Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway by Shilpa Kuttikrishnan (3520079)

“…Our study investigated NSP‐B's antitumor effects on MM cell lines (U266 and RPMI8226) and the involved molecular mechanisms. …”

Simulating blood vessel scaffolds by Nature Research (16552612)

“…According to their simulations, the amount of shear stress is highest at the endoluminal strut surface, where the stent comes into contact with the inner lining of the vessels, but very low at the areas where blood flows in and out of the device. …”

Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy by Al Bostami, Rouba D.

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Electric Grid Resilience Enhancement During Natural Disasters: An Optimization-Based UAV Inspection and Dynamic Crew Dispatch Model by Serag, Yousef

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Assessing continuing education practices and preferences amongst Lebanese hospital pharmacists by Iskandar, Katia

“…Participants noted that barriers to attend live CEs were mainly work responsibilities (76%), travel distance (65.6%), family commitments (48.4%) and scheduling (40.6%). …”
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Vocational education in Jordan. (c1954) by Dajani, Adela Mahmud

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Assessing the perceptions of pharmacists working in Lebanese hospitals on the continuing education preferences by Iskandar, Katia

“…Participants noted that barriers to attend live CEs were mainly work responsibilities (76%), travel distance (65.6%), family commitments (48.4%) and scheduling (40.6%). …”
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Driving and dementia: What factors influence how physicians address the issue? Data from the Swedish Dementia Registry (SveDem) by Dorota Religa (402059)

“…Male gender (OR 2.97, p<0.001) and living alone was associated with an increased likelihood of being reported to the STA. …”

An evaluation of sorter induced cell stress (SICS) on peripheral blood mononuclear cells (PBMCs) after different sort conditions - Are your sorted cells getting SICS? by Gerald Pfister (17075275)

“…Recently, the flow cytometry community has become increasingly aware about the potential negative effects this could have on sorted cells and the term “sorter induced cell stress” (SICS) has been proposed. …”

Differing endometrial expression of calcium modulating transient receptor potential channels by Maryam Ghavideldarestani (11862563)

“…<p dir="ltr">To the editor</p><p dir="ltr">Assisted reproductive techniques (ART) have increased the live birth success rate, but there is still a significant implantation failure rate. …”

Reducing injuries among young drivers: what kind of measures are needed? by Hans-Yngve Berg (19794540)

“…For example, communication campaigns and increased enforcement may be used simultaneously and in particular target young males. …”

Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation by Shilpa Kuttikrishnan (3520079)

“…In this study, we demonstrate that Prist effectively inhibits the proliferation of T-ALL cell lines (Jurkat and Molt 4) by inducing G0/G1 cell cycle arrest and triggering intrinsic and extrinsic caspase-dependent apoptosis. …”

Tumor protease-activated fusion toxins by Abi-Habib, Ralph J.

“…In this study, we demonstrate that DTU2GMCSF is highly potent against AML cell lines in vitro and is not toxic to normal cells both in vitro and in vivo. …”
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Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3 by Harshita Shailesh (14779408)

“…<p></p><div> <p>Protein arginine methyltransferase 5 (PRMT5) activity is dysregulated in many aggressive cancers and its enhanced levels are associated with increased tumour growth and survival. However, the role of PRMT5 in breast cancer remains underexplored. …”

Inositol 1,4,5-Trisphosphate Receptors in Hypertension by Ali H. Eid (5461829)

“…This involves a phenotypic switch of VSMCs as well as an alteration of cytoplasmic Ca²⁺ signaling machinery, a phenomena tightly related to the aging process. Several lines of evidence implicate changes in expression/function levels of IP₃R isoforms in the development of hypertension, VSMC phenotypic switch, and vascular aging. …”

Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway by Kirti.S. Prabhu (17191231)

“…SNG treatment increased Bax/Bcl-2 ratio, which contributed to a leaky mitochondrial membrane leading to cytochrome c release accompanied by caspase activation. …”

A possible culprit for refractory angina by Nature Research (16552612)

“…</p><p>This may implicate lipoprotein(a) as having a causal role in refractory angina, but the findings still need to be confirmed by testing a control group of patients who have coronary heart disease but not refractory angina.</p><p>An increased lipoprotein(a) level is known to be highly heritable, and is believed to promote hardening of the arteries by trapping cholesterol in the inner linings of blood vessels, promoting clot formation, recruiting inflammatory cells, or binding pro-inflammatory phospholipids.…”

Altered regulation of cell migration in IRF6-mutated orofacial cleft patients-derived primary cells reveals a novel role of RhoGTPases in cleft/lip palate development by Al Saneh, Mounir

“…Cleft lip and/or palate (CL/P) affects on average 1 in 700 live births and is considered to be the most common congenital craniofacial birth defect (Setó-Salvia and Stanier 2014). …”
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Globalization and labour markets. (c2004) by Houjeiri, Rana

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Social impact projections for Qatar youth residents from 2022: The case of the IAAF 2019 by Wadih Ishac (18061304)

“…<div><p>While sport is playing an increasingly important role in society in the Middle East, there has been limited research on the perceived social impact of the hosting of major international events in this region. …”