ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] by Abdel Khalek, Maya

“…In this study, we examine the mechanism of HuArgI (Co)-PEG5000-induced cell death in both partially and completely auxotrophic GBM cell lines. Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …”
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Deep Learning-Based Fault Diagnosis of Photovoltaic Systems: A Comprehensive Review and Enhancement Prospects by Majdi Mansouri (16869885)

“…These faults may affect the different system components such as PV modules, connection lines, converters/inverters, which can lead to a decrease in the efficiency, performance, and further system collapse. …”

Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy by Taki, Fatima

“…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …”
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Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”

Country of birth affects blood pressure in the French hypertensive diabetic population by Bahous, Sola Aoun

“…The combination of diabetes and hypertension in African populations was associated with increased aortic stiffness and PP, together with greater body weight and WHR. …”
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STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration by Ayat S. Hammad (9592374)

“…In contrast, Orai1-KO cells, which have similar levels of SOCE inhibition as STIM1-KO, migrate slower than the parental cell line. This shows that the enhanced migration phenotype of STIM1-KO cells is not due to the loss of Ca²⁺ entry through SOCE, rather it involves transcriptional remodeling as elucidated by RNA-seq analyses. …”

Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases by Glazer, Evan

“…For example, a few years ago an extrahepatic metastasis effectively eliminated surgical resection, but a combination of chemotherapeutic options and surgical techniques has expanded the indications for resection and increased the population of patients who may benefit.1,2 Neoadjuvant chemotherapy has increased the resectability rate by 11% to 37%.1 Unfortunately, greater than 80% of patients undergoing hepatic resection will have recurrences, mostly within the first 2 years.2 Nonetheless, the only hope for cure is resection, and prior surgical dogma based on the number of lesions, size of the tumor-free resection margin, and presence of resectable extrahepatic disease must be questioned.3- 5 The current standard approach to surgical planning is contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) for specific tumor characteristics or contraindications to CT.6 Several series showed that focal extrahepatic disease, an isolated pulmonary lesion, can be safely resected, with 5-year survival rates of 29% to 58%.7,8 In 1 series,7 17 of 30 patients required 3 or more resections. …”
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Numerical Investigation of Flexural Behavior of Reinforced Concrete (RC) T-Beams Strengthened with Pre-Stressed Iron-Based (FeMnSiCrNi) Shape Memory Alloy Bars by Khalil, Ahmed

“…Based on the numerical results, it was found that increasing the compression strength from 30 to 60 MPa slightly improves the beam’s strength (by 2%), but it significantly increases its ductility by approximately 45%. …”
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Longitudinal Study of Hypertensive Subjects With Type 2 Diabetes Mellitus by Bahous, Sola Aoun

“…Mortality was significantly greater among diabetic than nondiabetic hypertensive subjects (all-cause mortality, 14.05% versus 7.43%; and cardiovascular mortality, 1.28% versus 0.7%). …”
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Five-Level MLI-Based Grid-Connected Photovoltaic Systems: A Review on Control Methodologies, Modulation Strategies and Recent Developments by Anurag Tiwari (3563561)

“…Five-level MLI-based PV systems have become a crucial option as the relevance of renewable energy keeps increasing because of their increased efficiency, less harmonic distortion, and greater power quality. …”

Impacts of Diverse Workforce on Cyber Security and Information Technology Management by ALHEBSI, WADDAH SULTAN

“…Despite these findings, organizations should continue to consider the potential benefits of diversity in the cybersecurity workforce, including improved decision-making, increased adaptability, enhanced creativity, greater representation, and improved team performance. …”
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Associating learning technology to sustain the environment through green mobile applications by Haraty, Ramzi A.

“…With “quality education” a major issue for the UN 2030 Sustainable Development Agenda, it is a must that we loop together the “quality education” with education per se. It is imperative that we engage the youth in attaining this objective, for it is not enough that we empower them with the tools, we must encourage them to look at the current issues outside the box, through a worldwide view, where the focus nowadays is on the environment, be it in reducing fuel usage, decreasing air and water pollution, and recycling, in brief, being environment friendly. …”
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Acute pain management and assessment by Zeitoun, Abeer A.

“…Appropriateness of pain management was determined as per World Health Organization guidelines. Institutional Review Board approvals were obtained from each hospital. …”
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Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways by Shehaby, Wassim N.

“…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …”
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Effect of temperature on the rheological properties of neat aqueous Wyoming sodium bentonite dispersions by Vryzas, Zisis

“…The Bingham yield stress, from the low shear rate data, increased linearly with temperature, while the plastic viscosity decreased with temperature, in a manner very similar to the decrease of water viscosity with temperature. …”
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A Quadratic Non-Isolated High Step-Up Single-Input Dual-Output DC–DC Topology Based on Coupled Inductors with Low Input Current Ripple by Vafa Marzang (17347048)

“…The proposed converter produces high DC output voltages at a low value of duty cycles and low voltage stress across the power MOSFETs. The CIs’ turn ratios give another freedom factor to increase the output voltages and decrease the switches’ stress. …”

Effect of anions on the structural, morphological and dielectric properties of hydrothermally synthesized hydroxyapatite nanoparticles by Lakshmanaperumal Sundarabharathi (14152482)

“…The εʹ and dielectric loss (εʹʹ) values for the HA nanoparticles decrease with increase in the applied frequency as well. …”

Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma by Shebaby, W.

“…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …”
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Effect of StarD13 on colorectal cancer proliferation, motility and invasion by Nasrallah, Anita

“…Colon cancer is a cancer of the epithelial cells lining the colon. It is mainly divided into different stages according to the invasiveness and metastatic ability of the tumor. …”
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Disciplinary action against physicians: Who is likely to get disciplined? by Dimassi, Hani

“…Kaplan-Meier analysis revealed that the proportion of physicians disciplined increased with each successive 10-year interval since first licensure. …”
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