Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy... by Hmwe Hmwe, Kyu

“…The most pronounced decline was in children younger than 5 years, with a 79·2% (72·4–84·6) decrease in diarrhoeal deaths. Global YLLs also decreased substantially, from 186 million (147–221) in 1990 to 51·4 million (39·9–65·9) in 2021. …”
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Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer by Sampath, Lakshmi

“…Results: (DTPA)n-trastuzumab-(IRDye800)m showed significantly greater binding to SKBr3 cells than to MDA-MB-231 cells. …”
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The role of IT governance in enhancing the competitiveness of for-profit private schools' business by Jasim, Alaa H

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Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis by Meritxell Espino‐Guarch (22565774)

“…Further, chronic Gln accumulation and decreased proteolysis were found to induce the early onset of an age‐related muscle phenotype.…”

Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE by SHAREEF, SUNDUS LUAY

“…The variation along the short direction of the urban block has a greater positive effect and the saving in cooling energy consumption reaches 4.6 %. …”
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Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 by Joan B Soriano (6458528)

“…Death rates due to interstitial lung disease and pulmonary sarcoidosis were greater than those due to pneumoconiosis in all super-regions. …”

Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases by Glazer, Evan

“…We hypothesized that PET uptake levels were artificially decreased after chemotherapy. That is, lesions that appeared to be nonmalignant were actually viable malignant lesions.…”
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Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership by JASIM, ARIF FADHEL AHMED

“…The highest level of leaders makes fewer conceptual errors, and these errors increase as the levels decrease. Furthermore, just as there are essential conceptual skills to lead change, there are also misconceptions. …”
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Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 by Letourneau, Ian D

“…Although the global age-standardised incidence rate of appendicitis has steadily decreased between 1990 and 2021, almost half of GBD regions saw an increase of greater than 10% in their age-standardised incidence rates. …”
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Global, regional, and national prevalence of adult overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021 by Marie, Ng

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Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 by Natalia V, Bhattacharjee

“…Additionally, the distribution of livebirths across the globe is shifting, with a greater proportion occurring in the lowest-income countries. …”
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Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease St... by Jessica A, Kerr

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Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 by Stein Emil, Vollset

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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... by Michael, Brauer

“…For younger demographics (ie, those aged 0–4 years and 5–14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …”
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants by Bin, Zhou

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Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Stud... by Robert C Reiner (5147636)

“…Findings The greatest declines in diarrhoeal mortality were seen in south and southeast Asia and South America, where 54·0% (95% uncertainty interval [UI] 38·1–65·8), 17·4% (7·7–28·4), and 59·5% (34·2–86·9) of units, respectively, recorded decreases in deaths from diarrhoea greater than 10%. …”

Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019 by Hmwe Hmwe Kyu (8674014)

“…During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). …”

Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro by Najem, Sonia A.

“…Objective: In this study, we evaluated the effect of Suberoylanilide Hydroxamic Acid (SAHA), a panhistone deacetylase inhibitor, and Decitabine (DAC), a DNA methyltransferase inhibitor, either alone or in combination, on Caco-2 human colon cancer cell line in vitro. Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …”
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NMR Study of the Interaction of Trinitrobenzene with High-Spin Tetraarylporphinato-Iron(II1) Halides by Kabbani, Ahmad T.

“…The averaged TNB shifts and line-widths are indicative of 1:1 complexes whose stability is decreased by more electron-withdrawing axial halides or phenyl substituents, consistent with the porphyrin acting as a π donor in the adduct. …”
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The effects of a change in the point system on immigration by Chemin, Matthieu

“…In parallel, points for a subjective assessment of “adaptability” were decreased. In line with the initial objective, we find more French-speaking immigrants with bachelor’s degrees, and no worsening in labor market outcomes after the reform. …”
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