-
161
Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing
Published 2022“…</p><h3>Results</h3><p dir="ltr">The majority of PRSs performed well; odds ratio (OR) per 1 SD increase (OR1sd) was highest for PGS000337 (OR1sd=1.81, 95% CI [1.66–1.98], <i>P</i>=3.07×10−41). …”
-
162
Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2...
Published 2024“…For younger demographics (ie, those aged 0–4 years and 5–14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …”
Get full text
Get full text
Get full text
article -
163
The Impact of Board Gender Diversity on European Firms’ Performance: The Moderating Role of Liquidity
Published 2024“…Our findings indicate that an increased representation of women on the board of directors is associated with greater independence among board members and a higher number of board members being hired. …”
-
164
Outcomes of drain versus no drain in total knee arthroplasty: a retrospective cohort study
Published 2023“…</p><h3>Conclusions</h3><p dir="ltr">This study found that patients who received a drain had longer hospital stays and greater blood loss and transfusion rates compared to those who did not. …”
-
165
The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe
Published 2023“…Europe‘s aging population is increasing, affecting various sectors, including the healthcare system, labor market, and public services. …”
Get full text
-
166
Effect of Surgical Margin Status on Survival and Site of Recurrence After Hepatic Resection for Colorectal Metastases
Published 2005“…Adverse preoperative biologic factors including tumor number greater than 3 (P = 0.01) and a preoperative CEA level greater than 200 ng/mL (P = 0.04) were associated with an increased risk of positive surgical margin. …”
Get full text
Get full text
Get full text
article -
167
MRP4
Published 2011“…Application of ISO (1nM) induced a similar increase in cAMP level in WT and MRP4 KO mice (YFP/CFP: 4.4 ± 0.15 in WT vs 4.1 ± 0.44 in KO cells), whereas cAMP signal was greater in MRP4 KO compared to WT mice after PDE inhibition by IBMX (ISO 1nM + IBMX 300µM: 8.1 ± 0.6 in WT vs 11.8 ± 0.62 in KO cells; p<0.01). …”
Get full text
Get full text
Get full text
article -
168
-
169
Integration of Smart Sensors in Buildings to achieve Energy Efficiency in Hot and Humid Climate
Published 2021“…It is also estimated that this utilization would grow to above 50% by 2030 because of the fast and consistent growth in economic activity and increase in population around the world. People tend to spend the greater part of their time in indoor spaces e.g., commercial and residential buildings. …”
Get full text
-
170
Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
Published 2024“…The share of livebirths was projected to decline between 2021 and 2100 in most of the six other super-regions—decreasing, for example, in south Asia from 24·8% (23·7–25·8) in 2021 to 16·7% (14·3–19·1) in 2050 and 7·1% (4·4–10·1) in 2100—but was forecast to increase modestly in the north Africa and Middle East and high-income super-regions. …”
Get full text
Get full text
Get full text
article -
171
Chemical, rheological, and sensory properties of wheat biscuits fortified with local buckwheat
Published 2023“…The samples with <i>F</i>. tataricum demonstrated greater amounts of fiber and ash while the samples made of soft wheat flour were rich in carbohydrates. …”
-
172
Knee Angle Affects Posterior Chain Muscle Activation During an Isometric Test Used in Soccer Players
Published 2019“…These differences (30% mean difference) were greater than the observed typical measurement error (CV% = 13.1–14.3 for the 90° and 30° test positions, respectively). …”
-
173
-
174
Location matters: spatial dynamics of tumor-infiltrating T cell subsets is prognostic in colon cancer
Published 2024“…Higher densities of stromal CD3<sup>+</sup>FoxP3<sup>+</sup> T cells showed enhanced survival outcomes, and patients exhibited superior clinical benefits when greater spatial distances were observed between CD3<sup>+</sup>CD8<sup>-</sup>FoxP3<sup>-</sup> or CD3<sup>+</sup>CD8<sup>+</sup> T cells and CD3<sup>+</sup>FoxP3<sup>+</sup> T cells.…”
-
175
Genomic architecture of autism spectrum disorder in Qatar: The BARAKA-Qatar Study
Published 2023“…Moreover, homozygous variants were found in 7 families (25.9%), with a sixfold increase in homozygous burden in consanguineous versus non-consanguineous families (13.6% and 1.8%, respectively). …”
-
176
-
177
The benefits of employees' empowerment
Published 2013“…More responsibility generates greater productivity, and commitment. Most employees were more productive when empowered by management; almost all firms recognize the importance of increased employee performance and measure it. …”
Get full text
Get full text
Get full text
article -
178
Combating political hostage‐taking
Published 1992“…Rational actor models have examined the effects of increasing punishment or the probability of apprehension on terrorists activities including hostage‐taking. …”
Get full text
Get full text
Get full text
Get full text
article -
179
-
180
The impact of scoliosis surgery on pulmonary function in spinal muscular atrophy: a systematic review
Published 2022“…Respiratory and spine-based complications were common. Given the available evidence, the following GRADE C recommendations were made: (1) surgery is most often associated with decreases in pulmonary function; (2) the impact of surgery on pulmonary function is variable, but does not improve over pre-operative baseline; (3) surgery may result in a decreased rate of decline in pulmonary function post-operatively. …”