Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy حسب Jia-Zhen Wu (6844793)

"…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). …"

Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery حسب Stephen L. Atkin (6684368)

"…<h3>Background: </h3><p dir="ltr">Early metabolic responses following bariatric surgery appear greater than expected given the initial weight loss and coincide with improvement in diabetes. …"

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications حسب Jingxuan Shan (4711089)

"…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. A decreased risk of lymph node metastasis was associated with the <b><i>MAP3K21</i></b><b> </b><b>rs1294255-C</b> allele, particularly in <b>rs1294255-GC</b> (OR = 0.47; <i>P</i> = 0.001). …"

Control of TGFβ signalling by ubiquitination independent function of E3 ubiquitin ligase TRIP12 حسب Kripa S Keyan (10644815)

"…<p dir="ltr">Transforming growth factor β (TGFβ) pathway is a master regulator of cell proliferation, differentiation, and death. …"

Evaluation of Lycopus uniflorus water extract for anti-inflammatory, anti-ulcerogenic and antioxidant activities حسب Saade, S.

"…The highest inhibition of edema development was achieved at 100mg/kg BW dose and the edema was decreased by 67% compared with diclofenac (60%) at 10mg/kg BW. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Two-stage optimisation for malachite green removal using activated date pits حسب M. Hijab (14152095)

"…<p>Water pollution, from industry and agriculture, is a major threat to water security in the light of decreasing global potable water resources. Adsorption is one potential treatment technology for the removal of different contaminants from polluted water. …"

Swimming exercise improves short‐ and long‐term memories: Time‐course changes حسب Mahmoud A. Alomari (14780446)

"…The mean total errors on RAWM during the learning phase and memory testing remained the same (p > 0.5) after 1 day of swimming exercise. …"

Crunching the numbers of food poisoning in Qatar حسب Nature Research (16552612)

"…Three-fourths of the cases in that same year were non-Qataris, with Indians, Egyptians and Pakistanis forming a large bulk of those affected. …"

Effect of Mg incorporation on the properties of PCL/Mg composites for potential tissue engineering applications حسب Sumama Nuthana Kalva (19206064)

"…However, the elastic modulus decreased by around 50% for the same composition. The thermal study revealed a significant reduction in the degradation temperature from above 400°C for pure PCL to around 300°C for PCL/Mg composite having 15% Mg. …"

Rapid mercury removal using living indigenous microalgal communities for water treatment applications حسب Amr Nasr Fekry (22521185)

"…Comprehensive isotherm analysis revealed the Dubinin-Radushkevich model provided the best fit (R² = 0.998), indicating physical adsorption as the predominant mechanism, as the calculated mean free energy (E = 5.00 kJ/mol) falls within the 1–8 kJ/mol range characteristic of physical adsorption. …"

The Effect of High Dose Isoflavone Supplementation on Serum Reverse T3 in Euthyroid Men With Type 2 Diabetes and Post-menopausal Women حسب Thozhukat Sathyapalan (704787)

"…Thyroid stimulating hormone (TSH) serum concentrations increased while free thyroxine (fT₄) concentrations decreased with 3 months of SPI compared to SP supplementation for both men and women. rT₃ correlated with TSH in both studies (<i>p</i> = 0.03) but not with either fT₃ or fT₄. fT₃ levels did not differ between the SPI and SP preparations.…"

Caloric restriction reduces trabecular bone loss during aging and improves bone marrow adipocyte endocrine function in male mice حسب Charlotte Rinne (18766966)

"…Cortical bone, however, was decreased in young mice on CR and remained reduced in aged mice, irrespective of dietary intervention. …"

Novel proteins implicated in lipid metabolism disorders حسب Nature Research (16552612)

"…</p><p>ANGPTL4 is a protein that is activated during fasting, decreasing the release of free fatty acids from circulating triglyceride-rich lipoproteins. …"

Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy... حسب Hmwe Hmwe, Kyu

"…The most pronounced decline was in children younger than 5 years, with a 79·2% (72·4–84·6) decrease in diarrhoeal deaths. Global YLLs also decreased substantially, from 186 million (147–221) in 1990 to 51·4 million (39·9–65·9) in 2021. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Risk factors for stoma outlet obstruction: systematic review and meta-analysis حسب Ali Toffaha (18111886)

"…<h3 dir="ltr">Introduction</h3><p dir="ltr">Stoma outlet obstruction (SOO) is a serious postoperative complication that can lead to significant morbidity, including prolonged hospitalization, increased healthcare costs, and reduced quality of life. …"

Association between clinical laboratory indicators and WOMAC scores in Qatar Biobank participants: The impact of testosterone and fibrinogen on pain, stiffness, and functional limi... حسب Ovelia Masoud (22282864)

"…This study explored the relationship between clinical laboratory profiles and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores for pain, stiffness, and physical functional limitation in healthy individuals in Qatar.…"

Phase state of secondary organic aerosol in chamber photo-oxidation of mixed precursors حسب Yu Wang (12152)

"…Although less important than RH and MR_org/inorg, the SOA composition plays a second-order role, with differences in the liquid-to-nonliquid transition at moderate MR_org/inorg of ∼ 1 observed between biogenic-only (anthropogenic-free) and anthropogenic-containing VOC systems. Considering the combining role of the RH and chemical composition in aerosol phase state, the BF decreased monotonically with increasing hygroscopic growth factor (GF), and the BF was ∼ 0 when GF was larger than 1.15. …"

An efficient failure-resilient mutual exclusion algorithm for distributed systems leveraging a novel zero-message overlay structure حسب Mouna Rabhi (17086969)

"…The proposed algorithm avoids node disconnection while minimally impacting the load of the logical tree nodes. In addition, for the same architecture, when both tree arity and cardinality are 4, after 250 epochs, the node load has demonstrated minimal variation and remains in close proximity to the original load. …"

Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer حسب Sampath, Lakshmi

"…Results: (DTPA)n-trastuzumab-(IRDye800)m showed significantly greater binding to SKBr3 cells than to MDA-MB-231 cells. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) حسب Azar, Daniel Fadi

احصل على النص الكامل
احصل على النص الكامل