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301
Impact of abiraterone on patient-related outcomes in metastatic castration-resistant prostate cancer
منشور في 2017"…Abiraterone acetate has established a major role in the treatment paradigm of metastatic castration-resistant prostate cancer ever since pivotal trials, COU-AA-301 and COU-AA-302, have shown benefit in both the second-line and first-line (post- and pre-chemotherapy) setting, respectively, with improvement in overall survival as well as secondary end points such as prostate-specific antigen (PSA) and radiographic response rates, time to PSA progression, and progression-free survival. …"
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302
Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021
منشور في 2024"…The mortality rate of URIs in 2021 was 0·2 per 100 000 (0·1 to 0·5), a decrease of 64·2% (–84·6 to –43·4) from 1990, when the mortality rate was 0·7 per 100 000 (0·2 to 1·1). …"
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303
Targeting deregulated oxidative stress in skin inflammatory diseases: An update on clinical importance
منشور في 2022"…However, research obtained over the last few decades has revolutionized the understanding of cutaneous disease pathogenesis and therapeutic developments. In this line, increasing data from pre-clinical and clinical studies implicates the crucial role of oxidative stress in pathogenesis and complications of cutaneous inflammatory diseases, including atopic dermatitis and psoriasis. …"
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304
Evaluation of waterpipe smoke toxicity in C57BL/6 mice model
منشور في 2020"…Additionally, severe significant DNA damages (p < 0.05) were reported in the lungs, kidneys, bone marrow and liver of waterpipe-exposed animals, using MTS and COMET assays. …"
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305
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306
Catalytic Transformation Of C-7-C9 Methyl Benzenes Over USY-Based FCC Zeolite Catalyst
منشور في 2020"…The sequence of reactivity of the three alkyl benzenes was found to decrease as the number of methyl group per benzene ring decreases, as follows: 1,2,4-trimethylbenzene > m-xylene > toluene. …"
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307
Solar water heating in Lebanon
منشور في 2006"…Simplified initial estimates indicate a payback period of 4–5 years while advanced mathematical models (RETScreen) indicate that the most advanced evacuated tube technology has a payback period of less than 9 years at current market prices. With decreasing cost per square meter of installed collectors, payback periods are expected to rapidly decrease. …"
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308
Portal Vein Embolization in Hilar Cholangiocarcinoma
منشور في 2009"…In patients whose standardized future liver remnant is less than or equal to 20% of total liver volume, portal vein embolization (PVE) should be performed. …"
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309
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310
The effects of a change in the point system on immigration
منشور في 2016"…The explicit objective was to increase the number of French-speaking immigrants, with no deterioration in overall labor market performance. …"
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311
Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
منشور في 2020"…Deaths due to chronic respiratory diseases numbered 3 914 196 (95% UI 3 790 578–4 044 819) in 2017, an increase of 18·0% since 1990, while total DALYs increased by 13·3%. …"
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312
Risk of venous thromboembolism outweighs post-hepatectomy bleeding complications
منشور في 2012"…Conclusions: Contrary to the belief that transient postoperative liver insufficiency is protective, VTE increases with extent of hepatectomy. …"
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313
Ultrasound‑triggered herceptin liposomes for breast cancer therapy
منشور في 2021"…Exposing the liposomes to low-frequency ultrasound (LFUS) triggered drug release which increased with the increase in power density. Trastuzumab conjugation resulted in enhancing the sensitivity of the liposomes to LFUS. …"
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314
Type 2 Diabetes Mellitus Automated Risk Detection Based on UAE National Health Survey Data: A Framework for the Construction and Optimization of Binary Classification Machine Learn...
منشور في 2020"…ML based informal diagnostic and decision support systems can provide a first line of detection to alert patients about potential disease risk. …"
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315
Successful Use of Intravenous B-blocker Therapy in Cardiogenic Shock Supported With Venoarterial Extracorporeal Membrane Oxygenation: A Case Series
منشور في 2022"…<p dir="ltr">Tachycardia in cardiogenic shock (CS) might reduce the cardiac output (CO) by decreasing the ventricular filling time. Nevertheless, heart rate (HR) control with agents that possess negative inotropy might decrease the CO. …"
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316
An atomistic molecular dynamic model to study the properties of LLDPE and wax
منشور في 2023"…After validation, the application of the model showed that the branch content of modelled LLDPE affected the glass transition temperature when the branch content was 70 per 1000 carbons for models with different branch lengths. …"
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317
Solar hydrogen production via thermochemical magnesium oxide – Magnesium sulfate water splitting cycle
منشور في 2020"…As per the analysis, this cycle achieved the highest solar-to-fuel energy conversion efficiency (47.7%) at the molar flow rate of Ar = 1 mol/s, thermal reduction temperature = 1490 K, and water splitting temperature = 475 K. …"
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318
Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE
منشور في 2018"…Furthermore, building orientation plays a significant role in the thermal performance of the urban block, and it contributes to the total cooling load energy saving of the urban block by 6.6 % at the peak time of cooling demand. Moreover, the research found that the variation in building heights will increase the wind velocity by up to 23 %, and this improvement in air flow affects the outdoor air temperature positively. …"
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319
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"
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320
Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro
منشور في 2017"…To confirm apoptosis, AnnexinV/PI dual staining method was performed showing a time- and dose-dependent increase in the number of cells in the early and late apoptosis stage. …"
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