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2841
Human AGR2 Deficiency Causes Mucus Barrier Dysfunction and Infantile Inflammatory Bowel Disease
منشور في 2021"…Patient biopsy specimens showed reduced goblet cells; depletion of MUC2, MUC5AC, and MUC6; up-regulation of AGR2; and increased ER stress. …"
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2842
Chamber investigation of the formation and transformation of secondary organic aerosol in mixtures of biogenic and anthropogenic volatile organic compounds
منشور في 2022"…The α-pinene–o-cresol system yield appeared to be increased compared to that calculated based on the additivity, whilst in the α-pinene–o-cresol–isoprene system the measured and predicted yields were comparable. …"
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2843
Salivary α-amylase activity is associated with cardiometabolic and inflammatory biomarkers in overweight/obese, non-diabetic Qatari women
منشور في 2024"…<h3>Introduction</h3><p dir="ltr">Obesity, prevalent in approximately 80% of Qatar’s adult population, increases the risk of complications like type 2 diabetes and cardiovascular diseases. …"
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2844
Epigenetic DNA Methylation Signatures Associated With the Severity of Paget’s Disease of Bone
منشور في 2022"…<h3>Background: </h3><p dir="ltr">Paget’s disease of bone (PDB) is characterized by focal areas of dysregulated bone turnover resulting in increased bone loss and abnormal bone formation with variable severity. …"
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2845
Overview of Artificial Intelligence–Driven Wearable Devices for Diabetes: Scoping Review
منشور في 2022"…<h3>Background</h3><p dir="ltr">Prevalence of diabetes has steadily increased over the last few decades with 1.5 million deaths reported in 2012 alone. …"
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2846
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2847
A systematic review and meta-analysis on the impact of early vs. delayed pharmacological thromboprophylaxis in patients with traumatic brain injury
منشور في 2024"…Early PTP was categorized based on the timing of administration: 1) within 24 h, 2) within 48 h, and 3) within 72 h of hospital admission. …"
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2848
The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc...
منشور في 2019"…In pro-inflammatory states such as PCOS, spontaneous activation of the alternative pathway of complement results in increased generation of acylation stimulating protein (ASP) from adipocytes irrespective of body mass index.…"
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2849
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2850
HIV incidence among people who inject drugs in the Middle East and North Africa: mathematical modelling analysis
منشور في 2018"…In addition, 20 to 2208 and 5 to 837 new annual infections were estimated across the different countries among sexual partners of PWID and ex‐PWID respectively. …"
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2851
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2852
Adipocyte Enhancer-Binding Protein 1 (AEBP1) (a Novel Macrophage Proinflammatory Mediator) Overexpression Promotes and Ablation Attenuates Atherosclerosis in ApoE⁻′⁻ and LDLR⁻′⁻ Mi...
منشور في 2011"…Macrophages from ApoE⁻′⁻/TG-BM chimeric mice express reduced levels of PPARγ₁, LXRα, ATP-binding cassette A₁ (ABCA₁) and ATP-binding cassette G₁ (ABCG₁) and increased levels of the inflammatory mediators interleukin (IL)-6 and tumor necrosis factor (TNF)-α compared with macrophages of control chimeric mice (ApoE⁻′⁻/NT-BM) that received AEBP₁ nontransgenic (AEBP₁ᴺᵀ) BM cells. …"
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2853
Helios Should Not Be Cited as a Marker of Human Thymus-Derived Tregs. Commentary: Helios+ and Helios− Cells Coexist within the Natural FOXP3+ T Regulatory Cell Subset in Humans
منشور في 2016"…Shevach’s group reported that Helios expression discriminates tTregs from pTregs (5). This work generated a lot of excitement due to the real need for markers to discriminate the good tTregs from the bad pTregs. …"
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2854
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2855
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2856
What’s So Great About Home?
منشور في 2008"…And I prefer not to label myself because I feel when writing about women that I am writing by extension to all human beings.”5 Notwithstanding the above, I propose in this essay to give La maison sans racines and Hikāyat Zahra the general description of a literature of displacement. …"
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2857
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration
منشور في 2018"…</p><h3>Conclusions</h3><p dir="ltr">Our results demonstrate that increases in microglia displaying a reactive morphology and MHC-II expression occur in the substantia nigra in close association with peak numbers of pSyn inclusions, months prior to nigral dopamine neuron degeneration, and suggest that reactive microglia may contribute to vulnerability of SNc neurons to degeneration. …"