suggest that a decrease of NBD will increase the effect of FTA on trade flow. …"
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271
Ultrasound‑triggered herceptin liposomes for breast cancer therapy
منشور في 2021"…Exposing the liposomes to low-frequency ultrasound (LFUS) triggered drug release which increased with the increase in power density. Trastuzumab conjugation resulted in enhancing the sensitivity of the liposomes to LFUS. …"
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article -
272
Type 2 Diabetes Mellitus Automated Risk Detection Based on UAE National Health Survey Data: A Framework for the Construction and Optimization of Binary Classification Machine Learn...
منشور في 2020"…ML based informal diagnostic and decision support systems can provide a first line of detection to alert patients about potential disease risk. …"
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273
Successful Use of Intravenous B-blocker Therapy in Cardiogenic Shock Supported With Venoarterial Extracorporeal Membrane Oxygenation: A Case Series
منشور في 2022"…<p dir="ltr">Tachycardia in cardiogenic shock (CS) might reduce the cardiac output (CO) by decreasing the ventricular filling time. Nevertheless, heart rate (HR) control with agents that possess negative inotropy might decrease the CO. …"
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274
An atomistic molecular dynamic model to study the properties of LLDPE and wax
منشور في 2023"…After validation, the application of the model showed that the branch content of modelled LLDPE affected the glass transition temperature when the branch content was 70 per 1000 carbons for models with different branch lengths. …"
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275
Solar hydrogen production via thermochemical magnesium oxide – Magnesium sulfate water splitting cycle
منشور في 2020"…As per the analysis, this cycle achieved the highest solar-to-fuel energy conversion efficiency (47.7%) at the molar flow rate of Ar = 1 mol/s, thermal reduction temperature = 1490 K, and water splitting temperature = 475 K. …"
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276
Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE
منشور في 2018"…Furthermore, building orientation plays a significant role in the thermal performance of the urban block, and it contributes to the total cooling load energy saving of the urban block by 6.6 % at the peak time of cooling demand. Moreover, the research found that the variation in building heights will increase the wind velocity by up to 23 %, and this improvement in air flow affects the outdoor air temperature positively. …"
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277
Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro
منشور في 2017"…To confirm apoptosis, AnnexinV/PI dual staining method was performed showing a time- and dose-dependent increase in the number of cells in the early and late apoptosis stage. …"
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article -
278
Exploring Effects of Mental Stress with Data Augmentation and Classification Using fNIRS
منشور في 2025"…Notably, after augmenting the data with DCGAN, the classification accuracy increases dramatically to 96%. In the time series data, statistically significant differences were noticed in the data before and after BB stimulation, which showed an improvement in the brain state, in line with the classification results. …"
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279
The history and development of newspaper electronic pagination systems in the United States, 1975-1987
منشور في 1990"…Chapter II reviews the history of printing from ancient times, to Gutenberg's invention of movable type, through Mergenthaler's line-casting machine, to the invention of cold type processes in the 1940s. …"
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masterThesis -
280
Chemical, rheological, and sensory properties of wheat biscuits fortified with local buckwheat
منشور في 2023"…The additional increment enhanced the arrival time, dough development time, dough stability, the mixing tolerance index, and weakening. …"