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621
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…Recent studies revealed that enhanced PD-L1 expression in cancer stem cells is linked to immune evasion. Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …"
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622
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623
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624
Hardware Trojan Mitigation Technique in Network-on-Chip (NoC)
منشور في 2023"…However, insufficient effort has been made for hardware Trojans (HTs) in the network-on-chip. …"
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625
3D FEM Model on the Parameters’ Influence of EPB-TBM on Settlements of Single and Twin Metro Tunnels During Construction
منشور في 2022"…Then the simulation has been performed on the influence of effective parameters of EPB-TBM on the surface settlements throughout excavation. …"
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626
The impact of metformin therapy for gestational diabetes on fetal growth in women with risk factors for fetal growth restriction- a registry-based study from Qatar
منشور في 2023"…Numerous studies have demonstrated that metformin therapy for GDM offers advantages including a reduced risk of macrosomia, neonatal hypoglycemia, and admission to neonatal intensive care units (NICU). However, its use has been linked to fetal growth restriction (FGR) as well. …"
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627
Mitigating the impact of cultural diversity on the innovation process in the private sector in Dubai
منشور في 2017"…The economy in the Middle East countries has been on the rise in the recent years, and therefore, the management in various departments and government sector have been in search for labour from different parts of the world, specifically in developing countries. …"
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628
Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice
منشور في 2024"…Chronic use of synthetic cannabinoids (SCs) has been associated with cognitive and behavioural deficits and an increased risk of neuropsychiatric disorders. …"
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629
An Experimental Investigation of the Effects of Dressing and Grinding Parameters on Sustainable Grinding of Inconel 738 Used for Automated Manufacturing
منشور في 2023"…In this study, for the first time, the results of changes in the parameters of the dressing process and changes in the topography of the grinding surface on the surface roughness of the Inconel 738 have been presented using single-edge and four-edge diamond dressers. …"
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630
Elemental distributions in the marine sediments off Doha, Qatar: role of urbanisation and coastal dynamics
منشور في 2024"…Decadal variability is evident in element concentrations, which are linked to the urbanisation of the capital city in the State of Qatar. …"
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631
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632
Collaborative hierarchical caching and transcoding in edge network with CE-D2D communication
منشور في 2020"…However, the high load in peak hours consumes the limited available bandwidth of existing cellular and backhaul links leading to low network performance. Hence, an elastic system model is required to maintain the high Quality of Experience (QoE) as the resource demands increase. …"
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633
Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon
منشور في 2014"…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …"
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article -
634
A new perspective on cardiovascular drift during prolonged exercise
منشور في 2021"…Cardiovascular drift has been debated for a long time. Although the exact mechanisms underlying cardiovascular drift are still unknown, two theories have been proposed. …"
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635
Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice
منشور في 2024"…<p dir="ltr">Chronic use of synthetic <u>cannabinoids</u> (SCs) has been associated with cognitive and behavioural deficits and an increased risk of neuropsychiatric disorders. …"
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636
Fanconi–Bickel Syndrome: A Review of the Mechanisms That Lead to Dysglycaemia
منشور في 2020"…Missense, nonsense, frame-shift (fs), in-frame indels, splice site, and compound heterozygous variants have all been identified in SLC2A2 gene of FBS cases. Approximately 144 FBS cases with 70 different SLC2A2 gene variants have been reported so far. …"
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637
Strengthening of thin reinforced concrete slabs with CFRP laminates
منشور في 2016"…Over the years, engineers and researchers have been working continuously to reduce the dead loads on buildings by reducing the sizes of structural elements. …"
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638
Collaborative Caching for D2D Content Sharing in 5G
منشور في 2021احصل على النص الكامل
doctoralThesis -
639
Reactions, Adsorption and Diffusion in FCC Catalysts
منشور في 2013احصل على النص الكامل
doctoralThesis -
640
Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2...
منشور في 2024"…For younger demographics (ie, those aged 0–4 years and 5–14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …"
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