Characterizing the Effect of Arginine Deprivation on Autophagic Response in Breast Cancer cells حسب Haidar, Fatemah

"…Residual ASS1 tumor expression corelated with increased metastasis and decreased survival in patient luminal A, Her2+ and triple-negative breast cancer. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells حسب Shilpa Kuttikrishnan (3520079)

"…<p>Neosetophomone B (NSP–B), a meroterpenoid fungal secondary metabolite, was investigated for its anticancer potential in leukemic cell lines (K562 and U937). NSP-B treatment of leukemic cells suppressed cell viability by triggering apoptotic cell death. …"

Investigating the Fluorescence Quenching of Doxorubicin in Folic Acid Solutions and Its Relation to Ligand-Targeted Nanocarriers حسب Husseini, Ghaleb

"…The folate receptor is widely expressed on the surface of several cell lines and tumors; including ovarian, brain, kidney, breast, and lung cancers. …"
احصل على النص الكامل

Scalable Generation of Mesenchymal Stem Cells and Adipocytes from Human Pluripotent Stem Cells حسب Manale Karam (3619412)

"…We showed that short exposure of multiple hPSC lines (hESCs/hiPSCs) to 10 μM RA dramatically enhances embryoid body (EB) formation through regulation of genes activating signaling pathways associated with cell proliferation, survival and adhesion, among others. …"

Theoretical Framework for Effective Communication Processes for the Agile Project Management Approach in the UAE Utility Sector حسب Afifi, Mutasim

احصل على النص الكامل
احصل على النص الكامل

Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE حسب SHAREEF, SUNDUS LUAY

"…The variation along the short direction of the urban block has a greater positive effect and the saving in cooling energy consumption reaches 4.6 %. …"
احصل على النص الكامل

Cytotoxicity of Anthrax Lethal Toxin to Human Acute Myeloid Leukemia Cells Is Nonapoptotic and Dependent on Extracellular Signal-Regulated Kinase 1/2 Activity حسب Abi-Habib, Ralph J.

"…We tested potency of LeTx on a panel of 11 human AML cell lines. Seven cell lines showed cytotoxic responses to LeTx. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes حسب Rizk, Sandra

"…The percent reduction in proliferation was very significant, and was dose-, and time-dependent. In both cell lines, kefir exhibited its antiproliferative effect by downregulating TGF-α and upregulating TGF-β1 mRNA expression. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Anticancer and antioxidant effects of tragopogon porrifolius extract. (c2011) حسب Tenkerian, Clara A.

احصل على النص الكامل
احصل على النص الكامل

PSA-activated proaerolysin as a prostate specific cancer therapy حسب Abi-Habib, Ralph

"…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Deep Learning-Based Fault Diagnosis of Photovoltaic Systems: A Comprehensive Review and Enhancement Prospects حسب Majdi Mansouri (16869885)

"…These faults may affect the different system components such as PV modules, connection lines, converters/inverters, which can lead to a decrease in the efficiency, performance, and further system collapse. …"

Snake venom in conjugation with silica nanoparticles: an emerging cancer therapy حسب Duaa Azam (22502048)

"…<i>In vitro</i> investigations on cancer cell lines revealed a considerable increase in cytotoxicity and induction of apoptosis as compared to free snake venom, with greater selectivity for malignant cells. …"

Targeting human acute myeloid leukemia cells using human recombinant arginase I (Co) - PEG5000 [HuArgl (Co) - PEG5000] - induced arginine depletion. (c2013) حسب Tanios, Rita Farid

احصل على النص الكامل
احصل على النص الكامل

Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways حسب Shehaby, Wassim N.

"…Flow cytometric analysis indicated that both fractions induced sub-G1 phase accumulation and increased apoptotic cell death. Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance حسب Ajaz A. Bhat (12984701)

"…<p>Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia include low sensitivity and specificity, high costs, and a low participation rate. …"

Impacts of On-Grid Solar PV on Distribution Networks and Potential Solutions: A Case Study in the Region of Zahle حسب Korkmaz, Jessica

"…Recent years have witnessed an increase in the installation of solar photovoltaic-based distributed generators or PV DGs mainly in countries with high solar potential such as Lebanon. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…The pro-apoptotic effect upon combination of topotecan with andrographolide was further observed using annexin V/PI staining; even though andrographolide alone did not alter cell survival, however, when applied to the cells prior to topotecan treatment, the number of apoptotic cells increased from 16% to 57%. Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Enhanced cellular uptake and photochemotherapeutic potential of a lipophilic strained Ru(II) polypyridyl complex حسب Mehanna, Stephanie

"…When compared to cisplatin, the photoproducts were more potent against all tested cell lines, implying that the complex acquired significant chemotherapeutic potential upon irradiation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Hydrophobic Ionic Liquids for Efficient Extraction of Oil from Produced Water حسب Liaqat, Shehzad

"…The extraction efficiency was found to increase with increasing cation alkyl chain length from C2 to C10. …"
احصل على النص الكامل

Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 حسب Joan B Soriano (6458528)

"…Death rates due to interstitial lung disease and pulmonary sarcoidosis were greater than those due to pneumoconiosis in all super-regions. …"