Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation حسب Shilpa Kuttikrishnan (3520079)

"…In this study, we demonstrate that Prist effectively inhibits the proliferation of T-ALL cell lines (Jurkat and Molt 4) by inducing G0/G1 cell cycle arrest and triggering intrinsic and extrinsic caspase-dependent apoptosis. …"

Macular ultrastructural features in amblyopia using high-definition optical coherence tomography حسب Al-Haddad, Christiane Elias

"…Enhanced high-definition single line macular scans of amblyopic eyes were obtained using SD-OCT and compared with fellow eyes. …"
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Tumor protease-activated fusion toxins حسب Abi-Habib, Ralph J.

"…In this study, we demonstrate that DTU2GMCSF is highly potent against AML cell lines in vitro and is not toxic to normal cells both in vitro and in vivo. …"
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Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3 حسب Harshita Shailesh (14779408)

"…In this study, we show that PRMT5 is overexpressed in breast cancer cell lines, and that it promotes WNT/β-CATENIN proliferative signalling through epigenetic silencing of pathway antagonists, <i>DKK1</i> and <i>DKK3</i>, leading to enhanced expression of <i>c-MYC</i>, <i>CYCLIN D1</i> and <i>SURVIVIN</i>. …"

Inositol 1,4,5-Trisphosphate Receptors in Hypertension حسب Ali H. Eid (5461829)

"…This involves a phenotypic switch of VSMCs as well as an alteration of cytoplasmic Ca²⁺ signaling machinery, a phenomena tightly related to the aging process. Several lines of evidence implicate changes in expression/function levels of IP₃R isoforms in the development of hypertension, VSMC phenotypic switch, and vascular aging. …"

Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway حسب Kirti.S. Prabhu (17191231)

"…SNG suppressed cell growth and induced apoptosis via downregulation of the constitutively active JAK/STAT pathway in all the NSCLC cell lines. siRNA silencing of STAT3 in NSCLC cells further confirmed the involvement of the JAK/STAT signaling cascade. …"

Co‐operative learning for Children with an Autistic Spectrum disorder (ASD) in mainstream and special class settings حسب Grey, Ian M.

"…Active task engagement was found to remain relatively stable and passive task engagement was found to decrease for one child and remain stable for the other. …"
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A component analysis of positive behaviour support plans حسب Grey, Ian

"…Conclusion Only treatment acceptability was found to be related to decreases in behavioural frequency. No single intervention component was found to have a greater association with reductions in challenging behaviour…"
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Impact of ICT on Business Continuity and Sustainable Performance: Mediating role of Digital Transformation Culture حسب Mikhael, Michael

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Money and credit policies in small open less-developed economies حسب Shahin, Wassim Naim

"…Some of our results were not in line with the analysis in the existing literature because of the differentiating characteristics of the financial markets in the study.…"
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Comparison of the Incidence and Magnitude of Hyponatremia Among Patients With Poststroke Depression Receiving Either Escitalopram or Sertraline حسب Lina Naseralallah (14146465)

"…Selective serotonin reuptake inhibitors (SSRIs) are frequently used as first‐line antidepressants; however, they have been strongly associated with hyponatremia which, in poststroke patients, can worsen outcomes. …"

The Safety of Novel Therapies in Chronic Lymphocytic Leukemia in the Era of Intermittent Fasting: A Pharmacology-Based Review حسب Maria Benkhadra (19756941)

"…Unfortunately, it is unclear whether the associated risks of tumor lysis syndrome (TLS) and gastrointestinal bleeding (GIB) are increased in IF practitioners receiving NAs. This review explored the literature available on the permissibility of IF in CLL patients undergoing treatment with first-line NAs (FLNAs). …"

<i>Haematococcus pluvialis</i> Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells حسب Nouralhuda Alateyah (21363215)

"…In the present study, we investigated the effects of a methanol crude extract called “T1” of <i>H. pulvialis</i> on cell growth and migration/invasion of the BC cell line MDA-MB-231 in comparison to the fibroblast control cells. …"

National Culture and Leadership in the United Arab Emirates (UAE) حسب MORADKHAN, EALBRA

"…And finally, the study recommends that organisations should hold all the senior executives and line managers accountable for the development of individual managers by owning and executing succession plans.…"
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Effects of natural organic matter on aggregation kinetics of boron nanoparticles in monovalent and divalent electrolytes حسب Liu, Xuyang

"…However, the attachment efficiency kept increasing in the presence of CaCl2 and alginate with the increase in the electrolyte concentration and was greater than unity at >4 mM CaCl2. The destabilization was attributed to bridging of the nanoparticles by the alginate–Ca2+ system. …"
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Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership حسب JASIM, ARIF FADHEL AHMED

"…Research on facilitating innovation in these contexts has found that it involves the reconciliation of conflicting interests among senior team members and achieving organisational ambidexterity through exploring new capabilities while exploiting existing ones. The author’s line of argument is that conceptual skills are likely to play a significant role in ambidexterity leadership for innovation. …"
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Optimum sizing of steam turbines for concentrated solar power plants حسب Poullikkas, Andreas

"…Finally, although the cost of electricity of a CSP plant with capacities greater than 1MWe is significantly reduced to less than 1US$/kWh, currently such technology can only become economically viable through supporting schemes.…"
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The SREBP-dependent regulation of cyclin D1 coordinates cell proliferation and lipid synthesis حسب Arwa Aldaalis (13355328)

"…Consequently, inactivation of SREBP1 in human liver and breast cancer cell lines reduces the expression of cyclin D1 and attenuates Rb phosphorylation. …"

Optimizing microgrid efficiency: Coordinating commercial and residential demand patterns with shared battery energy storage حسب Mohammadreza Gholami (17032317)

"…Moreover, considering DTR for transmission lines, instead of fixed thermal rating, improves the PAR and DPS up to 28.52 % and 41.06 % respectively. …"

Composite hydrogels from carrageenan-cl-carboxymethyl chitosan–PVA incorporated ZiF-8 as dressing material for wound healing applications حسب Tooba Yasin (19131382)

"…The biocompatibility of the composite hydrogels has been evaluated using fibroblast cell lines (<i>3T3</i>) after different time intervals (24–72 h), and it was found that increasing ZiF-8 caused the mature and spread cell morphology with increasing cell viability and proliferation under controlled in vitro conditions. …"