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441
Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1
Published 2015“…PrAgU2/LF was cytotoxic to five out of nine AML cell lines. Cytotoxicity of PrAgU2/LF appeared to be nonapoptotic and was associated with MAPK activation and urokinase activity because all the PrAgU2/LF-sensitive cell lines showed both uPAR expression and high levels of MEK1/2 phosphorylation. …”
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442
Effect of Crude Oil Products on the Geotechnical Properties of Sandy Soil
Published 2011Get full text
doctoralThesis -
443
Unsustainability in emergent systems
Published 2017“…In this paper we present a detailed case study of the passenger road transport system in the Greater Beirut Area (GBA) where we identify the root causes of the major problems facing the system today and over the long-term. …”
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444
Parallel Algorithm for Hardware Implementation of Inverse Halftoning
Published 2005Get full text
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445
Timing driven genetic algorithm for standard-cell placement
Published 1995Get full text
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446
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447
Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways
Published 2015“…Flow cytometric analysis indicated that both fractions induced sub-G1 phase accumulation and increased apoptotic cell death. Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. …”
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448
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance
Published 2022“…<p>Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia include low sensitivity and specificity, high costs, and a low participation rate. …”
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449
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”
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450
Transient Modeling of a New Solar Distillation Unit for Remote Areas
Published 2016Get full text
doctoralThesis -
451
Corrosion Monitoring Technologies for Reinforced Concrete Structures: A Review
Published 2023“…Due to the vital impact size of corrosion of RC structures in the form of high maintenance demand and an increase in the total life cycle cost, corrosion monitoring, early detection, and timely remediation is considered a necessity and a crucial proactive measure to control corrosion and limit its impact. …”
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452
Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. …”
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453
Cooling Energy and Climate Change Nexus in Arid Climate and the Role of Energy Transition
Published 2023“…Climate change is expected to increase cooling demand, further exacerbating the problem. …”
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454
Flexural strengthening of reinforced concrete beams with CFRP laminates and spike anchors
Published 2024“…This is primarily due to the increase in the fan length and thickness as the anchor's dowel diameter increases.…”
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455
Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres
Published 2024“…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …”
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456
I know you are watching me
Published 2017“…However, limited security resources prohibit full detection coverage on all VMs at all times, which can be exploited by attackers to examine the selective detection strategies and adjust their own attack plans accordingly. …”
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457
Riding the waves: A study of retrun spillovers and inter-sector linkages in US equity markets during the COVID-19 pandemic
Published 2024“…<p>In times of crisis, stock markets experience a significant increase in return volatility, which leads to spillovers across equity sectors. …”
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458
Optimizing Truck Visits to Container Terminals with Consideration of Multiple Drays of Individual Drivers
Published 2018“…The objective of this approach is to show that it is possible to increase the satisfaction of drivers which will maintain the positive effects that the TAS provides to the port. …”
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459
Hepatoprotective Effect of Oleuropein-Rich Extract from Olive Leaves against Cadmium-Induced Toxicity in Mice
Published 2020“…(CD), administered five times during two weeks; and the third group received the same doses of Cd and simultaneously 16 mg/kg b.w. of oleuropein. …”
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460
Over-Pressure Suppresses Ultrasonic-Induced Drug Uptake
Published 2008“…Data also showed a linear increase in membrane permeability with respect to insonation time and intensity. …”
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