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481
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"
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482
Fire detection and anti-fire system to enhance food security: A concept of smart agriculture systems-based IoT and embedded systems with machine-to-machine protocol
منشور في 2025"…This is due to: 1) the growth of the world population, 2) the decline of natural resources, 3) the loss of agricultural land, and 4) the increase of unforeseen environmental conditions (storms, fires, and other natural hazards). …"
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article -
483
Corrosion Monitoring Technologies for Reinforced Concrete Structures: A Review
منشور في 2023"…Due to the vital impact size of corrosion of RC structures in the form of high maintenance demand and an increase in the total life cycle cost, corrosion monitoring, early detection, and timely remediation is considered a necessity and a crucial proactive measure to control corrosion and limit its impact. …"
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484
Types of PMO and their roles in the UAE Oil & Gas Production Companies
منشور في 2014"…Some researchers argued that this failure might be due to the increase in the concurrent projects number in big organizations which were increasing the project management complexity while competing, and in the same time depleting the organization resources. …"
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485
Spatiotemporal mapping of groundwater salinity in Al-Batinah, Oman
منشور في 2021"…A salinity map was created to track the changes in groundwater salinity over time in the study area. The results show that water salinity increases over time due to the increase in urbanization and over-pumping of water from these wells. …"
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article -
486
Cooling Energy and Climate Change Nexus in Arid Climate and the Role of Energy Transition
منشور في 2023"…Climate change is expected to increase cooling demand, further exacerbating the problem. …"
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487
Flexural strengthening of reinforced concrete beams with CFRP laminates and spike anchors
منشور في 2024"…This is primarily due to the increase in the fan length and thickness as the anchor's dowel diameter increases.…"
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article -
488
Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres
منشور في 2024"…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …"
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article -
489
Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes
منشور في 2025"…The financial value of PALYs was determined based on the gross domestic product (GDP) per full-time worker (i.e. US$80,573). The base-case model estimated the productivity burden of CVD, and interventional scenarios were simulated to assess potential gains resulting from improved control of modifiable risk factors, including reduced incidence of T2D, lower systolic blood pressure (SBP), decreased number of smokers, and reduced total cholesterol. …"
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490
YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm
منشور في 2025"…Compared to the standard YOLOv11 model, the proposed YOLO-DefXpert attained an improvement of 9.3% and 13.2% in mAP50 and mAP95, an 11.25% increase in frames per second, and a 69.85MB decrease in model size. …"
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491
Regulative Loop between β-catenin and Protein Tyrosine Receptor Type γ in Chronic Myeloid Leukemia
منشور في 2020"…Furthermore, we demonstrated that the increased expression of β-catenin in PTPRG-negative CML cell lines correlates with DNA (cytosine-5)-methyl transferase 1 (DNMT1) over-expression, which is responsible for PTPRG promoter hypermethylation, while its inhibition or down-regulation correlates with PTPRG re-expression. …"
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492
The Impact of an Ethnomathematics Intervention on Sixth Graders’ Perceptions about the Nature of Mathematics
منشور في 2023"…The focus of the study was on students’ perceptions about the nature of mathematics in terms of its connectedness to culture and real life in addition to the role of mathematics education in promoting social and political values. …"
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masterThesis -
493
Road safety and traffic medicine in Iran: Achievements and challenges
منشور في 2015"…<p dir="ltr">Road traffic injuries found to be the second rank of Years of Life Lost (YLL) and third rank of Disability Adjusted Life Years (DALY) in Iran based on Global Burden of Disease 2010. …"
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494
A Feasibility Study for Solar Energy Generation Policy Mechanisms in The UAE
منشور في 2021احصل على النص الكامل
doctoralThesis -
495
Effects of COVID-19 on Autism Spectrum Disorder in Qatar
منشور في 2024"…<h3>Introduction</h3><p dir="ltr">The unprecedented impact of the coronavirus pandemic (COVID-19) has had profound implications on the ASD community, including disrupting daily life, increasing stress and emotional dysregulation in autistic children, and worsening individual and family well-being.…"
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496
Spatiotemporal mapping of groundwater salinity in Al-Batinah, Oman
منشور في 2021"…A salinity map was created to track the changes in groundwater salinity over time in the study area. The results show that water salinity increases over time due to the increase in urbanization and over-pumping of water from these wells. …"
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497
What drives cryptocurrency pump and dump schemes: Coin versus market factors?
منشور في 2024"…Furthermore, the study employs count time-series models to examine market-based factors. …"
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498
Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
منشور في 2024"…In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). …"
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499
The present and future disease burden of hepatitis C virus infections with today's treatment paradigm – volume 3
منشور في 2015"…The total number, morbidity and mortality attributed to viraemic hepatitis C virus (HCV) infections change over time making it difficult to compare reported estimates from different years. …"
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article -
500
A Fast and Robust Gas Recognition Algorithm Based on Hybrid Convolutional and Recurrent Neural Network
منشور في 2019"…In addition, the aforesaid accuracy can be further improved by increasing the response time with the step of 0.5 s. …"