Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal by Zehra Irshad (18614869)

“…Silencing of HK-2 prevented increased glucose metabolism and MG formation. trans-Resveratrol and hesperetin combination (tRES-HESP) corrected increased MG and glucose metabolism by increasing expression of Glo1 and decreasing expression of HK-2. Increased MG glycation activates the UPR in endothelial cells and thereby may contribute to endothelial cell dysfunction in diabetic vascular disease where tRES-HESP may provide effective therapy.…”

Driving and hypoglycemia by Stephen Beer (5480411)

“…Unfortunately most diabetes medication can cause hypoglycemia. Hypoglycemia has been associated with cardiac arrhythmia, a decreased ability to drive and driving mishap. …”

The promise of tirzepatide: A narrative review of metabolic benefits by Sara Sokary (17337724)

“…<p>Obesity and type 2 diabetes mellites (T2DM) are intertwined epidemics that continue to pose significant challenges to global public health. …”

Correlations between Resting Electrocardiogram Findings and Disease Profiles: Insights from the Qatar Biobank Cohort by Fatima Qafoud (14778571)

“…Elevated QTc was observed in CAD patients, whereas decreased QTc was correlated with decreased levels of calcium and potassium. …”

Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study by Ayman Al-Dahshan (8962568)

“…The elderly population is the most susceptible to the negative effects of polypharmacy due to their altered pharmacokinetics and decreased drug clearance. Therefore, polypharmacy can lead to poor health status and higher rates of morbidity and mortality. …”

Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study by Ayman Al-Dahshan (8962568)

“…The elderly population is the most susceptible to the negative effects of polypharmacy due to their altered pharmacokinetics and decreased drug clearance. Therefore, polypharmacy can lead to poor health status and higher rates of morbidity and mortality. …”

From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease by Ahmad Raza (18205961)

“…<p dir="ltr">Type 2 Diabetes (T2D) and Alzheimer’s Disease (AD) share common risk factors that can be seen through T2D nearly doubling an individual’s likelihood of developing AD. …”

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes by Shadi Nejat (19457212)

“…Similarly, KO 47 mice also showed a slower rate of glucose clearance in GTT that was consistent with decreased mRNA expression of the GLUT4 gene in WAT but not in the muscle. …”

The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global... by Farin Kamangar (63964)

“…Between 1990 and 2017, age-standardised incidence decreased by 22·0% (18·6–25·2), mortality decreased by 29·0% (25·8–32·0), and DALYs decreased by 33·4% (30·4–36·1) globally. …”

Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE by SHAREEF, SUNDUS LUAY

“…Moreover, the research found that the variation in building heights will increase the wind velocity by up to 23 %, and this improvement in air flow affects the outdoor air temperature positively. …”
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Performance comparison of different flow arrangements of 4-fluid internally-cooled liquid desiccant dehumidifiers by Ali Pakari (14158902)

“…The results showed that the best performance, in terms of the supply air humidity ratio and enthalpy decrease, was obtained when the supply air was in counter-flow with the exhaust air, liquid desiccant, and water. …”

Thermodynamic analysis of a new renewable energy based hybrid system for hydrogen liquefaction by Ratlamwala, Tahir Abdul Hussain

“…It is found that when mass flow rate of air increases the energetic and exergetic COPs decrease in an exponential form from 2.6 to 1.9, and 0.4 to 0.3, respectively. …”
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An improved non-dimensional model of wet-cooling towers by QURESHI, BILAL AHMED

“…The first method shows a maximum decrease of 4.4 per cent in error, whereas in the second method, the maximum error was found to be 3.3 and 6.8 per cent when the inlet air was unsaturated and saturated, respectively. …”
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Exploring urban growth–climate change–flood risk nexus in fast growing cities by Salah Basem Ajjur (14150967)

“…Surveying showed that, between 1984 and 2020, urban areas grew by 777%, and bare lands decreased by 54.7%. In addition, Doha witnessed various climatic changes with a notable increase in air temperature (+ 8.7%), a decrease in surface wind speed (− 19.5%), and a decrease in potential evapotranspiration losses (− 33.5%). …”

Daucus Carota oil extract, a chemotherapeutic agent, acts as an antidepressant that promotes resilience to chronic social defeat stress by Houbeika, Rouba

“…It is used as folk medicine to treat many diseases such as diabetes mellitusand cancer. β-2-himachalen-6-ol (HC-6-ol), its major compound, causes a dose-dependent decrease in cell viability, induces cell cycle arrest, and promotes apoptosis in cancer cells. …”
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Comparative Analysis of Thermal Conditions and Comfort Between Modern and Traditional Districts in Hot-Arid Climate: Case Study in Ajman-UAE by Salameh, Muna

“…Additionally, the research output revealed that the traditional urban design has valuable, sustainable strategies, as there was a decrease in the maximum reading for the air temperature for the traditional Ajman heritage district compared to the modern district on the 21st of August - as a reference day- and that improved the thermal comfort in the outdoor open spaces too. …”
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Stemming cardiovascular diseases in Qatar by Nature Research (16552612)

“…“Both Qatari nationals and expatriates should adopt healthier lifestyles to reduce the prevalence of these risk factors,” says Christos. Diabetes was the largest preventable risk factor to decrease heart attacks and strokes.…”

Structural Hole Theory, Audit Committee Member Gender, and Financial Restatements by Radaideh, Farah Ghazi

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Tabu search based circuit optimization by Sait, Sadiq M.

“…Such a strategy leads to sizable circuit speed improvement with minimum increase in the overall circuit capacitance. Compared to earlier approaches, the presented technique produces circuits with remarkable increase in speed (greater than 20%) for very small increase in overall circuit capacitance (less than 3%)…”
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Reliability of high strain ionomeric polymer transducers fabricated using the direct assembly process by Akle, Barbar

“…Water-hydrated transducers dehydrate and stop moving within 5 min while operating in air under the application of ± 2 V. Ionic liquid based transducers are demonstrated to operate in air for over 400 000 cycles with little loss in performance, and are reliable up to 1 million cycles with a performance loss of less than 43%. …”
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