Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors حسب Noura Aldous (15429873)

"…Recent studies have also shown <i>RFX6</i> variants to be linked with type 2 diabetes. Despite RFX6’s known function in islet development, its specific role in diabetes pathogenesis remains unclear. …"

A survey on communication technologies and requirements for internet of electric vehicles حسب Islam Safak Bayram (18421482)

Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1 حسب Bushra Memon (4792767)

Challenges in child and adolescent health across the Arab Gulf countries—Focus on metabolic health حسب Basma Haris (12040355)

"…The combination of an increasing youth population combined with rapid modernisation, increasing per capita income and the paradigm shift towards unhealthy and affluent lifestyles has created a significant burden of non‐communicable diseases (NCDs), especially obesity and diabetes. …"

Use of Animal Models for Investigating Cardioprotective Roles of SGLT2 Inhibitors حسب Najlaa A. Al Thani (17788493)

"…<p dir="ltr">Sodium-glucose co-transporter 2 (SGLT2) inhibitors represent one type of new-generation type 2 diabetes (T2DM) drug treatment. The mechanism of action of an SGLT2 inhibitor (SGLT2i) in treating T2DM depends on lowering blood glucose levels effectively via increasing the glomerular excretion of glucose. …"

Successful use of MiniMed 780G during pregnancy حسب Khaled Ahmed Baagar (17032266)

"…<h3>Background</h3><p dir="ltr">Pregnancy in the setting of type 1 diabetes (T1D) is associated with increased morbidity and mortality. …"

DNAJB3/HSP-40 cochaperone improves insulin signaling and enhances glucose uptake in vitro through JNK repression حسب Mohamed Abu-Farha (25322)

"…Nevertheless, DNAJB3 expression pattern in diabetic subjects and its mode of action are not yet known. …"

A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country حسب Nancy Zaghloul (14147865)

"…The trend among SGLT2is suggests greater preference for empagliflozin over dapagliflozin.…"

Emerging Glycation-Based Therapeutics—Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors حسب Naila Rabbani (291722)

"…<div><p>The abnormal accumulation of methylglyoxal (MG) leading to increased glycation of protein and DNA has emerged as an important metabolic stress, dicarbonyl stress, linked to aging, and disease. …"

Alpha lipoic acid attenuates ER stress and improves glucose uptake through DNAJB3 cochaperone حسب Abdoulaye Diane (14152749)

"…A similar increase in DNAJB3 mRNA was also observed in HepG2 cells. …"

Association of Differing Qatari Genotypes with Vitamin D Metabolites حسب Youssra Dakroury (9991407)

"…This may be of specific importance in vitamin D replacement strategies with the Q2 genotype requiring less, and the other genotypes requiring more to increase 1,25(OH)2D. Whilst overall the group was vitamin D deficient, total 25(OH)D was higher in diabetes, but 1,25(OH)2D, 24,25(OH)2D, and 3epi-25(OH)D were lower in diabetes that did not affect the relationship to genotype.…"

Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal حسب Zehra Irshad (18614869)

"…<p dir="ltr">Metabolic dysfunction of endothelial cells in hyperglycemia contributes to the development of vascular complications of diabetes where increased reactive glycating agent, methylglyoxal (MG), is involved. …"

Driving and hypoglycemia حسب Stephen Beer (5480411)

"…Unfortunately most diabetes medication can cause hypoglycemia. Hypoglycemia has been associated with cardiac arrhythmia, a decreased ability to drive and driving mishap. …"

The promise of tirzepatide: A narrative review of metabolic benefits حسب Sara Sokary (17337724)

"…<p>Obesity and type 2 diabetes mellites (T2DM) are intertwined epidemics that continue to pose significant challenges to global public health. …"

PDX1⁻/NKX6.1⁺ progenitors derived from human pluripotent stem cells as a novel source of insulin‐secreting cells حسب Bushra Memon (4792767)

"…<h3>Aim</h3><p dir="ltr">Beta cell replacement strategies are a promising alternative for diabetes treatment. Human pluripotent stem cells (hPSCs) serve as a scalable source for producing insulin-secreting cells for transplantation therapy. …"

Spatial modelling of contribution of individual level risk factors for mortality from Middle East respiratory syndrome coronavirus in the Arabian Peninsula حسب Oyelola A. Adegboye (4287826)

Sense and Learn: Recent Advances in Wearable Sensing and Machine Learning for Blood Glucose Monitoring and Trend-Detection حسب Ahmad Yaser Alhaddad (7017434)

"…There is an increasing demand for non-invasive blood glucose monitoring and trends detection amongst people with diabetes and healthy individuals, especially athletes. …"

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes حسب Shadi Nejat (19457212)

"…<p dir="ltr">Several pathways and/or genes have been shown to be dysregulated in obesity-induced insulin resistance (IR) and type 2 diabetes (T2D). We previously showed, for the first time, impaired expression of DNAJB3 mRNA and protein in subjects with obesity, which was concomitant with increased metabolic stress. …"

DNAJB3 attenuates ER stress through direct interaction with AKT حسب Zeyaul Islam (5867387)

"…<p dir="ltr">Metabolic stress involved in several dysregulation disorders such as type 2 diabetes mellitus (T2DM) results in down regulation of several heat shock proteins (HSPs) including DNAJB3. …"

Association of single nucleotide polymorphisms with dyslipidemia and risk of metabolic disorders in the State of Qatar حسب Dalal Al‐Sharshani (19479814)

"…<h3>Background</h3><p dir="ltr">Dyslipidemia is recognized as one of the risk factors of cardiovascular diseases (CVDs), type 2 diabetes mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD).…"