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Glycemic outcomes of Advanced Hybrid Closed Loop system in children and adolescents with Type 1 Diabetes, previously treated with Multiple Daily Injections (MiniMed 780G system in...
منشور في 2022"…<h3>Background</h3><p dir="ltr">The objective of this study was to evaluate the glycemic outcomes in children and adolescents with Type 1 Diabetes (T1D) previously treated with Multiple Daily Injections (MDI) using a structured initiation protocol for the Advanced Hybrid Closed Loop (AHCL) Minimed 780G insulin pump system. …"
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143
Differential changes in cyclic adenosine 3′-5′ monophosphate (cAMP) effectors and major Ca2+ handling proteins during diabetic cardiomyopathy
منشور في 2023"…Early upregulation of Epac1 transcripts was noted in diabetic hearts at Week 4, followed by increases in Epac2 mRNA, but not protein levels, at Week 12. …"
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144
A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
منشور في 2015"…In the presence of arachidonic acid, additional eicosanoids generated by 12/15-LOX, including 12- and 11-HETEs, were significantly increased. Fluorescein angiography and retinal albumin leakage showed a significant decrease in retinal hyperpermeability in streptozotocin-induced diabetic mice lacking 12/15-LOX compared with diabetic WT mice. …"
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145
10-Day structured initiation protocol from multiple daily injection to hybrid closed-loop system in children and adolescents with type 1 diabetes
منشور في 2020"…Time in range (70–180 mg/dL) increased from 46.9 ± 18.5% at baseline to 75.6 ± 6.9% in Auto Mode (p < 0.001). …"
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146
A Comparative Study of Safety Outcomes of Sodium Glucose Cotransporter-2 Inhibitors and Loop Diuretics Among Diabetic Patients Using Real-world Data
منشور في 2022"…In conclusion, the long-term concurrent use of SGLT2 inhibitors and loop diuretics increases the risk of volume depletion, warranting frequent monitoring.…"
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147
The impact of metformin therapy for gestational diabetes on fetal growth in women with risk factors for fetal growth restriction- a registry-based study from Qatar
منشور في 2023"…<h3>Background</h3> <p>Gestational diabetes mellitus (GDM) has been the most prevalent medical condition in pregnancy, often managed by a multidisciplinary team. …"
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148
Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample
منشور في 2020"…The prevalence of DM increased from 40.4 to 46.5% in patients hospitalized for HF. …"
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149
Diagnosing type 2 diabetes using Hemoglobin A1c: a systematic review and meta-analysis of the diagnostic cutpoint based on microvascular complications
منشور في 2020"…</p><h3>Conclusions</h3><p dir="ltr">The prevalence of nephropathy and moderate retinopathy was increased in subjects with HbA1c values ≥ 6.5% confirming the high specificity of this value for diagnosing T2DM; however, at HbA1c < 6.5% retinopathy increased at age > 55 years and, most strikingly, in African-Americans, suggesting there may be excess microvascular complication prevalence (particularly nephropathy) in individuals below the diabetes diagnostic threshold.…"
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150
Differences in protein expression, at the basal state and at 2 h of insulin infusion, in muscle biopsies from healthy Arab men with high or low insulin sensitivity measured by hype...
منشور في 2023"…Among the 924 proteins detected in both groups, three were suppressed and three were increased significantly in the LIS subjects compared with the HIS subjects. …"
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151
Elucidating the Probiotic Potential of <i>Lactobacillus</i> and <i>Bifidobacterium</i> Species in Modulating Glucose Metabolism and Inflammation in Gestational Diabetes Mellitus: A...
منشور في 2025"…<p dir="ltr">Gestational diabetes mellitus (GDM) affects 14% of pregnancies globally, contributing to gut microbial dysbiosis, inflammation, and insulin resistance. …"
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152
Type 2 Diabetes Mellitus Automated Risk Detection Based on UAE National Health Survey Data: A Framework for the Construction and Optimization of Binary Classification Machine Learn...
منشور في 2020"…This research motivated by the unprecedented increase in diabetes and specifically Type 2 Diabetes Miletus (T2DM), proposes two significant contributions. …"
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153
Uhrf1 regulates adipogenesis through GPNMB mediated TGFBeta axis
منشور في 2023"…<p><strong>Poster by Muneera Vakayil (Weill Cornell Medicine - Qatar, Hamad Bin Khalifa University), Aisha Madani (Weill Cornell Medicine - Qatar), Yasser Majeed (Weill Cornell Medicine - Qatar), and Nayef Mazloum (Weill Cornell Medicine - Qatar)</strong></p> <p>Background: The increased prevalence of obesity has led to a concomitant increase in the incidence of type 2 diabetes (T2D). …"
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154
Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
منشور في 2022"…Agonists of the glucagon-like peptide-1 receptor (GLP-1R), currently approved to treat type 2 diabetes, hold promise to improve steatosis and even steatohepatitis. …"
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155
Postprandial Insulin and Triglyceride Concentrations Are Suppressed in Response to Breaking Up Prolonged Sitting in Qatari Females
منشور في 2019"…<h3>Background</h3><p dir="ltr">Cultural, environmental and logistical factors challenge the Qatari population, particularly females, to engage in physical activity, and there is a high prevalence of diabetes in this population. Sedentary behavior is associated with increased cardiometabolic disease risk and early mortality and breaking up sitting can attenuate postprandial cardiometabolic risk markers. …"
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156
The protective effects of conditioned media from human mesenchymal stem cells against Methylglyoxal-mediated injury of cultured endothelial cells
منشور في 2023"…<p><strong>Poster by Maram Hasan and Abdelali Agouni (Qatar University)</strong></p> <p>Background: Diabetes is highly prevalent worldwide and is associated with several complications that predispose to a high risk of mortality. …"
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157
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Maternal and Neonatal Outcomes Post Bariatric Surgery: A Population-Based Study
منشور في 2023"…On the other hand, obesity significantly increased the risk of gestational diabetes, cesarean deliveries, and labor induction in comparison to the other groups.…"
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159
Long Term HbA1c Prediction Using Multi-Stage CGM Data Analysis
منشور في 2021"…<p dir="ltr">The glycated hemoglobin (HbA1c) is regarded as an essential biomarker for diabetes management. Having an elevated HbA1c level significantly increases the risk of developing diabetes-related health complications. …"
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160
The effects of Ramadan fasting on clinical and biochemical markers among hemodialysis patients: A prospective cohort study
منشور في 2019"…Diabetes was independently associated with increased IDWG by 0.48 kg (0.25, 0.72). …"