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1081
Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage
Published 2018“…Increased glucose entry into glycolysis in fibroblast senescence is mainly mediated by increased hexokinase-2. SFN delayed senescence by decreasing glucose metabolism on the approach to senescence, exhibiting a caloric restriction mimetic-like activity and thereby decreased oxidative damage to cell protein and DNA. …”
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1082
Unraveling the impaired incretin effect in obesity and type 2 diabetes: Key role of hyperglycemia-induced unscheduled glycolysis and glycolytic overload
Published 2024“…Incretin effect impairment is characterized by decreased secretion of incretins from enteroendocrine cells and incretin resistance of pancreatic β-cells. …”
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1083
Genotypic and phenotypic characterization of Candida albicans Lebanese hospital isolates resistant and sensitive to caspofungin
Published 2019“…Caspofungin sensitive strains showed decreased resistance to Congo red yet increased virulence and biofilm formation. …”
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1084
LDL-C Targets in Secondary Prevention: How Low Should We Go?
Published 2019“…<h3>Abstract</h3><p dir="ltr">The benefits of lowering low-density lipoprotein cholesterol (LDL-C), mainly using high-intensity statin therapy, and its impact on decreasing the recurrence of atherosclerotic cardiovascular disease (ASCVD) in secondary prevention has been well established. …”
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1085
Frugal innovation for sustainable rural development
Published 2023“…However, certain SDGs have limited potential for frugal or other types of innovation to make significant contributions, as these goals are mainly intended to be assessed at the national level. …”
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1086
Preterm birth in low-middle income Countries
Published 2024“…Although the overall trend is decreasing, this is mainly in high-income countries (HIC). …”
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1087
The influence of different preparation methods on the erosion behavior of NiP-ZrO<sub>2</sub> nanocomposite coating
Published 2023“…The erosion mechanism is mainly fracturing of splats and ploughing action at low particle velocity due to the ductility merits of the different coatings. …”
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1088
The Gut Microbiome and Colorectal Cancer: An Integrative Review of the Underlying Mechanisms
Published 2025“…The gut microbiota, comprising mainly firmicutes and bacteroidetes, play a key role in CRC development and prevention. …”
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1089
Frugal innovation for sustainable rural development
Published 2023“…However, certain SDGs have limited potential for frugal or other types of innovation to make significant contributions, as these goals are mainly intended to be assessed at the national level. …”
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1090
Simulation of the size-composition distribution of atmospheric nanoparticles over Europe
Published 2018“…The condensation of organics led to an increase (50 %–120 %) in the N100 concentration mainly in central and northern Europe, while the N10 concentration decreased by 10 %–30 %. …”
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1091
Geomorphological changes in the coastal area of Farasan Al-Kabir Island (Saudi Arabia) since mid Holocene based on a multi-proxy approach
Published 2018“…The mid Holocene evolution of the borehole area is resulted from the detailed analysis of five sedimentary units detected along the core Matar-1, and includes three distinct stages: (a) from 5253 ± 223 y cal BP to 3138 ± 223 y cal BP, carbonate coarse-grained material consisting of coral fragments, molluscs, calcareous algae and benthic foraminifera are deposited on a shallow marine fringing reefal platform, which becomes progressively a nearshore backreef (around 3675 ± 215 y cal BP), and later (around 3138 ± 223 y cal BP) a reef ramp; (b) since 3040 ± 220 y cal BP the borehole area obtains the characteristics of a high-energy beach that receives increasing inputs of terrigenous material; (c) subsequently, a supratidal backshore setting is established influenced mostly by terrestrial processes and occasionally by marine processes, as it is indicated by the decreasing and sometimes sporadic presence of benthic foraminifera, and recently, a sedimentary veneer consisting of terrigenous, carbonate and evaporite material is formed by terrestrial, mainly wadi and aeolian, processes. © 2018 Elsevier Ltd and INQUA…”
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1092
Reducing injuries among young drivers: what kind of measures are needed?
Published 2015“…For example, communication campaigns and increased enforcement may be used simultaneously and in particular target young males. …”
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1093
Pilot scale evaluation of thin film composite membranes for reducing wastewater volumes: osmotic concentration process
Published 2023“…The membrane achieved a water flux of 10 LMH, which slightly decreased to 9.6 after 48 h of operation, mainly due to inorganic scaling. …”
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1094
Visible Light Photocatalytic Activity of Ag/WO<sub>3</sub> Nanoparticles and its Antibacterial Activity Under Ambient Light and in The Dark
Published 2022“…<p dir="ltr">Nanomaterial such as metals and metal oxide photocatalysts have emerged as important tools for removing contaminants from wastewater and as antibacterial agents to prevent infections; this is mainly due to their stability under different irradiation conditions. …”
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1095
Evaluation of high-temperature reverse osmosis for recycling boiler blowdown in industrial applications
Published 2024“…The membrane rejection decreased from 97 % at 35°C to 92 % at 60°C; due to the increase in the diffusivities of ions at higher temperatures; however, the permeate quality met the boilers feedwater specifications. …”
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1096
Measuring Critical Thinking Aptitudes of High School Students in a Private School in Dubai
Published 2022“…Critical thinking is defined as a collection of basic skills that must be mastered before moving on to more complex thinking. …”
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1097
Removal of bacterial contaminants and antibiotic resistance genes by conventional wastewater treatment processes in Saudi Arabia: Is the treated wastewater safe to reuse for agricu...
Published 2015“…A culture-based approach further revealed that Pseudomonas aeruginosa was mainly found in the influent and non-chlorinated effluent but was replaced by other Pseudomonas spp. in the chlorinated effluent. …”
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1098
Efficacy and safety of using Etelcalcetide for controlling secondary hyperparathyroidism
Published 2024“…Unfortunately, 56 % of patients do not tolerate it due to mainly gastrointestinal side effects leading to poor compliance, especially during the COVID-19 pandemic when patients had difficulties in accessing the medicine and having proper follow-up. …”
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1099
The Effect of EVA and TPU Custom Foot Orthoses on Running Economy, Running Mechanics, and Comfort
Published 2019“…Compared to shoes only, mainly EVA tended to improve RE and comfort at submaximal running speeds. …”
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1100
3D Tissue-Engineered Vascular Drug Screening Platforms: Promise and Considerations
Published 2022“…<p dir="ltr">Despite the efforts devoted to drug discovery and development, the number of new drug approvals have been decreasing. Specifically, cardiovascular developments have been showing amongst the lowest levels of approvals. …”