Enhanced cellular uptake and photochemotherapeutic potential of a lipophilic strained Ru(II) polypyridyl complex حسب Mehanna, Stephanie

"…When compared to cisplatin, the photoproducts were more potent against all tested cell lines, implying that the complex acquired significant chemotherapeutic potential upon irradiation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance حسب Ajaz A. Bhat (12984701)

"…<p>Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia include low sensitivity and specificity, high costs, and a low participation rate. …"

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications حسب Pramod Darvin (153341)

"…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"

Hydrophobic Ionic Liquids for Efficient Extraction of Oil from Produced Water حسب Liaqat, Shehzad

"…The extraction efficiency was found to increase with increasing cation alkyl chain length from C2 to C10. …"
احصل على النص الكامل

Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres حسب Radha, Remya

"…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …"
احصل على النص الكامل

A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters حسب Abdelrahman M. Awad (16932519)

"…As the drill pipe rotational speed increased, the pressure drop decreased slightly until a critical rotatory speed was reached, thereafter, the pressure drop increased markedly. …"

Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans حسب Kirti S. Prabhu (4246144)

"…In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). …"

The distribution of toxic sources in Louisiana حسب Djoundourian, Salpie Sarkis

"…Furthermore, the greater the percentage of blacks in a community, the greater the reductions in discharges. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Urtica dioica extract and its impact on blood lipids, glycemia & inflammation in the rat model. (c2005) حسب Baroudy, Karmen George

احصل على النص الكامل
احصل على النص الكامل

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

"…Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Recovery of business intelligence systems حسب Haraty, Ramzi A.

"…In the best case, the proposed algorithm requires 0.43 ms, which is 86 times faster than the fastest recent work. This is a significant reduction of execution time compared with other available approaches. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Investigating the Therapeutic Effects of Small Molecule Imipridones In Pediatric Neuroblastoma حسب El Soussi, Sarra

"…MYCN expression was significantly abrogated in the IMR-32 cell line with either drug treatment. The protein expression of Sox-2, Oct-4, FABP5 and HMGA1 was significantly reduced whereas cleaved PARP1 and caspase-3 and p-H2AX was increased 48 h after drug treatment in the MYCN-amplified IMR-32 cell line. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma حسب Peter Kubatka (11008854)

"…However, only in lower dose of sumac were significant decreases in the expression of oncogenic miR210 and increase of tumor-suppressive miR145 (miR21, miR22, and miR155 were not changed) observed. …"

Analysis of Innovative Vapor Compression and Thermal Energy Storage Systems Using Alternative Refrigerants حسب Morad, Bahaa

احصل على النص الكامل

Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy حسب Nassiba Taib (14557385)

"…</p><h2>Methods</h2><p dir="ltr">We compared the effect of DAC in primary 1076 Col and metastatic 1872 Col cell lines isolated and generated from patients’ tumor tissues. …"

Evidence-based safety education and training for traffic injury prevention حسب Abbas Motevalian (338825)

"…Stronger GDL programs achieve greater fatality reduction. A systematic review on the effects of post-license driver education, provides no evidence of its effects on preventing road traffic crashes or injuries. …"

Utilization of the internet for physical activity and diet information and its influence on pregnant women’s lifestyle habits in Qatar حسب Ayman Al-Dahshan (8962568)

"…</p><h3>Conclusion</h3><p dir="ltr">Many pregnant women use the internet to access information about PA and diet, and greater use is associated with more positive lifestyle changes. …"

Thymoquinone from Nigella sativa seeds promotes the antitumor activity of noncytotoxic doses of topotecan in human colorectal cancer cells in vitro حسب Khalife, Rana

"…In conclusion, thymoquinone increased the effectiveness of the chemotherapeutic reagent topotecan by inhibiting proliferation and lowering toxicity through p53- and Bax/Bcl2-independent mechanisms.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Sentiment analysis for Arabizi in social media. (c2015) حسب Tobaili, Taha

"…With the vast increase of social media users over the past few years, millions of product reviews are discussed and posted in online forums and social media such as Facebook and Twitter. …"
احصل على النص الكامل
احصل على النص الكامل

Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis حسب George Nitzburg (18614989)

"…Second, we examined symptom queries preceding queries on the 12-step program at time lags of 0-7 days, 7-14 days, and 14-30 days, where the probability of asking about a medical symptom was greater in the 30-day time window preceding 12-step program information-seeking as compared to all previous times that the symptom was queried.…"