A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia... by Abi-Habib, Ralph J.

“…The activity of this toxin was then tested on a larger group of 13 human AML cell lines; 5 of the 13 cell lines were sensitive to DTU2GMCSF. …”
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Expanding the donor pool by Ramos, Emilio

“…In 1990, one-year graft survival rates were about 70%; by 2000, they were greater than 90% (United States Renal Data System, 2001). …”
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Isolation and study of Lipase activity of an olive oil degrading Thermoactionomyces SP. (c2002) by Al Khudary, Rami

“…No traces of triolein were detected after 36 hours of cultivation. A concentration of 10% (v/v) olive oil did not inhibit its growth. …”
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Bond durability of sand coated and ribbed basalt FRP bars embedded in high-strength concrete by Abathar Al-Hamrani (16494884)

“…However, specimens with high-strength concrete achieved most of or above their maximum bond strength after the descending stage, while those with normal-strength concrete showed a decrease in bond strength to an approximately constant value with continuous slip. …”

Simultaneous Bilateral Neck of Femur Fracture in a Young Adult with Underlying Metabolic Disturbances by Eslam Alkaramani (14570439)

“…We report this rare case of bilateral neck of femur fracture in a young adult after a generalized seizure attack with underlying metabolic disturbances. …”

Subarachnoid hemorrhage associated with tadalafil by Sheikh-Taha, Marwan

“…Inhibition of the PDE5 isoenzyme, which is responsible for degradation of cyclic guanosine monophosphate in the corpus cavernosum, will ultimately enhance the effect of nitric oxide and, consequently, the relaxation of the vascular smooth muscle in the corpus cavernosum and penile erection after sexual stimulation. Tadalafil is the longest-acting PDE5 inhibitor, with an elimination half-life of 17.5 hours and up to 36 hours’ duration of effect. …”
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Interactions between riluzole and ABCG2/BCRP transporter by Milane, Aline

“…Assays on mdr1a (−/−) mice and BeWo cells showed a higher uptake of riluzole when pretreated with a BCRP inhibitor. After repeated doses of riluzole, BCRP activity was increased in CF1 mdr1a (−/−) mice, riluzole uptake was decrease and both BCRP expression and activity were increased in BeWo cells. …”
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Characterization of the Potency and Mechanism of Action of a Novel Dual-Selective Intermolecularly Complemented Version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Breas... by Basala, Sobhiya

“…Results show that UACC-2087 cell line expresses the three proteases and upon treatment, the levels of expression were not consistent. …”
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Strategie trading company (STC). (c1994) by Rbeiz, Marc

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PSA-activated proaerolysin as a prostate specific cancer therapy by Abi-Habib, Ralph

“…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …”
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Snake venom in conjugation with silica nanoparticles: an emerging cancer therapy by Duaa Azam (22502048)

“…<i>In vitro</i> investigations on cancer cell lines revealed a considerable increase in cytotoxicity and induction of apoptosis as compared to free snake venom, with greater selectivity for malignant cells. …”

Full Film, Boundary Lubrication and Tribochemistry in Steel Circular Contacts Lubricated with Glycerol by Habchi, W.

“…In fact, water produced in the lubricant decreases traction forces due to the drastic decrease of the viscosity of glycerol with water addition.…”
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The effects of a change in the point system on immigration by Chemin, Matthieu

“…In line with the initial objective, we find more French-speaking immigrants with bachelor’s degrees, and no worsening in labor market outcomes after the reform. …”
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Effect of acute and chronic moderate alcohol consumption on fasted and postprandial lipemia in the rat by Daher, Costantine F.

“…Blood samples were collected from animals in either the fasted state or after being loaded with the fat load as described above. …”
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Subsarcolemmal cAMP signals monitored by cyclic nucleotide gated channels in hypertrophied cardiac myocytes by Abi-Gerges, Aniella

“…This channel is gated by cAMP and thus allow to follow cAMP dynamics by recording the associated cationic current (ICNG) with the whole cell patch clamp technique 24 h after infection. Cumulative concentrationresponse curve to the non-selective E-adrenergic agonist isoprenaline (Iso) indicated a 33% decrease of the maximal cAMP accumulation produced by Iso while the effect of the hydrosoluble forskolin analog, L-858051 at a saturating concentration (100 µM) was unchanged between the two groups. …”
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Renal Function Decline in Recipients and Donors of Kidney Grafts by Bahous, Sola Aoun

“…Background/Aims: Renal function decreases over time as a result of reduction in the number of functioning nephrons with age. …”
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Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia by Shilpa Kuttikrishnan (3520079)

“…Curcumin induces apoptosis in B-Pre-ALL cell lines via activation of caspase-8 and truncation of BID. …”

Water-pipe smoking promotes epithelial–mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways by Khaled W. Sadek (14153196)

“…<p>With the increasing popularity of water-pipe smoking (WPS), it is critical to comprehend how WPS may affect women’s health. …”

The impact of maternal care on child development by Sayour, Nagham

“…Results show that treated children enjoy an increase of 3.6 h per week in the time they spend with their mothers, mainly due to a decrease in the time spent in non-institutional care. …”
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Optimizing Functional Unit Binding During HighLevel Synthesis by Ouaiss, Iyad

“…This article proposes a solution that incorporates a simulated annealing approach after binding operations to functional units in the goal of reducing overall area. …”
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