Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... حسب Muhanad Alhujaily (11630107)

"…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression.…"

"Development of Authentic Annual and Seasonal Lightning Thunderstorms Day Maps for Saudi Arabia" حسب Shwehdi, M. H.

"…The southern region in general, and especially the cities of Abha, Taif and Al-Baha, has shown greater numbers of thunderstorm days all year round. …"
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"Thunderstorm distribution and frequency in Saudi Arabia" حسب Shwehdi, M. H.

"…The southern region in general, and especially the cities of Abha, Taif and Al-Baha, has shown greater numbers of thunderstorm days all year round. …"
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The Impact of a Computerized Potassium Alert on Adverse Drug Events and Pharmacists' Interventions حسب Mansour, Hanine

"…Methods: An alert was built into the pharmacy computer system, which warned pharmacists about a potassium level greater than 5.1 mEq/L when processing an order that could increase potassium. …"
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Rebound effects undermine carbon footprint reduction potential of autonomous electric vehicles حسب Nuri C. Onat (14779093)

"…<p dir="ltr">Autonomous vehicles offer greater passenger convenience and improved fuel efficiency. …"

Curcumin encapsulated colloidal amphiphilic block co-polymeric nanocapsules حسب Bechnak, Linda

"…The cytotoxicity of curcumin and colloidal nanocapsules was assessed using human derived immortalized cell lines (A549 and A375 cells) in the presence and absence of light irradiation. …"
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Accelerating Care: Enhancing Patient Satisfaction through a Quality Initiative in the Obstetrics and Gynaecology Emergency Department at Al Wakra Hospital, Qatar حسب Lolwa Al Ansari (18466227)

"…Notably, there was a remarkable decrease in patients who Left Without Being Seen (LWBS) and in absconded patient rates from 2020 to 2023 (Figure 2).…"

Analyzing the Influence of Climate and Anthropogenic Development on Vegetation Cover in the Coastal Ecosystems of GCC حسب Abhilash Dutta Roy (22466830)

"…Our results revealed significant changes in land cover, as seen by an increase in artificial built-up areas by 15.5% in two decades and a corresponding decrease in bareland and dense vegetation. …"

Ambulatory general urgent clinic: an initiative at the time of COVID-19 pandemic حسب Abdullah Al-Hothi (18505290)

"…The average waiting time to be seen for an urgent referral in our Department’s Physician Clinics is 14 to 21 days. …"

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes حسب Shadi Nejat (19457212)

"…Three DNAJB3 knockout (KO) lines were generated (KO 30, 44 and 47), using CRISPR-Cas9. …"

Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death حسب Tohme, Sara

"…This is followed by an increase in lipid peroxidation which peaks at later timepoints and varies between different cell lines. …"
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Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells حسب Shilpa Kuttikrishnan (3520079)

"…<p>Neosetophomone B (NSP–B), a meroterpenoid fungal secondary metabolite, was investigated for its anticancer potential in leukemic cell lines (K562 and U937). NSP-B treatment of leukemic cells suppressed cell viability by triggering apoptotic cell death. …"

Scalable Generation of Mesenchymal Stem Cells and Adipocytes from Human Pluripotent Stem Cells حسب Manale Karam (3619412)

"…Disruption of cell adhesion induced the subsequent differentiation of the highly expanded RA-derived EB-forming cells into a pure population of multipotent MSCs (up to 1542-fold increase in comparison to RA-untreated counterparts). …"

Investigating the Fluorescence Quenching of Doxorubicin in Folic Acid Solutions and Its Relation to Ligand-Targeted Nanocarriers حسب Husseini, Ghaleb

"…The folate receptor is widely expressed on the surface of several cell lines and tumors; including ovarian, brain, kidney, breast, and lung cancers. …"
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Theoretical Framework for Effective Communication Processes for the Agile Project Management Approach in the UAE Utility Sector حسب Afifi, Mutasim

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Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) حسب El Jawhari, Yassmine

"…Cytotoxicity of [HuArgI (Co)-PEG5000] was tested on two GBM cell lines, namely A172 and U251. Both cell lines showed increased sensitivity at longer incubation periods of [HuArgI (Co)-PEG5000] treatment with IC50 values in the pM range, a result attributable to the arginine auxotrophy expressed in those two cell lines. …"
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Evaluation of pretreatment and membrane configuration for pressure-retarded osmosis application to produced water from the petroleum industry حسب Dareen Dardor (17052381)

"…PRO is typically considered with seawater/river water pairings however greater energy can be recovered from hypersaline solutions including produced water (PW) from the petroleum industry. …"

Graphite and metal nitrate-infused HDPE composites for enhanced thermal performance in energy-efficient building envelopes حسب Mohammad Amir Khan (23770803)

"…Analysis such as Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA), Scanning Electron Microscopy (SEM), and dielectric spectroscopy analyses further revealed extensive interaction between filler matrices, a decrease in phonon scattering, and a positive increase in crystallinity which led to the improved thermal performance.The TGA results showed that the composite exhibited greater thermal stability, and the residue mass after the decomposition process was 9%, indicating increased carbonization and structural integrity. …"

Western diet induces mild metabolic impairment and aggravates neuropathology in an experimental mouse model of traumatic brain injury حسب Judith, Nwaiwu

"…Individuals with TBI have a greater risk of mortality from associated chronic diseases than the general population. …"
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A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia... حسب Abi-Habib, Ralph J.

"…The activity of this toxin was then tested on a larger group of 13 human AML cell lines; 5 of the 13 cell lines were sensitive to DTU2GMCSF. …"
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