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Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion
Published 2016“…However, astrocytoma cells that were treated with LeTx showed a significant decrease in cell motility as seen by wound healing as well as random 2D motility in serum. …”
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The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis
Published 2013“…We indeed determined that the PF treatment led to a decrease in p-ERK as compared to total ERK levels, whereas the level of phosphorylated Akt was not affected. …”
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Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy
Published 2020“…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …”
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Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
Published 2022“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”
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Leftover spaces for the mitigation of urban overheating in municipal Beirut
Published 2018“…In some cases, the introduction of trees leads to an increase of the air temperature near the ground because they became an obstacle of the natural ventilation. …”
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Daytime Variation of Urban Heat Islands: The Case Study of Doha, Qatar
Published 2016“…<p>Recent evidence suggests that urban forms and materials can help to mediate temporal variation of microclimates and that landscape modifications can potentially reduce temperatures and increase accessibility to outdoor environments. To understand the relationship between urban form and temperature moderation, we examined the spatial and temporal variation of air temperature throughout one desert city—Doha, Qatar—by conducting vehicle traverses using highly resolved temperature and GPS data logs to determine spatial differences in summertime air temperatures. …”
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The effect of building height diversity on outdoor microclimate conditions in hot climate. A case study of Dubai-UAE
Published 2020“…Previous studies focused on traditional methods of increasing the shading effect, e.g. buildings' height/canyon width (H/W) ratio. …”
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Gaining or Losing Team Ball Possession: The Dynamics of Momentum Perception and Strategic Choice in Football Coaches
Published 2019“…Nonetheless, both variables displayed asymmetrical effects, in the sense that: (1) the strength of positive PM appeared to be easier to decrease than to increase; and (2) the greater the positive PM (or the negative PM), the lesser (or the greater) the coaches’ tendency to make a change in the organization of their teams. …”
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Effect of consanguinity on birth weight for gestational age in a developing country
Published 2007“…No significant difference was observed in the decrease in birth weight between the first- and second-cousin marriages. …”
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Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways
Published 2017“…The SW1116 colon cancer cell line was treated with HC (1, 5, 10 and 25 μg/ml) and cell viability was evaluated with WST 1 assay kit. …”
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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
Published 2016“…Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…”
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An innovative twin-technology solar system design for electricity production
Published 2024“…While the external tower creates a downdraft wind by spraying water at the hot ambient air at the top of the tower. The hot air instantly absorbs the water and descends the tower to interact with the turbines at the bottom to produce electricity. …”
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A comprehensive design and rating study of evaporative coolers and condensers. Part II. Sensitivity analysis
Published 2020“…For evaporative condenser design, it was seen that, for a 53% increase in the inlet relative humidity, the normalized sensitivity of the surface area increased 1.8 times in value and, for a 15 8C increase in the condenser temperature, the sensitivity increased by 3.5 times. …”
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Exploring urban growth–climate change–flood risk nexus in fast growing cities
Published 2022“…In addition, Doha witnessed various climatic changes with a notable increase in air temperature (+ 8.7%), a decrease in surface wind speed (− 19.5%), and a decrease in potential evapotranspiration losses (− 33.5%). …”
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Improving the Performance Measurement Using Overall Equipment Effectiveness (OEE) in Borouge
Published 2023“…The main issue found relating to the two extruder production lines productivity was where availability and quality show a significant decrease. …”
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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