Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells In Vitro حسب El Khoury, Marianne

"…Treatment of AML cell lines with M. pseudolavatera methanolic leaf extract showed a dose- and time-dependent inhibition of proliferation and a dose-dependent increase in apoptotic hallmarks such as an increase in phosphatidylserine on the outer membrane leaflet and membrane leakage in addition to DNA fragmentation. …"
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The antioxidant and anticancer effects of Wild Carrot oil extract حسب Shebaby, Wassim Nasri

"…The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …"
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An adaptive load-balancing approach to XML-based network management using JPVM حسب Sqalli, M.H.

"…In this paper, we propose a framework for adaptive load-balancing using JPVM for XML-based network management. The goal is to increase the efficiency of processing the management data, and decrease the communication time by distributing the management load across multiple XML/SNMP gateways. …"
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A Comprehensive Method of Ion Exchange Resins Regeneration and Its Optimization for Water Treatment حسب Al-Asheh, Sameer

"…Water conductivity, as an indicator of regeneration efficiency, was monitored over time at the different conditions and scenario. In general, it was observed that the conductivity decreases with time until one point is reached and then starts to increase as a result of resin saturation. …"
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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications حسب Pramod Darvin (153341)

"…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"

Characterization of the Potency and Mechanism of Action of a Novel Dual-Selective Intermolecularly Complemented Version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Breas... حسب Basala, Sobhiya

"…In this study, we demonstrated for first time the potency of the novel, intermolecularly complemented version of anthrax toxin, IMC/FP59 on breast cancer cell lines, its mode of action and mechanism of cell death.…"
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A comprehensive design and rating study of evaporative coolers and condensers. Part I. Performance evaluation حسب QURESHI, BILAL AHMED

"…Furthermore, it is noted that there is about 4.7% increase in outlet process fluid temperature of the evaporative fluid cooler. …"
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Targeting potential arginine auxotrophy in glioblastoma (GBM) cells using human recombinant arginase I (CO)-PEG 5000 [HuArgl (Co)-PEG5000]. (c2013) حسب Khoury, Oula

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Brain Connectivity Analysis Under Semantic Vigilance and Enhanced Mental States حسب Yahya, Fares

"…The audio stimulation enhances the connectivity network over the frontal and parietal regions and the right hemisphere. The increase in the connectivity network correlates with individual differences in the magnitude of the vigilance enhancement assessed by response time to stimuli. …"
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A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia... حسب Abi-Habib, Ralph J.

"…The activity of this toxin was then tested on a larger group of 13 human AML cell lines; 5 of the 13 cell lines were sensitive to DTU2GMCSF. …"
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The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013) حسب Khoury, Nathalie El

"…Western blot assay results confirmed the previously observed increase in apoptosis as it showed an increase in Bax:Bcl-2 expression upon kefir treatment. …"
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Comparative Effect of Sodium Butyrate and Sodium Propionate on Ovarian Cancer Migration, Invasion, and Epithelial-To-Mesenchymal Transition حسب Sleem, Reem

"…Methodology: The two ovarian cancer cell lines, SKOV-3 and PA-1, were treated with NaB and NaP for 24h. …"
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Postprandial lipaemia 10 and 34 hours after playing football: Does playing frequency affect the response? حسب Darren J. Paul (6905450)

"…<p dir="ltr">Elevated postprandial triglyceride (TG) is associated with increased risk of cardiovascular disease. The time window for the last bout beneficial effect on postprandial lipaemia after football play is unknown. …"

Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute... حسب Farhat, Mirna

"…Finally, while IMC/LF treatment did not affect the expression of any of the proteases tested (uPAR, MMP2, and MMP9), treatment with IMC/FP59 did affect their expression with significant cytotoxic responses seen only in cells whose uPAR expression was not affected at any time point post-treatment. In this study, we showed for the first time the potency of IMC PrAg variant on AML cell lines, its mode of action, as well as its mechanism of cell death.…"
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Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) حسب El Jawhari, Yassmine

"…The addition of chloroquine, an autophagy inhibitor, increased the sensitivity of cells to [HuArgI (Co)-PEG5000]-mediated arginine depletion at earlier time points. …"
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Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes حسب Rizk, Sandra

"…The percent reduction in proliferation was very significant, and was dose-, and time-dependent. In both cell lines, kefir exhibited its antiproliferative effect by downregulating TGF-α and upregulating TGF-β1 mRNA expression. …"
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Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) حسب Azar, Daniel Fadi

"…Furthermore, we have attempted to examine the photochemical potential of our metal-organic compound model by combining L-II and L-III in the same metal complex, thus generating four final complexes with differing net charges (from +2 to -4), and examining their activities on a panel of AML cell lines with or without exposure to blue light. Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …"
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The Anti-Tumor Effect of Flaxseed Lignan Derivatives on Different Acute Myeloid Leukemia Cancer Cells حسب Tannous, Stephanie

"…Cytotoxicity assays, using WST-1, revealed dose- and time- dependent effects in various AML cell lines with the most prominent cytotoxicity exhibited by ENL. …"
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Targeting human acute myeloid leukemia cells using human recombinant arginase I (Co) - PEG5000 [HuArgl (Co) - PEG5000] - induced arginine depletion. (c2013) حسب Tanios, Rita Farid

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Anti-cancer Evaluation of Lebanese Cannabis Oil Extract on Lung and Breast Cancer Cells حسب Saliba, Jane

"…In this study, we look at the anti-tumorigenic effects of Lebanese COE on non-small cell lung cancer cell line (NSCLC) A549 and the triple negative breast cancer cell line (MDA-MB-231). …"
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