Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro by Rizk, Sandra

“…The pro-apoptotic effect upon combination of topotecan with andrographolide was further observed using annexin V/PI staining; even though andrographolide alone did not alter cell survival, however, when applied to the cells prior to topotecan treatment, the number of apoptotic cells increased from 16% to 57%. Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…”
Get full text
Get full text
Get full text

ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] by Abdel Khalek, Maya

“…Secondly, the results also showed in both U251 and A172 cells, an increase in the percentage of the survival of cells co-treated with HuArgI (Co)-PEG5000 and chloroquine; indicating that autophagy is contributing to cell death at late time points in GBM cells. …”
Get full text
Get full text
Get full text

Targeting human acute myeloid leukemia cells using human recombinant arginase I (Co) - PEG5000 [HuArgl (Co) - PEG5000] - induced arginine depletion. (c2013) by Tanios, Rita Farid

Get full text
Get full text

Minimization of the amplitude of the entire span of beams using mass dampers by Issa, Jimmy S.

“…Since minimizing the amplitude at one point of the beam might increase it at another point, in this work the maximum amplitude along the entire beam span is minimized. …”
Get full text
Get full text
Get full text
Get full text

Do high energy-efficient buildings increase overheating risk in cold climates? Causes and mitigation measures required under recent and future climates by Mutasim Baba, Fuad

“…While without adequate ventilation, the overheating risk in high-energy-efficient buildings can be higher than old buildings, where decreasing wall and window U-values and infiltration rate has a greater contribution to the increase of indoor temperature, while decreasing window SHGC has a lower contribution to the decrease in indoor temperature compared to the case with adequate ventilation. …”
Get full text
Get full text
Get full text

Cytotoxicity of Anthrax Lethal Toxin to Human Acute Myeloid Leukemia Cells Is Nonapoptotic and Dependent on Extracellular Signal-Regulated Kinase 1/2 Activity by Abi-Habib, Ralph J.

“…We tested potency of LeTx on a panel of 11 human AML cell lines. Seven cell lines showed cytotoxic responses to LeTx. …”
Get full text
Get full text
Get full text

Renewable Energy Consumption and Carbon Emissions: Evidence from an Oil-Rich Economy by Shahriyar Mukhtarov (19325662)

“…The results reveal that renewable energy consumption has a negative impact on CO₂ emissions, while real GDP per capita has a positive effect. According to the findings, a 1% increase in renewable energy consumption leads to a 0.26% decrease in consumption-based CO₂ emissions, while a 1% rise in real GDP per capita leads to a 0.46% rise in consumption-based CO₂ emissions. …”

Targeting solid tumor cells with novel photosensitive ruthenium-based metal-organic compounds. (c2016) by Farhat, Stephanie Roy

“…As for the free ligands, L-II presented major cytotoxic effect on five out of six cell lines, L-I on two cell lines, L-IV on one cell line only. …”
Get full text
Get full text
Get full text

The protective role of lidocaine in surgeries involving trigeminal nerve manipulation: a meta-analysis of trigeminocardiac reflex prevention by Almonzer Al-Qiami (22393303)

“…This leads to a rapid increase in parasympathetic activity, resulting in a decrease in heart rate (HR) and blood pressure, which can potentially lead to bradycardia, and cardiac arrest, with a prevalence of 14.5% during neurointerventional procedures (8). …”

Gaining or Losing Team Ball Possession: The Dynamics of Momentum Perception and Strategic Choice in Football Coaches by Walid Briki (688845)

“…Nonetheless, both variables displayed asymmetrical effects, in the sense that: (1) the strength of positive PM appeared to be easier to decrease than to increase; and (2) the greater the positive PM (or the negative PM), the lesser (or the greater) the coaches’ tendency to make a change in the organization of their teams. …”

Operation optimization of propane pre-cooled mixed refrigerant LNG Process: A novel integration of knowledge-based and constrained Bayesian optimization approaches by Roba Shady (22048043)

“…At large-scale LNG production (10,000 tons per day), the reduction in the SEC is translated into an 18 MW decrease in compression power, saving approximately 4.7 million $ per year for each C3MR train. …”

Effect of consanguinity on birth weight for gestational age in a developing country by Wakim, Gerard

“…No significant difference was observed in the decrease in birth weight between the first- and second-cousin marriages. …”
Get full text
Get full text
Get full text
Get full text

Predictors of prolonged hospitalization among geriatric trauma patients using the modified 5-Item Frailty index in a Middle Eastern trauma center: an 11-year retrospective study by Husham Abdelrahman (768893)

“…The injury rate for age ≥ 65 was 24 per 10,000 compared to 10 per 10,000 in the younger group age (≥ 55–64). 35% of injuries occurred at home due to falls. …”

Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death by Tohme, Sara

“…This is followed by an increase in lipid peroxidation which peaks at later timepoints and varies between different cell lines. …”
Get full text
Get full text
Get full text

Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis by George Nitzburg (18614989)

“…Second, we examined symptom queries preceding queries on the 12-step program at time lags of 0-7 days, 7-14 days, and 14-30 days, where the probability of asking about a medical symptom was greater in the 30-day time window preceding 12-step program information-seeking as compared to all previous times that the symptom was queried.…”

Reduction of laboratory utilization in the intensive care unit by Diab, Khalil

“…The number of iSTAT laboratory tests per patient-day decreased from 7.37 to an average of 1.16 (P < .001) over the same time period. …”
Get full text
Get full text
Get full text
Get full text

Evapotranspiration and water availability response to climate change in the Middle East and North Africa by Salah Basem Ajjur (14150967)

“…Outcomes reveal that the MENA region is indeed vulnerable to a surge in temperature, which can increase evapotranspiration losses and decrease water availability. Under the shared socioeconomic pathway (SSP2-4.5), the potential evapotranspiration (PET) has been projected to increase throughout the MENA region by up to 0.37 mm per year during the middle of the twenty-first century (2021–2050) and by up to 0.51 mm per year during the end of the twenty-first century (2071–2100). …”

Can Leadership-coaching Mind-set Substitute that of Crisis Management in Higher Education? by Chaika, Oksana

“…The term ‘crisis management’ includes the three stages, i.e. pre-crisis, crisis per se, and post-crisis management in higher education. …”
Get full text

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes by Shadi Nejat (19457212)

“…We previously showed, for the first time, impaired expression of DNAJB3 mRNA and protein in subjects with obesity, which was concomitant with increased metabolic stress. …”

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion by Khoury, Nathalie

“…To assess the effect of kefir on cancer metastasis, wound‑healing and time‑lapse movies, in addition to collagen‑based invasion assay, were used. …”
Get full text
Get full text
Get full text