Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response by Noura Al-Zeheimi (5177066)

“…To further identify the role of NRP-1 and its interacting molecules in correspondence with patients' response to neoadjuvant chemotherapy (NAC), we conducted a comparative study on blood and tissue samples collected from a cohort of locally advanced breast cancer patients, before and after neoadjuvant chemotherapy (NAC). From a panel of tested proteins and genes, we found that the levels of plasma NRP-1, placenta growth factor (PlGF) and immune cell expression of the transcription factor <i>SNAI1</i> before and after NAC were significantly different. …”

Positional and dimensional temporomandibular joint osseous changes in patients treated with the forsus fatigue resistant device: a non-randomized clinical trial by Ramy Abdul-Rahman Ishaq (22928974)

“…Participants were divided into a treatment and a control group. After alignment and leveling with fixed orthodontic appliances using 0.019 × 0.025-inch stainless-steel archwires, the FFRD was fitted. …”

‘The newest vital sign among pregnant women attending women wellness and research Centre in Qatar: a cross-sectional study’ by Sarah Naja (9954737)

“…In the context of pregnancy, inadequate health literacy has been linked to several adverse outcomes among pregnant women such as unplanned conception, smoking, and lack of multi-vitamin intake. Given the paucity of data, this study aimed to assess the level of health literacy and its determinants among pregnant women in the State of Qatar.…”

Epibenthic communities from offshore platforms in the Arabian Gulf are structured by platform age and depth by Felipe, Torquato

“…A step further is now required to determine whether these platform foundations should be converted to reefs after their decommissioning (i.e., Rigs to Reefs approach).…”
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Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function by Muge Sarper (3855454)

“…Conversely, knock-down of MMP-8 in N-1089 reduced adhesion and increased migration. Expression of MMP-8 WT in β6-1089 led to greater localisation of α6β4 to HD and reduced retraction fibre formation, this being reversed by MMP-8 knock-down in N-1089. …”

Prognostic effects of cardiopulmonary resuscitation (CPR) start time and the interval between CPR to extracorporeal cardiopulmonary resuscitation (ECPR) on patient outcomes under e... by Amir Vahedian-Azimi (11177056)

“…These outcomes included longer CPR duration (OR: 1.779, 95%CI: 1.218–2.605, <i> P</i> = 0.034) and decreased survival rates for ECMO at 24 h (OR: 0.561, 95%CI: 0.183–0.903,<i> P</i> = 0.009) and 28 days (OR: 0.498, 95%CI: 0.106–0.802, <i> P</i> = 0.011). …”

A component analysis of positive behaviour support plans by Grey, Ian

“…Measures of challenging behaviour were taken at baseline, after 6 months, and at an average of 26 months follow-up. …”
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Influence of direct electric field on PMCG-alginate-based microcapsule by Peter Kasak (1360617)

“…Microcapsules showed swelling and decreasing mechanical properties under the applied electric current, and the microcapsule membrane showed anisotropic swelling on the electrode side. …”

Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants by Snigdhendubala Pradhan (9872262)

“…This study demonstrates that biochar application at 2–6% is an effective means to increase chickpea yield and reduce water stress. Given small differences in performance within this application range, 2% application is recommended. …”

Chemotherapy prior to Hepatic Resection for Colorectal Liver Metastases: Helpful until Harmful? by Abdalla, Eddie K.

“…Importantly, bevacizumab decreases the incidence and severity of sinusoidal injury with oxaliplatin therapy. …”
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Acute spasticity in malignant MCA stroke: a case report and review of literature by Muhammad Faizan (12710607)

“…Spasticity, a common sequela of stroke, typically occurs days to weeks after the initial event. However, an acute onset of spasticity at presentation is extremely rare. …”

Using a Cavitation Model to Represent the Acoustic Release Kinetics from Folated Micelles by Tanbour, Rafeeq Kamal

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Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis by Meritxell Espino‐Guarch (22565774)

“…Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …”

Kinetics and thermodynamics of acoustic release of doxorubicin from non-stabilized polymeric micelles by Husseini, Ghaleb

“…The release and re-encapsulation of Dox into Pluronic® P105 micelles was measured by recording the fluorescence of a solution of 10 μg/ml Dox and 10 wt% P105 polymer in phosphate-buffered saline, during and after insonation by ultrasound at three temperatures (25 °C, 37 °C and 56 °C). …”
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Fracture Behavior of ASTM A633 steel plate specimens with edge crack at tensile test by Abi Shdid, Caesar

“…This paper evaluates the effect of crack length on the load-displacement curve and also fracture behavior of steel specimens is investigated after tensile tests. Results show that with crack length increasing, yield strength, the ultimate tensile strength, and fracture stress show a decreasing trend. …”
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Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains by Riachi, Naji J.

“…We studied 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in 5 strains of rats by assessing mortality and brain monoamine changes after MPTP injections into the internal carotid artery. …”
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Distribution of Doxorubicin in Rats Undergoing Ultrasonic Drug Delivery by Staples, Bryant J.

“…One of two frequencies with identical mechanical index and intensity was delivered for 15 min to one tumor immediately after systemic injection of micellar Dox. Pharmacokinetics in myocardium, liver, skeletal muscle, and tumors were measured for 1 week. …”
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Bulk passivation of perovskite films utilizing halide anion ionic liquids by Alashkar, Adnan

“…The decay of charge carriers within the perovskite film before and after passivation with ILs was measured by Time Resolved Photoluminescence Spectroscopy (TRPL). …”
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Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making by Almutairi, Adel F.

“…This study aims to investigate the Saudi public’s attitude toward FIH clinical trials, identify their willingness to take part in it, and their preferences for participating in these kinds of trials, given the fact that the Saudi FDA has never approved such studies in Saudi Arabia. …”
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Chronic reduction of store operated Ca²⁺ entry is viable therapeutically but is associated with cardiovascular complications by Fang Yu (156838)

“…<p>Loss of function mutations in store-operated Ca²⁺ entry (SOCE) are associated with severe paediatric disorders in humans, including combined immunodeficiency, anaemia, thrombocytopenia, anhidrosis and muscle hypotonia. Given its central role in immune cell activation, SOCE has been a therapeutic target for autoimmune and inflammatory diseases. …”