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Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…Finally, as a definitive and specific way to modulate SLFN11 expression we implemented SLFN11 dCas9 (dead CRISPR associated protein 9) systems to specifically increase or decrease SLFN11 expression.</p><h3>Results</h3><p dir="ltr">After confirming the previously reported correlation between methylation of SLFN11 promoter and its expression across multiple cell lines, we showed in-vitro that decitabine and IFN-γ could increase moderately the expression of SLFN11 in both BT-549 and T47D cell lines. …”
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An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im...
Published 2020“…In terms of United Arab Emirates University (UAEU), there has been a decrease in STEM programs enrolment, while STEM graduates in UAEU has stayed steady at 1/3 STEM majors compared to 2/3 non-STEM programs. …”
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The Impact of a Computerized Potassium Alert on Adverse Drug Events and Pharmacists' Interventions
Published 2010“…Conclusions: Implementation of a computerized pharmacy alert resulted in a statistically significant decrease in adverse drug events related to hyperkalemia in our institution. …”
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Symptoms of depression and anxiety in anorexia nervosa
Published 2014“…Increase in the TRP/LNAA ratio was correlated with a decrease in depressive symptoms. In addition, there was a positive correlation between serotonin levels and symptoms of both anxiety and depression at discharge. …”
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Cycling and regeneration of adsorbed natural gas in microporous materials
Published 2017“…Cycling and regeneration study of sorbent for hundreds of cycles has been investigated. The evolution of storage capacity is measured after successive cycling using a custom-built Sievert apparatus. …”
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The effect of foeniculum vulgare seeds on lipidemia, glycemia & liver enzymes. (c2009)
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Subarachnoid hemorrhage associated with tadalafil
Published 2011“…There was no decrease in the level of consciousness, no focal neurologic deficit, and no convulsive activity. …”
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A Comparative study of Technical Efficiency in GCC Islamic Financial Institutions during the Global financial Crisis using Malmquist-Type Data Envelopment analysis
Published 2013“…Islamic banking is gaining more importance, especially after the latest global banking crisis. This importance is because Islamic financial Institutions (IFIs) are believed to have not been affected by the year 2007-2008 financial meltdown. …”
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Estimation of Virtual Trust on Driverless Cars using Type-1 Fuzzy logic
Published 2024“…These vehicles boost confidence, increase road capacity, and decrease traffic accident. …”
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Dissecting the signaling pathways regulating the vascular endothelial growth factor (VEGF) in brain tumor cells. (c2017)
Published 2017“…The knockdown of the Rho GTPases, RhoA and RhoC separately had no effect on VEGF expression neither after hypoxia nor after EGF stimulation. However, when both RhoA and RhoC were knocked down, VEGF expression decreased after EGF stimulation. …”
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Graphite and metal nitrate-infused HDPE composites for enhanced thermal performance in energy-efficient building envelopes
Published 2025“…Analysis such as Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA), Scanning Electron Microscopy (SEM), and dielectric spectroscopy analyses further revealed extensive interaction between filler matrices, a decrease in phonon scattering, and a positive increase in crystallinity which led to the improved thermal performance.The TGA results showed that the composite exhibited greater thermal stability, and the residue mass after the decomposition process was 9%, indicating increased carbonization and structural integrity. …”
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Visitors off the trail: Impacts on the dominant plant, bryophyte and lichen species in alpine heath vegetation in sub-arctic Sweden
Published 2021“…With a greater decrease in taller forbs and shrubs than in graminoids and prostrate plants, a greater decrease in lichen than in bryophyte species, and a change in vegetation composition. …”
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Modulation of Chronic Stress Outcomes by Dietary Sweeteners: A Comparative Study of Sucrose and Aspartame in Mice
Published 2025“…Background: Dietary sweeteners may modulate physiological and behavioral responses to stress. It has been suggested that sucrose consumption attenuates stress-induced cortisol secretion, whereas aspartame has been reported to increase activity of glucocorticoids and anxiety-like behavior in rodents Aim: The present study aimed to assess the differential effects of sucrose and aspartame on the physiological and behavioral response in chronic stress in mice. …”
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Effect of Anthrax Lethal Toxin on Activation of MAPK Pathway and Autophagy in AML Cell Lines
Published 2021“…Flow cytometry analysis of downstream effectors of MEK showed decrease in phosphorylation of ERK and its downstream effectors only at early time points in sensitive cell lines. …”
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Investigating the causes and drivers of food waste in the hospitality sector in Dubai-UAE. Toward implementing food waste prevention strategies.”
Published 2022“…Goal number 12 of these 17 SDGs focuses on making consumption and production reasonable to lower the use of natural resources and decrease the waste generated consequently. The food loss and waste problem have been the focus of individuals and governments in the late few years; this is referred to as its effects on the sustainable vision of the countries as well as its impact on the social, economic and environmental sides of them. …”
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Evidence-based safety education and training for traffic injury prevention
Published 2015“…Bicycle skill training for children and youth may increase their safety knowledge, but not necessarily improve their behavior or decrease their injury rates. …”
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Gaining or Losing Team Ball Possession: The Dynamics of Momentum Perception and Strategic Choice in Football Coaches
Published 2019“…Nonetheless, both variables displayed asymmetrical effects, in the sense that: (1) the strength of positive PM appeared to be easier to decrease than to increase; and (2) the greater the positive PM (or the negative PM), the lesser (or the greater) the coaches’ tendency to make a change in the organization of their teams. …”
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Impact of aluminium acetate particles size on the gelation kinetics of polyacrylamide‐based gels: Rheological and molecular simulation study
Published 2023“…The addition of bentonite at low crosslinker concentrations (0.5–1 wt.%) did not decrease the gel strength of 7 wt.% PAM/1 wt.% AlAc significantly. …”