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241
Tuberculosis following programmed cell death receptor-1 (PD-1) inhibitor in a patient with non-small cell lung cancer. Case report and literature review
Published 2022“…Nonetheless, tuberculosis (TB) reactivation during their use is increasingly recognized and reported. Herein, we present a 58-year-old lady with advanced non-small cell lung cancer (NSCLC) ALK-negative, EGFR wild, and PD-L1 immune histochemistry (IHC) strongly positive in 95% of tumor cells, on ongoing treatment with Pembrolizumab as a first-line monotherapy. …”
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242
Dynamic Biomarkers of Response to Anti-Immune Checkpoint Inhibitors in Cancer
Published 2021“…To date, immune check-point inhibitors have been approved as first or second line therapy options in a broadening range of metastatic cancer and increasingly explored in the treatment of early stage tumors. …”
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243
PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer
Published 2019“…In this study, we investigated the molecular mechanisms by which the human TNBC cell line MDA-MB-231, expressing PD-L1, responds to atezolizumab, using RNA-Seq. …”
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244
Prevalence and global trends of polypharmacy in patients with chronic kidney disease: A systematic review and meta-analysis
Published 2023“…In line with the therapeutic guidelines, managing CKD and its complications necessitates prescribing multiple medications, which predisposes patients to polypharmacy. …”
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245
Need for Affect, Problematic Social Media Use and the Mediating Role of Fear of Missing Out in European and Arab Samples
Published 2023“…<h3>Purpose </h3><p dir="ltr">The growing awareness and concern about the excessive use of social media have led to an increasing number of studies investigating the underlying factors contributing to this behavior. …”
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246
A Model of Telecommunication Sector Development and Economical Growth in GCC Countries: A Case Study of UAE
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247
The impact of cultural diversity on project management communication
Published 2022“…The results of the study are in line with some previous research, who said that when examined in terms of age, gender, and ethnicity, having a diverse workforce has a positive impact on the organization's performance. …”
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248
Effects of selenium in comparison to exendin-4 on the expression of GLP-1R, IRS-1 and preproinsulin in the pancreas of diabetic rats
Published 2016“…It binds and activates GLP-1R with greater potency than GLP-1 and is used in the treatment of diabetes mellitus. …”
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249
Epidemiological and clinical characteristics of fall-related injuries: a retrospective study
Published 2020“…Although the rate of fall-related injuries decreased over the years, the average number of patients per year remained high accounting for 32% of the hospitalized patients with moderate to severe injuries. …”
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250
Trends in criminal convictions in Japan for vehicle collisions where one driver suffers from an epileptic seizure
Published 2015“…To reduce collisions to an even greater degree, this type of collision should be prevented. …”
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251
The synthetic cathinones MDPHP and MDPV: Comparison of the acute effects in mice, in silico ADMET profiles and clinical reports
Published 2024“…Our results substantiated that MDPHP and MDPV similarly affect sensorimotor and behavioural responses in mice, importantly increased locomotion and induced aggressive behaviour, and, at higher dosage, increased heart rate and blood pressure. …”
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252
Nonlinear Control of Brushless Dual-Fed Induction Generator With a Flywheel Energy Storage System for Improved System Performance
Published 2025“…After optimization, the SMC settling time was significantly reduced from 0.7 seconds to 19.97 milliseconds, achieving a 96.9% improvement in response speed, while its steady-state error decreased from 0.48 to 0.06, marking an 87.5% reduction in tracking error. …”
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253
Vitamin D Association With Macrophage-Derived Cytokines in Polycystic Ovary Syndrome: An Enhanced Risk of COVID-19 Infection?
Published 2021“…Vitamin D deficiency was associated with decreased CD80 and IFN-γ in PCOS and IL-12 in both groups (p<0.05). …”
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254
Effects of COVID-19 on Autism Spectrum Disorder in Qatar
Published 2024“…Parents also reported decreased access to family and social support networks, as well as decreased quality of clinical and community support. …”
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255
Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death
Published 2023“…This is followed by an increase in lipid peroxidation which peaks at later timepoints and varies between different cell lines. …”
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masterThesis -
256
A Numerical Study of Heat Transfer and Fluid Flow in a Channel with an Array of Pin Fins in Aligned and Staggered Configurations
Published 2018“…However, as Reynolds number is increased, the maximum average fin Nusselt number value moved to the second row of fins, a fact that was attributed to the speeding flow field by the first row of fins. The percentage decay of Nusselt number with respect to the number of fin rows N showed a large dependence on Reynolds number, the stacking configuration, and the dimensionless spacing, S*. …”
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257
Clinical characteristics and outcome of children with acute cryptorchid testicular torsion: A single-center, retrospective case series study
Published 2024“…Preoperative color Doppler ultrasonography revealed absent or decreased testicular blood flow in the affected testes in 7/8 of patients. …”
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258
COVID-19 biomarkers for severity mapped to polycystic ovary syndrome
Published 2020“…These protein panels target biological processes involved in vessel damage, platelet degranulation, the coagulation cascade and the acute phase response [1], with greater protein changes dependent on the COVID-19 severity. …”
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259
Chronic reduction of store operated Ca<sup>2+</sup> entry is viable therapeutically but is associated with cardiovascular complications
Published 2022“…The hypertension is not due to increased vascular smooth muscle contractility or vascular remodelling.…”
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260
Machine Learning-Based Management of Electric Vehicles Charging: Towards Highly-Dispersed Fast Chargers
Published 2020“…<p dir="ltr">Coordinated charging of electric vehicles (EVs) improves the overall efficiency of the power grid as it avoids distribution system overloads, increases power quality, and decreases voltage fluctuations. Moreover, the coordinated charging supports flattening the load profile. …”