Characterizing the Effect of Arginine Deprivation on Autophagic Response in Breast Cancer cells by Haidar, Fatemah

“…In this project, we first inspected ASS-1 expression in human breast cancer patients and found that it decreases progressively with tumorigenesis and metastasis. …”
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COPE for adolescent Syrian refugees in Lebanon: a brief cognitive–behavioral skill-building intervention to improve quality of life and promote positive mental health by Doumit, Rita

“…Feasibility and acceptability findings indicated that the COPE program was a positive experience for teens. Significant decreases in depression and anxiety, and increases in QOL were also reported. …”
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Intravitreal adalimumab in active noninfectious uveitis by Hamam, Rola N.

“…Seven out of 12 eyes had improvement of ≥2 ETDRS lines. Three out of three eyes had resolution of anterior chamber cells. …”
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Global pattern, trend, and cross-country inequality of early musculoskeletal disorders from 1990 to 2019, with projection from 2020 to 2050 by Yingzhao, Jin

“…The disease burden of gout, LBP, and OA attributable to high BMI and gout attributable to kidney dysfunction increased, while the contribution of smoking to LBP and RA and occupational ergonomic factors to LBP decreased. Between 1990 and 2019, the slope index of inequality increased for six MSK disorders, and the relative concentration index increased for gout, NP, OA, and OMSKDs but decreased for LBP and RA. …”
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Investigating the Role of Acetyl-CoA Synthetase Short Chain Family Member 2 (ACSS2) in Inflammatory Bowel Disease: Expression in Clinical Samples and Insights from In Vitro Models by Mezher, Nawal

“…Using Caco-2 and HT-29 intestinal epithelial cell lines stimulated with Tumor Necrosis Factor-α (TNF-α) or Dextran Sodium Sulfate (DSS) as in vitro models of inflammation, we observed upregulation of ACSS2 protein expression. …”
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Connexin 43 Loss Triggers Cell Cycle Entry and Invasion in Non-Neoplastic Breast Epithelium: A Role for Noncanonical Wnt Signaling by Fostok, Sabreen

“…Background: The expression of connexin 43 (Cx43) is disrupted in breast cancer, and re-expression of this protein in human breast cancer cell lines leads to decreased proliferation and invasiveness, suggesting a tumor suppressive role. …”
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Run Rules-Based EWMA Charts for Efficient Monitoring of Profile Parameters by Ali Yeganeh (16624998)

“…., intercept, slope and average residual between sample and reference lines) by integrating them with run rules in order to quickly detect various magnitudes of shifts in profile parameters. …”

Breast cancer cells and bone marrow mesenchymal stromal cells by Faour, Wissam H.

“…Co-cultures with either MG-63 cells or MSCs induced OPG and MMP-2 in both tumor cell lines. Interestingly, conditioned medium from co-cultures of MSCs and MDA-MB-231 cells significantly decreased the proliferation of activated T lymphocytes which was reversed by addition of anti-OPG antibodies to the co-cultures. …”
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Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes by Shadi Nejat (19457212)

“…Three DNAJB3 knockout (KO) lines were generated (KO 30, 44 and 47), using CRISPR-Cas9. …”

The burden of prostate cancer in North Africa and Middle East, 1990–2019: Findings from the global burden of disease study by Mohsen Abbasi-Kangevari (9714440)

“…This study presents estimates of PCa prevalence, incidence, death, years-of-life-lost (YLLs), years-lived-with-disability (YLDs), disability-adjusted-life-years (DALYs), and the burden attributable to smoking during 1990-2019 in North Africa and Middle East using data of Global Burden of Diseases (GBD) Study 2019.…”

Intravitreal bevacizumab (Avastin) treatment of retinal angiomatous proliferation by Ghazi, Nicola G.

“…Results: Twelve eyes (92.3%) had stable or improved BCVA, and 8 eyes (61.5%) had at least 2 lines of vision improvement. The average BCVA improved from 20/203 at baseline to 20/113 at 12 weeks (P = 0.001). …”
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PSA-activated proaerolysin as a prostate specific cancer therapy by Abi-Habib, Ralph

“…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …”
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The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013) by Khoury, Nathalie El

“…In this study, we aim to determine a possible mechanism of action of kefir and to study its effect on the motility of colorectal and breast cancer cell lines. Results from the reverse-transcription PCR experiment have shown that kefir decreases the expression of TGF-α and TGF-β1 in HT-29 cells in a dose dependent manner. …”
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ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder by Sara Cuvertino (18892069)

“…<i>ACTB</i> mRNA expression levels in lymphoblastic lines and fibroblasts derived from affected individuals were decreased in comparison to those in control cells. …”

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…Gaussian accelerated molecular dynamics (GaMD) simulations of the predicted alpha-helical synthetic Mpro cleavage sequences revealed a dynamic nature of the cleavage sequences, which is critical for their efficient cleavage, and a relatively short end-to-end distances, which is required for high BRET. Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …”
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Addressing Challenges of Distance Learning in the Pandemic with Edge Intelligence Enabled Multicast and Caching Solution by Kashif Bilal (16896357)

“…Moreover, user preferences and network’s contextual information can differentiate between live and cached access patterns optimizing edge caching decisions. …”

Cross-Cultural Awareness and Attitudes Toward Threatened Animal Species by Jennifer Bruder (323066)

“…<p dir="ltr">The preservation of our planet’s decreasing biodiversity is a global challenge. Human attitudes and preferences toward animals have profound impacts on conservation policies and decisions. …”

Do Older Adults with Multimorbidity Meet the Recommended Levels of Physical Activity? An Analysis of Scottish Health Survey by Ahmad Salman (3173418)

“…Independent predictors of meeting the recommended levels of PA include male gender [odds ratio (OR) 2.00 (95% confidence interval (CI) 1.58–2.54)], living in the least deprived areas [OR 1.79 (95% CI 1.20–2.69)]; being a non-smoker [OR 2.22 (95% CI 1.48–3. 34)]. …”

An Investigation into the factors influencing Arabic speaking students’ proficiency in the Arabic language in Dubai British School by AL AHMAD, ALAAEDDIN MEHY

“…However, those Arabic-speaking students attending non-Arabic schools become less proficient in the Arabic language and continually fall behind their peers in Arabic schools. This is despite the fact that both groups of students are native Arabic speakers, and that both groups of students attend Arabic classes that use the same curriculum and textbooks. …”
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Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death by Tohme, Sara

“…Scavenging ROS using NAC significantly decreases cell death but has minimal effect on autophagy activation, suggesting that the accumulation of ROS is downstream of autophagy activation but upstream of cell death. …”
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