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Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells
Published 2022“…<p>Neosetophomone B (NSP–B), a meroterpenoid fungal secondary metabolite, was investigated for its anticancer potential in leukemic cell lines (K562 and U937). NSP-B treatment of leukemic cells suppressed cell viability by triggering apoptotic cell death. …”
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262
Scalable Generation of Mesenchymal Stem Cells and Adipocytes from Human Pluripotent Stem Cells
Published 2020“…Disruption of cell adhesion induced the subsequent differentiation of the highly expanded RA-derived EB-forming cells into a pure population of multipotent MSCs (up to 1542-fold increase in comparison to RA-untreated counterparts). …”
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263
Investigating the Fluorescence Quenching of Doxorubicin in Folic Acid Solutions and Its Relation to Ligand-Targeted Nanocarriers
Published 2015“…The folate receptor is widely expressed on the surface of several cell lines and tumors; including ovarian, brain, kidney, breast, and lung cancers. …”
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264
Evaluation of pretreatment and membrane configuration for pressure-retarded osmosis application to produced water from the petroleum industry
Published 2021“…PRO is typically considered with seawater/river water pairings however greater energy can be recovered from hypersaline solutions including produced water (PW) from the petroleum industry. …”
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Graphite and metal nitrate-infused HDPE composites for enhanced thermal performance in energy-efficient building envelopes
Published 2025“…Analysis such as Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA), Scanning Electron Microscopy (SEM), and dielectric spectroscopy analyses further revealed extensive interaction between filler matrices, a decrease in phonon scattering, and a positive increase in crystallinity which led to the improved thermal performance.The TGA results showed that the composite exhibited greater thermal stability, and the residue mass after the decomposition process was 9%, indicating increased carbonization and structural integrity. …”
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266
Western diet induces mild metabolic impairment and aggravates neuropathology in an experimental mouse model of traumatic brain injury
Published 2024“…Individuals with TBI have a greater risk of mortality from associated chronic diseases than the general population. …”
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267
A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia...
Published 2004“…The activity of this toxin was then tested on a larger group of 13 human AML cell lines; 5 of the 13 cell lines were sensitive to DTU2GMCSF. …”
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PSA-activated proaerolysin as a prostate specific cancer therapy
Published 2006“…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …”
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271
Phase transitions of nanoemulsions using ultrasound: Experimental observations
Published 2012“…Additionally, as the size of the emulsion droplet increased, the intensity required for bubble formation decreased. As expected, perfluorohexane emulsions require greater intensity to form cavitating bubbles than perfluoropentane emulsions.…”
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272
Spatial and temporal assessment of metal pollution in the sediments of the Qaraoun reservoir, Lebanon
Published 2016“…Total metal concentrations and the environmental indices indicated increased pollution with time. Total organic carbon data showed a remarkable and significant increase in the organic fraction in 2013 relative to previous years. …”
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273
Electrochemical response in ionic polymer transducers
Published 2008“…The charge density accumulated at the electrode also increases with the dielectric permittivity. An increase of the diffusion coefficient increases the peak current and results in a smaller time decay constant. …”
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Snake venom in conjugation with silica nanoparticles: an emerging cancer therapy
Published 2025“…<i>In vitro</i> investigations on cancer cell lines revealed a considerable increase in cytotoxicity and induction of apoptosis as compared to free snake venom, with greater selectivity for malignant cells. …”
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277
Burst Round Robin as a Proportional-Share Scheduling Algorithm
Published 2020“…This will reduce the number of processes in the ready queue by knocking out short jobs relatively faster in a hope to increase the throughput and reduce the average waiting time.…”
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278
Indirect tool-wear maps for tool condition monitoring in dry metal drilling operations
Published 2011“…For verification, this index is found to positively track the corresponding increase in cutting forces. Utilizing this index, an implementation example is presented in this paper by which a real-time tool monitoring of chisel drills is achieved by inputting the CRI along with the cutting parameters to an Artificial Neural Network (ANN) which yielded good tool condition predictions.…”
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Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia
Published 2019“…Curcumin induces apoptosis in B-Pre-ALL cell lines via activation of caspase-8 and truncation of BID. …”