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621
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622
Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue
منشور في 2014"…Impairment of heat shock response (HSR) has been already linked to diabetes and insulin resistance as reflected by decrease in heat shock proteins (HSPs) expression. …"
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623
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624
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625
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626
The Activation Kinetics and Crosstalk of RhoGTPases
منشور في 2020"…Biosensors are two chromophores linked to 2 entities, joined together by a linker which determines their juxtaposition relative to each other, and thus the amount of energy transfer. …"
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masterThesis -
627
Structural and Biophysical Characterization of Stable Alpha-Synuclein Oligomers
منشور في 2022"…It has been reported that the brains of deceased patients with PD contain high levels of protein oligomers that are cross-linked to these aldehydes. Increasing evidence also suggests that prefibrillar oligomeric species are more toxic than the mature amyloid fibrils. …"
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628
Genomic and pleiotropic analyses of resting QT interval identifies novel loci and overlap with atrial electrical disorders
منشور في 2021"…These findings provide novel insights into how abnormal myocardial repolarization and increased cardiovascular mortality may be linked.</p><p> </p></div><h2>Other Information</h2> <p> Published in: Human Molecular Genetics<br> License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1093/hmg/ddab197" target="_blank">https://dx.doi.org/10.1093/hmg/ddab197</a></p>…"
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629
Assessment of Qatar’s road network under sea-level-rise scenarios using traffic simulation and graph theory
منشور في 2025"…High-resolution maps derived from IPCC-AR6 and NOAA projections show that without adaptation measures, SLR may affect approximately 3–11% of land and 2–17% of roads in Qatar, potentially increasing trip durations up to 15 times. Importantly, the estimated impacts are indicative trends rather than definitive outcomes linked to specific emissions scenarios. …"
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630
Metformin Induces Different Responses in Clear Cell Renal Cell Carcinoma Caki Cell Lines
منشور في 2019"…Persistently activated HIF-1α is associated with increased cell proliferation, angiogenesis, and epithelial–mesenchymal transition (EMT), consequently leading to ccRCC progression and metastasis to other organs. …"
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631
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632
Across the Spectrum In-Depth Review AI-Based Models for Phishing Detection
منشور في 2024"…<p dir="ltr">Advancement of the Internet has increased security risks associated with data protection and online shopping. …"
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633
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634
Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
منشور في 2024"…Furthermore, RFX6 deficiency resulted in the formation of smaller islet organoids due to increased cellular apoptosis, linked to reduced catalase expression, implying a protective role for RFX6. …"
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635
Governing desalination, managing the brine: A review and systematization of regulatory and socio-technical issues
منشور في 2023"…<p>Desalination has become an attractive option for addressing water needs or solving problems of increasing water scarcity and short-term supply interruptions. …"
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636
The Obesity Paradox in Cancer, Tumor Immunology, and Immunotherapy: Potential Therapeutic Implications in Triple Negative Breast Cancer
منشور في 2019"…For instance, obesity has emerged as a risk factor for a dampened anti-tumor immune response and increased risk of immunotherapy-induced immune-related adverse events (irAEs) but has also been linked to improved outcomes with checkpoint blockade. …"
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637
Photobiomodulation: A Systematic Review of the Oncologic Safety of Low-Level Light Therapy for Aesthetic Skin Rejuvenation
منشور في 2023"…<p dir="ltr">Photobiomodulation (PBM) therapy is an increasingly popular modality for aesthetic skin rejuvenation. …"
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638
Diversity of hydrocarbon-degrading bacteria isolated from the rhizosphere of mangrove forests in two coastal regions of Qatar
منشور في 2025"…These variations were reflected in variations in growth, biosurfactant activity, and hydrocarbon degradation capabilities, with differing protein profiles linked to varying hydrocarbon removal efficiencies. …"
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639
Early‐Life Sugar Consumption Affects the Microbiome in Juvenile Mice
منشور في 2023"…<p></p><div> <h3> Scope</h3> <p>The composition of the gut microbiota is influenced by the dietary nutrient. Sugar has been linked with many metabolic health disorders such as heart disease, metabolic syndrome, and immune disorders. …"
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640