Connexin 43 Loss Triggers Cell Cycle Entry and Invasion in Non-Neoplastic Breast Epithelium: A Role for Noncanonical Wnt Signaling by Fostok, Sabreen

“…Background: The expression of connexin 43 (Cx43) is disrupted in breast cancer, and re-expression of this protein in human breast cancer cell lines leads to decreased proliferation and invasiveness, suggesting a tumor suppressive role. …”
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Run Rules-Based EWMA Charts for Efficient Monitoring of Profile Parameters by Ali Yeganeh (16624998)

“…., intercept, slope and average residual between sample and reference lines) by integrating them with run rules in order to quickly detect various magnitudes of shifts in profile parameters. …”

Breast cancer cells and bone marrow mesenchymal stromal cells by Faour, Wissam H.

“…Co-cultures with either MG-63 cells or MSCs induced OPG and MMP-2 in both tumor cell lines. Interestingly, conditioned medium from co-cultures of MSCs and MDA-MB-231 cells significantly decreased the proliferation of activated T lymphocytes which was reversed by addition of anti-OPG antibodies to the co-cultures. …”
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Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes by Shadi Nejat (19457212)

“…Three DNAJB3 knockout (KO) lines were generated (KO 30, 44 and 47), using CRISPR-Cas9. …”

Intravitreal bevacizumab (Avastin) treatment of retinal angiomatous proliferation by Ghazi, Nicola G.

“…Results: Twelve eyes (92.3%) had stable or improved BCVA, and 8 eyes (61.5%) had at least 2 lines of vision improvement. The average BCVA improved from 20/203 at baseline to 20/113 at 12 weeks (P = 0.001). …”
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PSA-activated proaerolysin as a prostate specific cancer therapy by Abi-Habib, Ralph

“…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …”
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The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013) by Khoury, Nathalie El

“…In this study, we aim to determine a possible mechanism of action of kefir and to study its effect on the motility of colorectal and breast cancer cell lines. Results from the reverse-transcription PCR experiment have shown that kefir decreases the expression of TGF-α and TGF-β1 in HT-29 cells in a dose dependent manner. …”
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ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder by Sara Cuvertino (18892069)

“…<i>ACTB</i> mRNA expression levels in lymphoblastic lines and fibroblasts derived from affected individuals were decreased in comparison to those in control cells. …”

PROACT: Parallel multi-miner proof of accumulated trust protocol for Internet of Drones by Mershad, Khaleel

“…In addition, we propose a new blockchain consensus mechanism in which several miners produce their blocks in parallel, which decreases the time needed to add transactions securely to the blockchain and meets the requirements of delay-sensitive applications. …”
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Effects of electrolytes and suwannee river humic acid on the aggregation behavior of silicon nanoparticles by Wazne, Mahmoud

“…Studies about the impact of the release of silicon nanomaterials to the environment and on human health by the microelectronics and biomedical devices industries are urgently needed. The aggregation kinetics of silicon NPs was investigated using dynamic light scattering (DLS) and electron microscope (EM) in the presence of Ca2+ and Suwannee River Humic Acid (SRHA). …”
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Sitagliptin/Simvastatin by Ramadan, Wijdan H.

“…Both medications have also demonstrated an acceptable side effect profile. However, caution is needed when coadministering with any drug that may increase simvastatin levels to reduce the risk of myopathy and rhabdomyolysis. …”
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An Investigation into the factors influencing Arabic speaking students’ proficiency in the Arabic language in Dubai British School by AL AHMAD, ALAAEDDIN MEHY

“…However, those Arabic-speaking students attending non-Arabic schools become less proficient in the Arabic language and continually fall behind their peers in Arabic schools. This is despite the fact that both groups of students are native Arabic speakers, and that both groups of students attend Arabic classes that use the same curriculum and textbooks. …”
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Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death by Tohme, Sara

“…Scavenging ROS using NAC significantly decreases cell death but has minimal effect on autophagy activation, suggesting that the accumulation of ROS is downstream of autophagy activation but upstream of cell death. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion by Khoury, Nathalie

“…Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. …”
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Percutaneous Transhepatic Bile Duct Ablation with n-Butyl Cyanoacrylate in the Treatment of a Biliary Complication after Split Liver Transplantation by Lauterio, Andrea

“…Further studies are needed to determine whether this approach is effective and safe and whether it could reduce hospital stay and cost.…”
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Heat Transfer Coefficient Estimation of Falling Film for Horizontal Tube Multi-Effect Desalination Evaporator Using CFD by Furqan Tahir (14429547)

“…Furthermore, the higher operating temperature limit should be increased instead of decreasing operating temperature for improved heat transfer performance.…”

Techno-economic and environmental analyses of the pyrolysis of food waste to produce bio-products by Mohammad Alherbawi (14155767)

“…The water footprint increased with increasing pyrolysis temperature but decreased with increasing moisture content in all scenarios. …”

Antibody‐based methods for the measurement of α‐synuclein concentration in human cerebrospinal fluid – method comparison and round robin study by Brit Mollenhauer (482499)

“…The use of common reference CSF samples decreased the differences in α‐synuclein concentration between detection methods and technologies. …”

Production of self-compacting concrete using Jordanian oil shale ash by Ashteyat, Ahmed

“…The strength of the SCC concrete decreased with higher OSA replacement contents although maintaining a higher value than that of conventional concrete made at almost the same cement factor. …”
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Fixed-interval versus OCT-guided variable dosing of intravitreal bevacizumab in the management of neovascular age-related macular degeneration by El-Mollayess, Georges M.

“…Purpose To compare the efficacy of as-needed or variable dosing of intravitreal bevacizumab to continuous fixed-interval dosing in the management of neovascular age-related macular degeneration (AMD). …”
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