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21
Human Recombinant Arginase I (Co)-PEG5000-Induced Arginine Depletion of Breast Cancer Cell Lines Causes Autophagy Mediated Cell Death
Published 2024“…Inhibition of autophagy decreased sensitivity to arginase-induced cytotoxicity in all cell lines, and hence reversed cell death. …”
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Acute pain management and assessment
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Comparative Effect of Sodium Butyrate and Sodium Propionate on Ovarian Cancer Migration, Invasion, and Epithelial-To-Mesenchymal Transition
Published 2025“…Methodology: The two ovarian cancer cell lines, SKOV-3 and PA-1, were treated with NaB and NaP for 24h. …”
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masterThesis -
26
Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…The use of a CRISPR-dCas9 UNISAM and KRAB system could increase or decrease SLFN11 expression significantly (up to fivefold), stably and specifically in BT-549 and T47D cancer cell lines. …”
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Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent
Published 2019“…Addition of excess L-citrulline rescued only one of three cell lines tested, indicating that the majority of cell lines are completely auxotrophic for arginine. …”
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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
Published 2017“…In this study, we examined the mechanisms of arginine auxotrophy in PC cell lines. Sensitivity to arginine depletion using HuArgI (Co)-PEG5000 was evident in all of the tested PC cell lines with IC50 values in the pM range at 72 hours following treatment. …”
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29
Daucus carota pentane/diethyl ether fraction inhibits motility and reduces invasion of cancer cells
Published 2015“…Upon treatment, a pronounced decrease in cancer cell motility was observed in the 4 cell lines. …”
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Role of intravitreal antivascular endothelial growth factor injections for choroidal neovascularization due to choroidal osteoma
Published 2014“…BCVA improved by 3.3 lines at 6 months after therapy (n = 26; P = 0.003 ), 2.8 lines (n = 20; p less than 0.001 ) at 1 year, and 3.1 lines ( n = 20; P = 0.01) at 2 years. …”
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31
The antioxidant and anticancer effects of Wild Carrot oil extract
Published 2012“…Also, DCOE demonstrated a significant increase in cell death and decrease in cell proliferation. The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …”
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The effect of daucus carota pentane-diethylether fraction on cancer cells motility and metastasis. (c2013)
Published 2013“…Upon treatment, a pronounced decrease in cancer cell motility was observed in the four cell lines used. …”
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33
Medication safety spontaneous reporting system
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
Published 2021“…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …”
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35
Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…In this study we examined the anticancer effect of Daucus carota oil extract (DCOE) fractions on the human breast adenocarcinoma cell lines MDA-MB-231 and MCF-7 and clarified the mechanism of action. …”
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Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion
Published 2016“…However, astrocytoma cells that were treated with LeTx showed a significant decrease in cell motility as seen by wound healing as well as random 2D motility in serum. …”
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The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis
Published 2013“…We indeed determined that the PF treatment led to a decrease in p-ERK as compared to total ERK levels, whereas the level of phosphorylated Akt was not affected. …”
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Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy
Published 2020“…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …”
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39
Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
Published 2022“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”
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Tabu search based circuit optimization
Published 1998“…Such a strategy leads to sizable circuit speed improvement with minimum increase in the overall circuit capacitance. Compared to earlier approaches, the presented technique produces circuits with remarkable increase in speed (greater than 20%) for very small increase in overall circuit capacitance (less than 3%)…”
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