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661
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662
Chemotherapy prior to Hepatic Resection for Colorectal Liver Metastases: Helpful until Harmful?
منشور في 2009"…Bevacizumab can be used safely when discontinued >5 weeks before liver resection. Importantly, bevacizumab decreases the incidence and severity of sinusoidal injury with oxaliplatin therapy. …"
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663
Investigating the Quality Combined Effect of Root Cause Analysis (RCA) in Quality Management in Manufacturing Firms
منشور في 2024"…Implementing a 6KV surge protector for higher-wattage lights significantly reduced defect rates by 0.5%. This improvement led to decreased warranty claims, cost reductions, and enhanced product longevity, ultimately reinforcing the company's commitment to delivering high-quality products that exceed the customer's expectations. …"
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664
Effects of exendin-4 and selenium on the expression of GLP-1R, IRS-1, and preproinsulin in the pancreas of diabetic rats
منشور في 2017"…Diabetic rats were injected intraperitoneally with 0.03 μg exendin-4/kg body weight/daily or treated with 5 ppm selenium in drinking water for a period of 4 weeks. …"
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665
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666
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
منشور في 2025"…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…"
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667
Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making
منشور في 2019"…In contrary, for every one unit increase in concern scores, the odds of enrollment decreased among study participants by 0.98 [0.97–0.99], adj.P = 0.017. …"
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668
Rapid mercury removal using living indigenous microalgal communities for water treatment applications
منشور في 2025"…Kinetic studies showed superior correlation with the pseudo-second-order model (R<sup>2</sup> > 0.996), with rate constants decreasing systematically from 767.5 to 216.0 g/mg·min as concentration increased, suggesting secondary chemical interactions may also contribute to the overall mechanism. …"
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669
Comprehensive thermoeconomic, exergoeconomic, and optimization analyses of direct oxy‐combustion supercritical CO<sub>2</sub> intercooled and reheated cycles under design and off‐d...
منشور في 2022"…The ICC has the minimum levelized cost of electricity compared to the other cycles with 5.93 ¢/kWh at design conditions (dry‐cooling), 5.65 ¢/kWh at optimized conditions (wet‐cooling), and 7.2 ¢/kWh at minimum PD (21 MW). …"
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670
Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
منشور في 2025"…Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …"
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671
Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
منشور في 2023"…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …"
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672
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673
Advanced direct air capture of CO<sub>2</sub> using air conditioning systems: a life cycle assessment
منشور في 2025"…(ozone depletion), 8.889 × 10<sup>−5</sup> kg PM2.5 eq. (particulate matter formation), and 2.051 × 10<sup>−3</sup> m<sup>3</sup> (freshwater consumption). …"
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674
The promise of tirzepatide: A narrative review of metabolic benefits
منشور في 2025"…Tirzepatide administration for 72 weeks elicited significant weight reduction ranging from 5 % to 20.9 % across different trials in a dose-dependent manner. …"
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675
Cost-Benefit Analysis of Antimicrobial Stewardship Program in the Adult General Medicine Setting in Qatar
منشور في 2024"…</p><h3> Results</h3><p dir="ltr">The operational costs of the program decreased with maturity by cost savings of QAR125 per 100-patient beds per year. …"
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676
Deep Learning for Dynamic Wildlife Monitoring: A Real-Time Approach
منشور في 2025"…The parameters of the fine-tuned YOLOv11 decreased by 30% relative to the previous version, resulting in a very small model size of 5.5 MB and reduced processing time. …"
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677
Chromogranin A‐positive hormone‐negative endocrine cells in pancreas in human pregnancy
منشور في 2023"…</p> <h2>Results</h2> <p>The frequency of clustered β-cells was increased in pregnant compared to non-pregnant subjects (46.6 ± 5.0 vs. 31.8 ± 5.0% clustered β-cells of total clustered endocrine cells, pregnant vs. non-pregnant, <em>p</em> < .05). …"
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678
Biodegradable polysaccharide grafted polyacrylamide inhibitor for corrosion in CO<sub>2</sub>- saturated saline solution
منشور في 2023"…Lastly, potentiostatic testing of steel with AGGPAM at an applied potential of 50 mV illustrated surface protection and decreased current over a prolonged time. …"
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679
The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study
منشور في 2022"…We observed an increase in TT of 15.5 nmol/L (<i>p</i> < 0.0001), a reduction in SHBG of 10.5 nmol/L (<i>p</i> < 0.0001) and an increase in calculated free T of 383.04 pmol/L (<i>p</i> < 0.0001) over the study period. …"
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680
Chiropractic manipulations gone wrong
منشور في 2016"…Blood accumulates between the layers of the artery’s wall, obstructing blood flow and potentially forming clots. This, in turn, decreases the blood supply to the brain, causing stroke. …"