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441
From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease
Published 2025“…This review focuses on the potential mechanisms associated with these two diseases, like insulin resistance, inflammation, oxidative damage, mitochondrial injury, and cell death. …”
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442
Impact of the fear of Covid-19 infection on intent to breastfeed; a cross sectional survey of a perinatal population in Qatar
Published 2022“…Breastfeeding requires close physical contact and observance of hygienic measures like handwashing. Worries around contamination increase during the perinatal period and can be expressed as increase in obsessive compulsive symptoms. …”
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443
Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants
Published 2022“…This study demonstrates that biochar application at 2–6% is an effective means to increase chickpea yield and reduce water stress. Given small differences in performance within this application range, 2% application is recommended. …”
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444
Automatic image quality evaluation in digital radiography using for‐processing and for‐presentation images
Published 2024“…</p><h3>Methods</h3><p dir="ltr">A custom‐made phantom constructed according to the instructions given in the IAEA Human Health Series No.39 publication was used, along with the respective software that automatically calculates various IQ metrics. …”
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445
Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021
Published 2024“…Additionally, we introduced two new metrics to our reporting: prevalence of unsuppressed viraemia (PUV), which represents the proportion of the population without a suppressed level of HIV (viral load <1000 copies per mL), and period lifetime probability of HIV acquisition, which quantifies the hypothetical probability of acquiring HIV for a synthetic cohort, a simulated population that is aged from birth to death through the set of age-specific incidence rates of a given time period. FindingsGlobal new HIV infections decreased by 21·9% (95% UI 13·1–28·8) between 2010 and 2021, from 2·11 million (2·02–2·25) in 2010 to 1·65 million (1·48–1·82) in 2021. …”
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446
Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults
Published 2022“…After three-months supplementation of 50,000IU, vitamin D levels increased to 51.41 ±11.27ng/ml in the supplemented group and to24.95 ±6.45ng/ml in placebo group (p=0.00). PHQ-9 scores decreased from 12.53 ±5.33 to 4.92 ±2.44 in vitamin D group (p <0.001), and from 12.46 ±4.66 to 8.96±3.75in the control group (p<0.001), indicating enhancement in depressive symptomatology. …”
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447
The effect of microbiome therapy on COVID-19-induced gut dysbiosis: A narrative and systematic review
Published 2024“…Further, bidirectional communication between the gastrointestinal tract and vital organs like the lung, heart, brain, and liver can exacerbate the disease severity and cause further inflammation and dysbiosis. …”
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448
Novel proteins implicated in lipid metabolism disorders
Published 2016“…After feeding, its expression is decreased, promoting the uptake of dietary lipids in fat tissue. …”
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449
Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
Published 2025“…Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …”
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450
Biomarkers show promise for treatment of heart valve disease
Published 2015“…They are also comparing the levels of valve tissue markers with microRNAs and toll-like receptors, proteins involved in the immune system, in experimentally produced aortic stenosis in rabbits.…”
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451
Business Continuity Management Maturity Model for Banks in UAE
Published 2008“…They are faced with increasing levels of global competition, demanding customers and employees, shrinking product lifecycles and decreasing acceptable response times (Lockamy & McCormack, 2004) They have employees and deal with clients, suppliers & vendors from all over the world. …”
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452
Chronic reduction of store operated Ca<sup>2+</sup> entry is viable therapeutically but is associated with cardiovascular complications
Published 2022“…<p>Loss of function mutations in store-operated Ca<sup>2+</sup> entry (SOCE) are associated with severe paediatric disorders in humans, including combined immunodeficiency, anaemia, thrombocytopenia, anhidrosis and muscle hypotonia. Given its central role in immune cell activation, SOCE has been a therapeutic target for autoimmune and inflammatory diseases. …”
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453
Pore-scale simulation of fine particles migration in porous media using coupled CFD-DEM
Published 2022“…<p dir="ltr">Transport of fine particles in porous media has attracted a considerable interest over the past several decades given its importance to many industrial and natural processes. …”
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454
Mitigating the impact of cultural diversity on the innovation process in the private sector in Dubai
Published 2017“…It is true that the aim of any business is to make profit, with decreased profit in the sector many entrepreneurs have discovered other investment schemes which has resulted to more demand of the workforce. …”
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455
Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership
Published 2019“…The author’s line of argument is that conceptual skills are likely to play a significant role in ambidexterity leadership for innovation. …”
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456
Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery
Published 2019“…<h3>Background: </h3><p dir="ltr">Early metabolic responses following bariatric surgery appear greater than expected given the initial weight loss and coincide with improvement in diabetes. …”
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457
Can bitcoin’s volatility be tamed?
Published 2018“…Bitcoin is a software for operating a peer-to-peer payment network with its own hard money, without having to rely on a trusted third party. …”
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458
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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)
Published 2023“…<p dir="ltr">Dysregulated epigenetic modifications are common in lung cancer but have been reversed using demethylating agent like 5-Aza-CdR. 5-Aza-CdR induces/upregulates the NY-ESO-1 antigen in lung cancer. …”
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460
Psychological and Coping Strategies Related to Home Isolation and Social Distancing in Children and Adolescents During the COVID-19 Pandemic: Cross-sectional Study
Published 2021“…Participants experiencing higher levels of anxiety should be given more attention during reintegration and transitional phases in schools. …”