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Metabolic profiling of pre-gestational and gestational diabetes mellitus identifies novel predictors of pre-term delivery
Published 2020“…<h3>Background</h3><p dir="ltr">Pregnant women with gestational diabetes mellitus (GDM) or type 2 diabetes mellitus (T2DM) are at increased risks of pre-term labor, hypertension and preeclampsia. …”
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102
Comprehensive analysis of circulating miRNA expression profiles in insulin resistance and type 2 diabetes in Qatari population
Published 2022“…<p dir="ltr">Insulin resistance (IR) is type 2 diabetes’ hallmark. MiRNAs regulate many target genes that makes them attractive candidates for regulating insulin production, secretion and action. …”
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103
Impact of COVID-19 related home confinement measures on the lifestyle, body weight, and perceived glycemic control of diabetics
Published 2021“…We found a significant increase in the sitting/reclining, and screen times. …”
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104
Effects of exendin-4 and selenium on the expression of GLP-1R, IRS-1, and preproinsulin in the pancreas of diabetic rats
Published 2017“…Selenium treatment of diabetic rats increased the pancreatic mRNA levels of GLP-1R, IRS-1, and preproinsulin. …”
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105
Hexokinase-2-Linked Glycolytic Overload and Unscheduled Glycolysis—Driver of Insulin Resistance and Development of Vascular Complications of Diabetes
Published 2022“…This may explain the increased glucose disposal by skeletal uptake in the fasting phase in patients with type 2 diabetes mellitus, compared to healthy controls, and the presence of insulin resistance in patients with type 1 diabetes mellitus. …”
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106
High fractional excretion of glycation adducts is associated with subsequent early decline in renal function in type 1 diabetes
Published 2020“…<div><p>Increased protein glycation, oxidation and nitration is linked to the development of diabetic nephropathy. …”
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107
The Role of Epidermal Growth Factor Receptor Family of Receptor Tyrosine Kinases in Mediating Diabetes-Induced Cardiovascular Complications
Published 2021“…It is the complications of diabetes such as cardiovascular, renal, neuronal and ocular dysfunction that lead to increased patient morbidity and mortality. …”
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108
Strong association of common variants in the IGF2BP2 gene with type 2 diabetes in Lebanese Arabs
Published 2012“…Objective Several genome-wide association studies and replication analyses have identified common variation at the insulin-like binding protein 2 (IGF2BP2) gene to be associated with type 2 diabetes (T2DM). The aim of this study was to replicate in a Lebanese Arab population identified associations of IGF2BP2 variants rs4402960 and rs1470579 with T2DM. …”
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109
Prevalence, correlates and management of hyperglycemia in diabetic non-critically Ill patients at a tertiary care center in Lebanon
Published 2019“…Episodes of hyperglycemia in hospitalized diabetic patients are associated with poor clinical outcomes and increased morbidity and mortality. …”
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110
Preventing type 2 diabetes mellitus in Qatar by reducing obesity, smoking, and physical inactivity: mathematical modeling analyses
Published 2019“…</p><h3>Results</h3><p dir="ltr">T2DM prevalence increased from 16.7% in 2016 to 24.0% in 2050 in the baseline scenario. …”
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111
Oral Spirulina Platensis Attenuates Hyperglycemia and Exhibits Antinociceptive Effect in Streptozotocin-Induced Diabetic Neuropathy Rat Model
Published 2020“…</p><h3>Results</h3><p dir="ltr">Pain scores were increased in the diabetic groups during both phases of the experiment. …”
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112
Salivary α-amylase activity is associated with cardiometabolic and inflammatory biomarkers in overweight/obese, non-diabetic Qatari women
Published 2024“…<h3>Introduction</h3><p dir="ltr">Obesity, prevalent in approximately 80% of Qatar’s adult population, increases the risk of complications like type 2 diabetes and cardiovascular diseases. …”
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113
Chromogranin A‐positive hormone‐negative endocrine cells in pancreas in human pregnancy
Published 2023“…<h2>Introduction</h2> <p>We sought to determine whether chromogranin A-positive hormone-negative (CPHN) endocrine cells are increased in the pancreas of pregnant women, offering potential evidence in support of neogenesis.…”
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114
Effects of selenium in comparison to exendin-4 on the expression of GLP-1R, IRS-1 and preproinsulin in the pancreas of diabetic rats
Published 2016“…Results obtained indicate that GLP-1R and IRS-1 levels decreased while the level of preproinsulin mRNA increased in the pancreas of diabetic untreated rats, as compared to control rats. …”
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115
Intraocular pressure trends after intravitreal injections of anti-vascular endothelial growth factor agents for diabetic macular edema
Published 2015“…Purpose: To study intraocular pressure (IOP) trends and risk factors of IOP elevation after intravitreal anti-vascular endothelial growth factor injections in diabetic macular edema. Methods: A retrospective review of 760 eyes treated with intravitreal anti-vascular endothelial growth factor injections for diabetic macular edema was performed. …”
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Physical Exercise Enhanced Heat Shock Protein 60 Expression and Attenuated Inflammation in the Adipose Tissue of Human Diabetic Obese
Published 2018“…Indeed, HSP60 expression levels in SAT were significantly increased by exercise in the diabetes group, whereas they were decreased in the non-diabetes group. …”
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Vitamin D<sub>3</sub> metabolite ratio as an indicator of vitamin D status and its association with diabetes complications
Published 2020“…Therefore, VMR was determined in a population with type 2 diabetes at high risk for vitamin D deficiency and correlated with diabetic complications.…”
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119
Insulin detemir in combination with oral antidiabetic drugs improves glycemic control in persons with type 2 diabetes in Near East countrie
Published 2017“…Conclusions Initiating insulin detemir in a clinical health care setting among Lebanese with type 2 diabetes mellitus on OADs improves glycemic control with no increase in hypoglycemia, adverse events or weight compared with baseline.…”
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120
Association of dyslipidemia, diabetes and metabolic syndrome with serum ferritin levels: a middle eastern population-based cross-sectional study
Published 2021“…Exclusively in women, the ORs for IR (HOMA-IR > 3.58) increased significantly in Q4 (OR 1.79 (1.19–2.70)) versus OR 1 in Q1 as did the ORs for diabetes (OR: 2.03 (1.15–3.57) in Q4 versus OR 1 in Q1). …”