A Comparative Study of Safety Outcomes of Sodium Glucose Cotransporter-2 Inhibitors and Loop Diuretics Among Diabetic Patients Using Real-world Data by Alaa Rahhal (14150403)

“…In conclusion, the long-term concurrent use of SGLT2 inhibitors and loop diuretics increases the risk of volume depletion, warranting frequent monitoring.…”

The impact of metformin therapy for gestational diabetes on fetal growth in women with risk factors for fetal growth restriction- a registry-based study from Qatar by Komal Rafique (17075074)

“…<h3>Background</h3> <p>Gestational diabetes mellitus (GDM) has been the most prevalent medical condition in pregnancy, often managed by a multidisciplinary team. …”

Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample by Menatalla Mekhaimar (14103708)

“…The prevalence of DM increased from 40.4 to 46.5% in patients hospitalized for HF. …”

Diagnosing type 2 diabetes using Hemoglobin A1c: a systematic review and meta-analysis of the diagnostic cutpoint based on microvascular complications by Alexandra E. Butler (6189536)

“…</p><h3>Conclusions</h3><p dir="ltr">The prevalence of nephropathy and moderate retinopathy was increased in subjects with HbA1c values ≥ 6.5% confirming the high specificity of this value for diagnosing T2DM; however, at HbA1c < 6.5% retinopathy increased at age > 55 years and, most strikingly, in African-Americans, suggesting there may be excess microvascular complication prevalence (particularly nephropathy) in individuals below the diabetes diagnostic threshold.…”

Differences in protein expression, at the basal state and at 2 h of insulin infusion, in muscle biopsies from healthy Arab men with high or low insulin sensitivity measured by hype... by Ilham Bettahi (363910)

“…Among the 924 proteins detected in both groups, three were suppressed and three were increased significantly in the LIS subjects compared with the HIS subjects. …”

Elucidating the Probiotic Potential of <i>Lactobacillus</i> and <i>Bifidobacterium</i> Species in Modulating Glucose Metabolism and Inflammation in Gestational Diabetes Mellitus: A... by Sidra A Uzair (23124226)

“…<p dir="ltr">Gestational diabetes mellitus (GDM) affects 14% of pregnancies globally, contributing to gut microbial dysbiosis, inflammation, and insulin resistance. …”

Type 2 Diabetes Mellitus Automated Risk Detection Based on UAE National Health Survey Data: A Framework for the Construction and Optimization of Binary Classification Machine Learn... by Mohamed, AlShuweihi

“…This research motivated by the unprecedented increase in diabetes and specifically Type 2 Diabetes Miletus (T2DM), proposes two significant contributions. …”
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Uhrf1 regulates adipogenesis through GPNMB mediated TGFBeta axis by Muneera Vakayil (12037693)

“…<p><strong>Poster by Muneera Vakayil (Weill Cornell Medicine - Qatar, Hamad Bin Khalifa University), Aisha Madani (Weill Cornell Medicine - Qatar), Yasser Majeed (Weill Cornell Medicine - Qatar), and Nayef Mazloum (Weill Cornell Medicine - Qatar)</strong></p> <p>Background: The increased prevalence of obesity has led to a concomitant increase in the incidence of type 2 diabetes (T2D). …”

Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway by Olfa Khalifa (10914452)

“…Agonists of the glucagon-like peptide-1 receptor (GLP-1R), currently approved to treat type 2 diabetes, hold promise to improve steatosis and even steatohepatitis. …”

Postprandial Insulin and Triglyceride Concentrations Are Suppressed in Response to Breaking Up Prolonged Sitting in Qatari Females by Bryna C. R. Chrismas (6820142)

“…<h3>Background</h3><p dir="ltr">Cultural, environmental and logistical factors challenge the Qatari population, particularly females, to engage in physical activity, and there is a high prevalence of diabetes in this population. Sedentary behavior is associated with increased cardiometabolic disease risk and early mortality and breaking up sitting can attenuate postprandial cardiometabolic risk markers. …”

The protective effects of conditioned media from human mesenchymal stem cells against Methylglyoxal-mediated injury of cultured endothelial cells by Maram Hasan (6672440)

“…<p><strong>Poster by Maram Hasan and Abdelali Agouni (Qatar University)</strong></p> <p>Background: Diabetes is highly prevalent worldwide and is associated with several complications that predispose to a high risk of mortality. …”

Heat Shock-Related Protein Responses and Inflammatory Protein Changes Are Associated with Mild Prolonged Hypoglycemia by Abu Saleh Md Moin (6189512)

Maternal and Neonatal Outcomes Post Bariatric Surgery: A Population-Based Study by Nader I. Al-Dewik (17039794)

“…On the other hand, obesity significantly increased the risk of gestational diabetes, cesarean deliveries, and labor induction in comparison to the other groups.…”

Long Term HbA1c Prediction Using Multi-Stage CGM Data Analysis by Md Shafiqul Islam (7010348)

“…<p dir="ltr">The glycated hemoglobin (HbA1c) is regarded as an essential biomarker for diabetes management. Having an elevated HbA1c level significantly increases the risk of developing diabetes-related health complications. …”

The effects of Ramadan fasting on clinical and biochemical markers among hemodialysis patients: A prospective cohort study by Emad Khazneh (4901830)

“…Diabetes was independently associated with increased IDWG by 0.48 kg (0.25, 0.72). …”

NKX6.1 transcription factor: a crucial regulator of pancreatic β cell development, identity, and proliferation by Idil I. Aigha (14913774)

“…<p dir="ltr">Understanding the biology underlying the mechanisms and pathways regulating pancreatic β cell development is necessary to understand the pathology of diabetes mellitus (DM), which is characterized by the progressive reduction in insulin-producing β cell mass. …”

Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose by Roberta Giordo (299595)

“…Endothelial-to-mesenchymal-transition (EndMT) appears to play a role in diabetes-associated fibrotic conditions. Here, we investigate whether EndMT is implicated in the diabetic retinopathy fibrotic process and evaluate the possibility that resveratrol could counteract EndMT by inhibiting high glucose (HG)-induced increases in ROS. …”

DUSP1 Is a Potential Marker of Chronic Inflammation in Arabs with Cardiovascular Diseases by Abdelkrim Khadir (437074)

“…Multivariate logistic regression analysis showed that DUSP1 and hsCRP are independently associated with CVD in the studied population, as reflected by 2-fold and 1.5-fold increased risks with increased levels of DUSP1 and hsCRP, respectively. …”

12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase by Amira Othman (380131)

“…Treatment of REC with HETE also increased ROS generation and expression of NOX2 and pVEGF-R2 and decreased pSHP1 expression. …”

Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors by Noura Aldous (15429873)

“…Recent studies have also shown <i>RFX6</i> variants to be linked with type 2 diabetes. Despite RFX6’s known function in islet development, its specific role in diabetes pathogenesis remains unclear. …”