Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway by Olfa Khalifa (10914452)

“…<p dir="ltr">Non-alcoholic fatty liver disease (NAFLD) is the leading chronic liver disease worldwide. …”

Boosting the visibility of services in microservice architecture by Ahmet Vedat Tokmak (17773479)

Navigating Turbulent Times: Teachers' Perspectives on School Principal Leadership Styles by Haidar, Nour Amne

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Surgical Strategies for Synchronous Colorectal Liver Metastases in 156 Consecutive Patients by Bouquet, Antoine

“…Background An increasing number of patients with synchronous colorectal liver metastases (CLM) are candidates for resection. …”
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Risk of Malignancy in Indeterminate Liver Nodules Among Patients with Cirrhosis: A Retrospective Cohort Study by Yousef Yahia (19756989)

“…</p><h3>Conclusion</h3><p dir="ltr">Our findings show a higher incidence of HCC in patients with indeterminate liver nodules, increasing over time and reaching 30% at seven years. …”

Tragopogon porrifolius improves serum lipid profile and increases short-term satiety in rats by Zeeni, Nadine

“…Food intake, abdominal fat percentage, blood lipid profile, liver weight and liver enzymes were assessed following 4 weeks of extract intake via drinking water (50, 100, or 250 mg/kg body weight) in standard high-carbohydrate and high-fat dietary conditions. …”
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L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression by Rached, Johnny

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The Threat to Cultural Heritage in Times of Conflict and Its Dynamic Relationship with Gulf Society by Amr Al-Azm (15445301)

The trans-10, cis-12 isomer of conjugated linoleic acid decreases adiponectin assembly by PPARγ-dependent and PPARγ-independent mechanisms by Miller, Jessica R.

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Chemotherapy prior to Hepatic Resection for Colorectal Liver Metastases: Helpful until Harmful? by Abdalla, Eddie K.

“…Steatohepatitis is associated with irinotecan therapy and an increased risk for liver failure and death after hepatic resection. …”
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Systemic Chemotherapy and Two-Stage Hepatectomy for Extensive Bilateral Colorectal Liver Metastases by Chun, Yun Shin

“…Background Two-stage hepatectomy has been proposed for patients with bilateral colorectal liver metastases (CLM). The aim of this study was to compare the outcome of patients with CLM treated with preoperative chemotherapy followed by one- or two-stage hepatectomy. …”
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The effect of foeniculum vulgare seeds on lipidemia, glycemia & liver enzymes. (c2009) by Bitar-Chamas, Rita

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Novel biomarkers for potential risk stratification of drug induced liver injury (DILI) by Mohammed Ibn-Mas’ud Danjuma (13192169)

“…<h3>Background:</h3><p dir="ltr">Drug induced liver injury (DILI) is an increasing cause of acute liver injury especially with increasing need for pharmacotherapy of widening comorbidities amongst our ever-aging population. …”

Noncoding RNAs in Nonalcoholic Fatty Liver Disease: Potential Diagnosis and Prognosis Biomarkers by Olfa Khalifa (10914452)

“…<p>Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease worldwide in part due to the concomitant obesity pandemic and insulin resistance (IR). …”

Time to diagnose and time to surgery in patients presenting with necrotizing fasciitis: a retrospective analysis by Murad S. Alahmad (22457605)

“…In contrast, delayed diagnosis (TTD > 6 h) was significantly associated with increased mortality, regardless of the TTS.</p><h3>Conclusion</h3><p dir="ltr">Timely diagnosis within 6 h is crucial for improving outcomes in NF. …”

Revisiting leishmaniasis in the time of war by Jaber, Amani

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Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030) by Khaled F. Alkaraki (22051967)

“…This study aimed to model past, present, and future LULCC on Land Surface Temperatures in the Greater Amman Municipality (GAM) in Jordan between 1980 and 2030. …”

Chemotherapy Regimen Predicts Steatohepatitis and an Increase in 90-Day Mortality After Surgery for Hepatic Colorectal Metastases by Vauthey, Jean-Nicolas

“…The effect of chemotherapy and liver injury on perioperative outcome was analyzed. …”
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Body surface area and body weight predict total liver volume in Western adults by Vauthey, Jean-Nicolas

“…Computed tomography (CT) is used increasingly to measure liver volume in patients undergoing evaluation for transplantation or resection. …”
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Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases by Glazer, Evan

“…For example, a few years ago an extrahepatic metastasis effectively eliminated surgical resection, but a combination of chemotherapeutic options and surgical techniques has expanded the indications for resection and increased the population of patients who may benefit.1,2 Neoadjuvant chemotherapy has increased the resectability rate by 11% to 37%.1 Unfortunately, greater than 80% of patients undergoing hepatic resection will have recurrences, mostly within the first 2 years.2 Nonetheless, the only hope for cure is resection, and prior surgical dogma based on the number of lesions, size of the tumor-free resection margin, and presence of resectable extrahepatic disease must be questioned.3- 5 The current standard approach to surgical planning is contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) for specific tumor characteristics or contraindications to CT.6 Several series showed that focal extrahepatic disease, an isolated pulmonary lesion, can be safely resected, with 5-year survival rates of 29% to 58%.7,8 In 1 series,7 17 of 30 patients required 3 or more resections. …”
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