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541
A new perspective on cardiovascular drift during prolonged exercise
Published 2021“…Cardiovascular drift has been debated for a long time. Although the exact mechanisms underlying cardiovascular drift are still unknown, two theories have been proposed. …”
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542
Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice
Published 2024“…<p dir="ltr">Chronic use of synthetic <u>cannabinoids</u> (SCs) has been associated with cognitive and behavioural deficits and an increased risk of neuropsychiatric disorders. …”
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543
Fanconi–Bickel Syndrome: A Review of the Mechanisms That Lead to Dysglycaemia
Published 2020“…Missense, nonsense, frame-shift (fs), in-frame indels, splice site, and compound heterozygous variants have all been identified in SLC2A2 gene of FBS cases. Approximately 144 FBS cases with 70 different SLC2A2 gene variants have been reported so far. …”
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544
Strengthening of thin reinforced concrete slabs with CFRP laminates
Published 2016“…Over the years, engineers and researchers have been working continuously to reduce the dead loads on buildings by reducing the sizes of structural elements. …”
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545
Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic...
Published 2021“…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression.…”
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546
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547
Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2...
Published 2024“…For younger demographics (ie, those aged 0–4 years and 5–14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …”
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548
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549
Fractionation and phytochemical composition of an ethanolic extract of Ziziphus nummularia leaves: antioxidant and anticancerous properties in human triple negative breast cancer c...
Published 2024“…<p dir="ltr">Natural products have long been utilized in traditional medicine as remedies to improve health and treat illnesses, and have had a key role in modern drug discovery. …”
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550
Thymoquinone from Nigella sativa seeds promotes the antitumor activity of noncytotoxic doses of topotecan in human colorectal cancer cells in vitro
Published 2016“…In conclusion, thymoquinone increased the effectiveness of the chemotherapeutic reagent topotecan by inhibiting proliferation and lowering toxicity through p53- and Bax/Bcl2-independent mechanisms.…”
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551
Sentiment analysis for Arabizi in social media. (c2015)
Published 2015“…With the vast increase of social media users over the past few years, millions of product reviews are discussed and posted in online forums and social media such as Facebook and Twitter. …”
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masterThesis -
552
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553
Software quality improvement model for small organizations. (c2000)
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masterThesis -
554
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555
Nebulized fentanyl for respiratory symptoms in patients with COVID-19 (ventanyl trial)
Published 2022“…Some methods such as nebulized lidocaine, magnesium sulfate, and systemic opioids have been used to manage the respiratory symptoms. It has been previously shown that fentanyl nebulizer has beneficial effect in improving shortness of breath in patients with chronic obstructive pulmonary disease. …”
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556
Stochastic Programming for Hub Energy Management Considering Uncertainty Using Two-Point Estimate Method and Optimization Algorithm
Published 2023“…<p dir="ltr">To maximize energy profit with the participation of electricity, natural gas, and district heating networks in the day-ahead market, stochastic scheduling of energy hubs taking into account the uncertainty of photovoltaic and wind resources, has been carried out. This has been done using a new meta-heuristic algorithm, improved artificial rabbits optimization (IARO). …”
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557
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558
Towards the development of an integrated model for examining the determinants affecting the use of Queue Management Solutions in Healthcare
Published 2021“…A total of 1,768 studies have been reviewed, and 142 studies were found eligible and considered in the analysis. …”
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559
The effects of texting on students' spelling skills. (c2014)
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masterThesis -
560
Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute...
Published 2023“…However, given that MMP9 was found not to be expressed in the sensitive cell lines, we were able to exclude its expression as a requirement for cytotoxicity. …”
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masterThesis