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401
eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
Published 2018“…Furthermore, we show that hippuristanol perturbs the activation of the STAT3 pathway and expression of STAT3-gene targets such as IL-6. The decreased activation of STAT3, which resulted from a decrease in STAT3 protein expression, was due to the inhibition of STAT3 translation as there were no changes in STAT3 mRNA levels. …”
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402
Nox2 Activity Is Required in Obesity-Mediated Alteration of Bone Remodeling
Published 2018“…Our results show that HFD increased bone mineral density to a greater extent in KO mice than in WT mice without affecting the total body weight and fat mass. …”
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403
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…Recent studies revealed that enhanced PD-L1 expression in cancer stem cells is linked to immune evasion. Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …”
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404
The association between tobacco use and COVID-19 in Qatar
Published 2022“…Our data suggests that only smokeless tobacco users may be at an increased risk for severe disease, yet this requires further investigation as other studies have reported smoking to be associated with an increased risk of greater disease severity.…”
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405
Exploring the Impacts of Artificial Intelligence (AI) Technology Implementation at the Individual and Team Levels_
Published 2023“…The public sector is under increasing pressure to deliver efficient services, attain high levels of customer satisfaction, and meeting the pressing societal needs. …”
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406
Iron slag/activated carbon-electrokinetic system with anolyte recycling for single and mixture heavy metals remediation
Published 2024“…The copper removal increased to 89.21 % when the anolyte solution was recycled to the cathode compartment. …”
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407
Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019
Published 2021“…Since 1950, deaths in this age group decreased by 30·0% in females and 15·3% in males, and sex-based differences in mortality rate have widened in most regions of the world. …”
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408
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410
A modified lipid composition in Fabry disease leads to an intracellular block of the detergent-resistant membrane-associated dipeptidyl peptidase IV
Published 2010“…Fabry disease is an X-linked lysosomal storage disorder that leads to abnormal accumulation of glycosphingolipids due to a deficiency of alpha-galactosidase A (AGAL). …”
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411
Breast cancer cells and bone marrow mesenchymal stromal cells
Published 2017Get full text
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412
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413
Exploring Ultra-Processed Foods: Impact on Satiety, Eating Patterns, Blood Glucose Levels and Food Addiction
Published 2025“…Results: Higher UPF intake was significantly associated with lower enjoyment of food (p = 0.002), greater food cravings (p = 0.003), and higher food addiction (FA) symptoms (p < 0.001). …”
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masterThesis -
414
The Role of Epidermal Growth Factor Receptor Family of Receptor Tyrosine Kinases in Mediating Diabetes-Induced Cardiovascular Complications
Published 2021“…<p dir="ltr">Diabetes mellitus is a major debilitating disease whose global incidence is progressively increasing with currently over 463 million adult sufferers and this figure will likely reach over 700 million by the year 2045. …”
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415
Rethinking (un)blinding in biomedical proposal peer review: A multi-stakeholder qualitative study
Published 2025“…These shortcomings highlight the need for greater openness in peer review and increased transparency in fund allocation processes.…”
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416
Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines
Published 2016“…Similarly, the droplet size of Intralipid increased from 283.3 to 294.6nm on inclusion of 6mg/ml paclitaxel. …”
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417
Detecting attacks in a cluster based QOS-OLSR protocol. (c2014)
Published 2014Get full text
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418
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419
A Power Ripple Compensator for DC Nanogrids via a Solid-State Converter
Published 2020“…This SSC is often considered as the main DC nanogrid energy control unit that is linking the nanogrid with the main utility AC grid and managing the nanogrid elements. …”
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420