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101
Increased cellular protein modification by methylglyoxal activates endoplasmic reticulum-based sensors of the unfolded protein response
Published 2024“…Human aortal endothelial cells and HMEC-1 microvascular endothelial cells were incubated in low and high glucose concentration to model blood glucose control, with increase or decrease of MG by silencing or increasing expression of glyoxalase 1 (Glo1), which metabolizes MG. …”
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102
Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-...
Published 2025“…While some real-world studies have reported a decrease in VOCs and hospitalizations, the results are inconsistent and not conclusive. …”
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103
Fourier Transform Infrared Imaging—A Novel Approach to Monitor Bio Molecular Changes in Subacute Mild Traumatic Brain Injury
Published 2021“…According to FTIR imaging results, total protein and lipid content significantly decreased in both Co and CC regions in mTBI group compared to the control. …”
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104
BRET-based biosensors for SARS-CoV-2 oligonucleotide detection
Published 2024“…Following the assembly of the BioODs, we determined their kinetics response, affinity for variant-specific oligonucleotides, and specificity, and found them to be rapid and highly specific. Furthermore, the decrease in BRET efficiency of the BioODs in the presence of viral oligonucleotides can be detected as a change in color in cell phone camera images. …”
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105
Alterations in Beta Cell Identity in Type 1 and Type 2 Diabetes
Published 2019“…Moreover, altered identity of mature β cells in diabetes also involves transdifferentiation of β cells into other islet hormone producing cells. For example, overexpression of α cell specific transcription factor Arx or ablation of Pdx1 resulted in an increase of α cell numbers and a decrease in β cell numbers in rodents. …”
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106
A combined experimental and computational study of the effect of electron irradiation on the transport properties of aromatic and aliphatic molecular self-assemblies
Published 2022“…This structural modification also results in a significant decrease of the current. These findings can be useful in understanding the processes during the electron irradiation of molecular SAMs.…”
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107
Essays on Renewable Energy Dynamics & Co₂ Emissions: Insights From Selected OIC Countries and World Nations
Published 2025“…Based on the estimation results, the study gives important policy recommendation in the direction of decreasing greenhouse gas emissions for world countries.…”
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108
DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation
Published 2019“…Using JNK1- and IKKβ-dependent luciferase reporters, we show a marked decrease in luciferase activity by DNAJB3 in response to PMA and TNF-α that was consistent with a decrease in the translocation of p65/NF-κB to the nucleus in response to LPS. …”
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109
Correlating the rheological and magneto-optical properties of cobalt substituted magnetite ferrofluids (Co<sub>x</sub>Fe<sub>1−x</sub>Fe<sub>2</sub>O<sub>4</sub>) with theoretical...
Published 2023“…The optical measurement results demonstrate shift in band edge positions to blue region with decrease in particle size because of the quantum confinement effect. …”
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110
Effects of organic enrichment on macrofauna community structure: an experimental approach
Published 2013“…AMBI and M-AMBI indices were calculated and a decrease of ecological status was observed in treatment 3x.…”
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111
Application of Zn-ferrite towards thermochemical utilization of carbon dioxide: A thermodynamic investigation
Published 2021“…However, as the gas-to-gas heat recovery effectiveness increases to 0.9, this difference decreases to 11.8 kW. Because of this, the reduction in the solar-to-fuel energy conversion efficiency also drops to 0.6%. …”
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112
The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global...
Published 2020“…Oesophageal cancer caused 9·78 million (9·53–10·03) DALYs, with an age-standardised rate of 120 (117–123) per 100 000 population. Between 1990 and 2017, age-standardised incidence decreased by 22·0% (18·6–25·2), mortality decreased by 29·0% (25·8–32·0), and DALYs decreased by 33·4% (30·4–36·1) globally. …”
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113
The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe
Published 2023“…This research indicates a positive correlation between living alone and loneliness, with a greater effect on males, and identifies loneliness as an independent factor decreasing QoL. …”
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114
Mechanisms behind the immediate effects of Roux-en-Y gastric bypass surgery on type 2 diabetes
Published 2013“…I.e., the largest possible decrease in glucose predicted by the model is smaller than reported decreases, and the model predicts no decrease whatsoever in glucose ×insulin, in contrast to large observed decreases in homeostatic model assessment insulin resistance (HOMA-IR). …”
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115
Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension
Published 2023“…Hypoglycemia were more prevalent among neonates of non-hypertensive mothers. On the other hand, neonates of hypertensive mothers administered with methyldopa showed a significant decrease of initial blood glucose reading.…”
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116
Effects of polyphenol‐rich traditional herbal teas on obesity and oxidative stress in rats fed a high‐fat–sugar diet
Published 2023“…Higher doses of <i>Hibiscus rosa-sinensis</i> significantly decreased the levels of AST, ALT, AP, and SC in comparison with the HFSDC group. …”
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117
Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials
Published 2023“…</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …”
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118
The burden of unintentional drowning: global, regional and national estimates of mortality from the Global Burden of Disease 2017 Study
Published 2020“…Global age-standardised mortality rates decreased 57.4%, from 9.3 (8.5 to 10.0) in 1990 to 4.0 (3.8 to 4.1) per 100 000 per annum in 2017. …”
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119
A control algorithm to increase the efficient operation of wind energy conversion systems under extreme wind conditions
Published 2022“…<p dir="ltr">This paper aims to increase the power production of gearless permanent magnet synchronous generator (PMSG) based wind energy conversion systems (WECS) in strong (greater than 25 m/s) wind speed regions. In general, most wind turbines cut off when wind speed is over the cut-out rate; as a result, the power generation of the wind farm decreases. …”
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120
Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue
Published 2014“…Impairment of heat shock response (HSR) has been already linked to diabetes and insulin resistance as reflected by decrease in heat shock proteins (HSPs) expression. …”