Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells By Peter Nasr A thesis حسب Nasr, Peter

"…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Water Footprint Assessment and Virtual Water Trade in the Globally Most Water-Stressed Country, Qatar حسب Nayla Higazy (17679453)

"…<p dir="ltr">Qatar is one of the most water stressed countries globally, despite Qatar’s aridity and its lack of freshwater resources, per capita water consumption became one of the highest in the world due to population growth, agricultural expansion, rapid urbanization and industrialization and it is expected to increase in the coming decades. …"

Visitors off the trail: Impacts on the dominant plant, bryophyte and lichen species in alpine heath vegetation in sub-arctic Sweden حسب Monika, Rawat

"…With a greater decrease in taller forbs and shrubs than in graminoids and prostrate plants, a greater decrease in lichen than in bryophyte species, and a change in vegetation composition. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Strategie trading company (STC). (c1994) حسب Rbeiz, Marc

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells In Vitro حسب El Khoury, Marianne

"…Treatment of AML cell lines with M. pseudolavatera methanolic leaf extract showed a dose- and time-dependent inhibition of proliferation and a dose-dependent increase in apoptotic hallmarks such as an increase in phosphatidylserine on the outer membrane leaflet and membrane leakage in addition to DNA fragmentation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The antioxidant and anticancer effects of Wild Carrot oil extract حسب Shebaby, Wassim Nasri

"…The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

A Comprehensive Method of Ion Exchange Resins Regeneration and Its Optimization for Water Treatment حسب Al-Asheh, Sameer

"…Water conductivity, as an indicator of regeneration efficiency, was monitored over time at the different conditions and scenario. In general, it was observed that the conductivity decreases with time until one point is reached and then starts to increase as a result of resin saturation. …"
احصل على النص الكامل

Cost-effectiveness of novel treatment of hepatitis C virus in Lebanese patients حسب Nasser, Soumana C.

"…Sensitivity analysis showed that a 25% decrease in the cost of dual drug option resulted in a decrease of incremental cost to 16,982 euro per QALY gained at first year of treatment with DAAs upon early HCV diagnosis. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications حسب Pramod Darvin (153341)

"…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"

Characterization of the Potency and Mechanism of Action of a Novel Dual-Selective Intermolecularly Complemented Version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Breas... حسب Basala, Sobhiya

"…In this study, we demonstrated for first time the potency of the novel, intermolecularly complemented version of anthrax toxin, IMC/FP59 on breast cancer cell lines, its mode of action and mechanism of cell death.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Targeting potential arginine auxotrophy in glioblastoma (GBM) cells using human recombinant arginase I (CO)-PEG 5000 [HuArgl (Co)-PEG5000]. (c2013) حسب Khoury, Oula

احصل على النص الكامل
احصل على النص الكامل

Growth hormone treatment modulates active ghrelin levels in rats حسب Haddad, Haytham

"…Consequently, under such treatment, determination of active ghrelin concentration per tissue mass rather than per tissue protein is favored. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Performance assessment of an integrated absorption cooling-hydrogen liquefaction system using geothermal energy حسب Gadalla, Mohamed

"…The results show that the mass of hydrogen gas pre-cooled by the absorption system per unit mass flow rate of geothermal water flowing through the system (n) and the amount of hydrogen liquefied per unit mass flow rate of geothermal water flowing through the system (y) increase with an increase in the geothermal source temperature. …"
احصل على النص الكامل

A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia... حسب Abi-Habib, Ralph J.

"…The activity of this toxin was then tested on a larger group of 13 human AML cell lines; 5 of the 13 cell lines were sensitive to DTU2GMCSF. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013) حسب Khoury, Nathalie El

"…Western blot assay results confirmed the previously observed increase in apoptosis as it showed an increase in Bax:Bcl-2 expression upon kefir treatment. …"
احصل على النص الكامل
احصل على النص الكامل

Comparative Effect of Sodium Butyrate and Sodium Propionate on Ovarian Cancer Migration, Invasion, and Epithelial-To-Mesenchymal Transition حسب Sleem, Reem

"…Methodology: The two ovarian cancer cell lines, SKOV-3 and PA-1, were treated with NaB and NaP for 24h. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Postprandial lipaemia 10 and 34 hours after playing football: Does playing frequency affect the response? حسب Darren J. Paul (6905450)

"…<p dir="ltr">Elevated postprandial triglyceride (TG) is associated with increased risk of cardiovascular disease. The time window for the last bout beneficial effect on postprandial lipaemia after football play is unknown. …"

Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute... حسب Farhat, Mirna

"…Finally, while IMC/LF treatment did not affect the expression of any of the proteases tested (uPAR, MMP2, and MMP9), treatment with IMC/FP59 did affect their expression with significant cytotoxic responses seen only in cells whose uPAR expression was not affected at any time point post-treatment. In this study, we showed for the first time the potency of IMC PrAg variant on AML cell lines, its mode of action, as well as its mechanism of cell death.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) حسب El Jawhari, Yassmine

"…The addition of chloroquine, an autophagy inhibitor, increased the sensitivity of cells to [HuArgI (Co)-PEG5000]-mediated arginine depletion at earlier time points. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

An improved non-dimensional model of wet-cooling towers حسب QURESHI, BILAL AHMED

"…The first method shows a maximum decrease of 4.4 per cent in error, whereas in the second method, the maximum error was found to be 3.3 and 6.8 per cent when the inlet air was unsaturated and saturated, respectively. …"
احصل على النص الكامل